Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/RHH(antitoxin)
Location 4623531..4624099 Replicon chromosome
Accession NZ_CP034752
Organism Jinshanibacter zhutongyuii strain CF-458

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag EKN56_RS20755 Protein ID WP_130593533.1
Coordinates 4623531..4623830 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EKN56_RS20760 Protein ID WP_130593534.1
Coordinates 4623818..4624099 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EKN56_RS20730 4619129..4621261 + 2133 WP_210405321.1 oligopeptide transporter, OPT family -
EKN56_RS20735 4621342..4621743 - 402 WP_130593529.1 DUF2628 domain-containing protein -
EKN56_RS20740 4621980..4622582 - 603 WP_130593530.1 YdcF family protein -
EKN56_RS20745 4622830..4623102 + 273 WP_130593531.1 hypothetical protein -
EKN56_RS20750 4623114..4623449 + 336 WP_130593532.1 type II toxin-antitoxin system RelE/ParE family toxin -
EKN56_RS20755 4623531..4623830 - 300 WP_130593533.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EKN56_RS20760 4623818..4624099 - 282 WP_130593534.1 CopG family ribbon-helix-helix protein Antitoxin
EKN56_RS20765 4624534..4624768 - 235 Protein_4065 transposase -
EKN56_RS20770 4624826..4625620 - 795 WP_130593535.1 DUF1911 domain-containing protein -
EKN56_RS20775 4625957..4627177 - 1221 Protein_4067 tyrosine-type recombinase/integrase -
EKN56_RS20780 4627385..4628749 - 1365 WP_130593536.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11472.39 Da        Isoelectric Point: 8.8724

>T116435 WP_130593533.1 NZ_CP034752:c4623830-4623531 [Jinshanibacter zhutongyuii]
MPQVIITQQAAIGLVRCREFLRGKNTLAAIKAGQILEQHFELLKNDPEIGRPFPELPILRELMIKFGDSGYVALYRYHKE
EERVYVLAFRHQKEAGYSL

Download         Length: 300 bp

>T116435 NZ_CP034752:c4623830-4623531 [Jinshanibacter zhutongyuii]
ATGCCACAAGTAATTATTACTCAACAAGCAGCAATAGGACTCGTTCGCTGCCGGGAATTTCTAAGAGGCAAGAATACTCT
GGCTGCTATCAAAGCAGGTCAAATTCTTGAGCAGCATTTTGAGTTACTGAAAAACGATCCTGAAATTGGCAGACCATTTC
CTGAACTACCGATACTGCGAGAGTTAATGATTAAATTCGGTGATTCTGGCTATGTTGCATTATACCGTTATCATAAAGAG
GAAGAGCGAGTTTATGTGTTAGCCTTTCGCCACCAGAAAGAAGCTGGATATTCGCTTTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10924.20 Da        Isoelectric Point: 4.9626

>AT116435 WP_130593534.1 NZ_CP034752:c4624099-4623818 [Jinshanibacter zhutongyuii]
MPTSTTTLKIDNKLRERIKKLADSRDRSPHYLMLAAITEYIEREEAQESFKQEALDSWREYQETGLHLTGDEVKTWLRGW
GTEAETDIPECHK

Download         Length: 282 bp

>AT116435 NZ_CP034752:c4624099-4623818 [Jinshanibacter zhutongyuii]
ATGCCTACATCAACTACTACGCTAAAAATCGACAATAAGCTTAGAGAACGCATCAAAAAACTGGCAGATTCGCGCGATCG
TAGCCCACACTATTTGATGCTGGCAGCGATTACTGAATATATCGAACGTGAAGAAGCACAAGAAAGCTTTAAACAAGAAG
CTCTGGATTCCTGGAGAGAGTATCAAGAAACAGGCTTACATCTGACTGGTGATGAAGTAAAAACTTGGTTACGAGGCTGG
GGTACGGAGGCGGAAACGGATATTCCCGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References