Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3858527..3859086 Replicon chromosome
Accession NZ_CP034759
Organism Litorilituus sediminis strain JCM 17549

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EMK97_RS17075 Protein ID WP_130603993.1
Coordinates 3858527..3858805 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EMK97_RS17080 Protein ID WP_130603994.1
Coordinates 3858802..3859086 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EMK97_RS17055 3854381..3855184 + 804 WP_130603989.1 metalloregulator ArsR/SmtB family transcription factor -
EMK97_RS17060 3855212..3856228 + 1017 WP_130603990.1 ACR3 family arsenite efflux transporter -
EMK97_RS17065 3856277..3857287 + 1011 WP_130603991.1 ArsJ-associated glyceraldehyde-3-phosphate dehydrogenase -
EMK97_RS17070 3857292..3858512 + 1221 WP_130603992.1 organoarsenical effux MFS transporter ArsJ -
EMK97_RS17075 3858527..3858805 - 279 WP_130603993.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EMK97_RS17080 3858802..3859086 - 285 WP_130603994.1 damage-inducible protein J Antitoxin
EMK97_RS17085 3859289..3859669 - 381 WP_130603995.1 hypothetical protein -
EMK97_RS17090 3859669..3860343 - 675 WP_130603996.1 hypothetical protein -
EMK97_RS17095 3860632..3861771 + 1140 WP_130603997.1 PQQ-dependent sugar dehydrogenase -
EMK97_RS17100 3861829..3862527 - 699 WP_170176801.1 ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10893.66 Da        Isoelectric Point: 4.8839

>T116453 WP_130603993.1 NZ_CP034759:c3858805-3858527 [Litorilituus sediminis]
VIFWEEESLNDREKIFEFLYDVNPKAAEKTDQIIEAKVEHLLEHPLMGVQRDIFPGRLLIIPEISMIISYWLDGSTIRVM
RVLHQKQKFPAE

Download         Length: 279 bp

>T116453 NZ_CP034759:c3858805-3858527 [Litorilituus sediminis]
GTGATTTTTTGGGAAGAAGAGTCGCTTAATGATAGGGAAAAAATATTCGAGTTTCTTTACGATGTTAACCCTAAAGCTGC
CGAAAAAACGGATCAAATAATTGAGGCGAAAGTTGAACATTTGCTGGAGCATCCACTAATGGGTGTTCAACGGGATATTT
TTCCAGGCCGATTATTAATTATTCCAGAAATTTCAATGATCATTTCTTACTGGCTTGATGGAAGCACTATTCGAGTCATG
CGAGTTTTACACCAAAAGCAAAAGTTTCCAGCTGAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11043.37 Da        Isoelectric Point: 8.0516

>AT116453 WP_130603994.1 NZ_CP034759:c3859086-3858802 [Litorilituus sediminis]
MDTRIQFRVDEETKRLAQLMAQSQGRTLSDACRELTERLAEEQRKSMSHDTWLSEQINAAFSKLDSDKANFIAHDEARSL
MEERKQKIRNRSKT

Download         Length: 285 bp

>AT116453 NZ_CP034759:c3859086-3858802 [Litorilituus sediminis]
ATGGACACTCGTATACAATTTAGAGTTGATGAAGAAACCAAACGATTAGCACAGTTGATGGCTCAAAGCCAAGGGCGAAC
TTTAAGTGACGCATGCCGAGAACTTACCGAGCGTTTAGCTGAAGAACAACGAAAATCAATGAGTCATGATACATGGCTAT
CAGAACAAATAAATGCTGCATTTAGTAAGCTTGATAGTGACAAAGCTAATTTTATTGCACATGATGAAGCTAGAAGCTTA
ATGGAAGAAAGAAAACAAAAAATCCGCAACCGGAGTAAAACGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References