Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1978142..1978287 Replicon chromosome
Accession NZ_CP034778
Organism Klebsiella pneumoniae strain 18CPO060

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1978178..1978280 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1978142..1978287 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ENZ43_RS11705 1973272..1975332 + 2061 WP_004151449.1 oligopeptidase B -
ENZ43_RS11710 1975336..1975995 - 660 WP_002911407.1 exodeoxyribonuclease X -
ENZ43_RS11715 1976074..1976304 - 231 WP_002911406.1 DNA polymerase III subunit theta -
ENZ43_RS11720 1976417..1976791 + 375 WP_004151448.1 CopC domain-containing protein YobA -
ENZ43_RS11725 1976795..1977664 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
ENZ43_RS11730 1977681..1978019 + 339 WP_002911404.1 YebY family protein -
- 1978142..1978287 - 146 - - Antitoxin
- 1978178..1978280 + 103 - - Toxin
ENZ43_RS28000 1978654..1978797 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
ENZ43_RS11740 1978902..1979870 - 969 WP_004151446.1 VirK/YbjX family protein -
ENZ43_RS11745 1980027..1980680 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
ENZ43_RS11750 1980677..1980868 - 192 WP_002911395.1 YebW family protein -
ENZ43_RS11755 1980966..1981205 - 240 WP_002911393.1 YebV family protein -
ENZ43_RS11760 1981321..1982754 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T116494 NZ_CP034778:1978178-1978280 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT116494 NZ_CP034778:c1978287-1978142 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References