Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1932971..1933116 Replicon chromosome
Accession NZ_CP034760
Organism Klebsiella pneumoniae strain NB5306

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1933007..1933109 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1932971..1933116 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EMI85_RS09690 1928101..1930161 + 2061 WP_004151449.1 oligopeptidase B -
EMI85_RS09695 1930165..1930824 - 660 WP_021440386.1 exodeoxyribonuclease X -
EMI85_RS09700 1930903..1931133 - 231 WP_002911406.1 DNA polymerase III subunit theta -
EMI85_RS09705 1931246..1931620 + 375 WP_004151448.1 CopC domain-containing protein YobA -
EMI85_RS09710 1931624..1932493 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
EMI85_RS09715 1932510..1932848 + 339 WP_002911404.1 YebY family protein -
- 1932971..1933116 - 146 - - Antitoxin
- 1933007..1933109 + 103 - - Toxin
EMI85_RS27375 1933485..1933628 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
EMI85_RS09725 1933733..1934701 - 969 WP_073971755.1 VirK/YbjX family protein -
EMI85_RS09730 1934858..1935511 + 654 WP_032441330.1 protein-serine/threonine phosphatase -
EMI85_RS09735 1935508..1935699 - 192 WP_002911395.1 YebW family protein -
EMI85_RS09740 1935797..1936036 - 240 WP_002911393.1 YebV family protein -
EMI85_RS09745 1936152..1937585 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T116458 NZ_CP034760:1933007-1933109 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT116458 NZ_CP034760:c1933116-1932971 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References