Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-VagC
Location 2850200..2850870 Replicon chromosome
Accession NZ_CP034689
Organism Achromobacter spanius strain UQ283

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag ELS24_RS13205 Protein ID WP_127184357.1
Coordinates 2850469..2850870 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ELS24_RS13200 Protein ID WP_127184356.1
Coordinates 2850200..2850472 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELS24_RS13180 2845393..2847204 + 1812 WP_127184352.1 sulfoacetaldehyde acetyltransferase -
ELS24_RS13185 2847276..2848208 + 933 WP_127184353.1 bifunctional enoyl-CoA hydratase/phosphate acetyltransferase -
ELS24_RS13190 2848328..2848720 + 393 WP_127184354.1 nuclear transport factor 2 family protein -
ELS24_RS13195 2848740..2850140 + 1401 WP_205736967.1 FAD-dependent oxidoreductase -
ELS24_RS13200 2850200..2850472 + 273 WP_127184356.1 antitoxin Antitoxin
ELS24_RS13205 2850469..2850870 + 402 WP_127184357.1 type II toxin-antitoxin system VapC family toxin Toxin
ELS24_RS13210 2850944..2852476 - 1533 WP_127184358.1 PLP-dependent aminotransferase family protein -
ELS24_RS13215 2852589..2853416 - 828 WP_127184359.1 ABC transporter permease subunit -
ELS24_RS13220 2853409..2854239 - 831 WP_050446495.1 ATP-binding cassette domain-containing protein -
ELS24_RS13225 2854303..2855328 - 1026 WP_127184360.1 taurine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(16-63)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14324.49 Da        Isoelectric Point: 4.9408

>T116401 WP_127184357.1 NZ_CP034689:2850469-2850870 [Achromobacter spanius]
VSGYLLDTNIISALVRDPDGPAARHIERVGHQEICTSIVVAAELRYGCAKKGSPKLTAKVESLLETIPILPLDVPADAEY
GGIRAELEAEGKTIGANDMLIGAQAYALRLTLVTGNTREFERIRGLAVENWLI

Download         Length: 402 bp

>T116401 NZ_CP034689:2850469-2850870 [Achromobacter spanius]
GTGAGCGGCTATCTCTTGGACACCAACATCATCAGTGCCCTGGTTCGTGACCCCGATGGTCCCGCTGCGCGTCATATCGA
GCGGGTCGGTCATCAGGAAATTTGCACCAGCATCGTCGTGGCGGCCGAGTTGCGTTACGGCTGCGCCAAGAAAGGGTCTC
CCAAGCTGACAGCCAAGGTTGAGAGCTTGTTGGAGACGATTCCGATCCTGCCTCTCGATGTGCCGGCTGATGCCGAGTAC
GGCGGCATTCGCGCCGAGCTCGAAGCCGAAGGGAAAACCATCGGGGCCAACGATATGTTGATTGGTGCCCAGGCCTATGC
CTTGCGCCTTACGCTCGTGACCGGGAACACCCGAGAATTTGAACGTATCCGTGGCCTTGCCGTTGAAAATTGGCTCATCT
AA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10230.83 Da        Isoelectric Point: 4.8411

>AT116401 WP_127184356.1 NZ_CP034689:2850200-2850472 [Achromobacter spanius]
MPIPVIASRPREAKLFRNNRSQAVRIPAEFELPGDRVLIRREGTKLIIEPVAGPRNIVELLAQWRKDEPLGPDDQFPDIA
DMPPQPEDIL

Download         Length: 273 bp

>AT116401 NZ_CP034689:2850200-2850472 [Achromobacter spanius]
ATGCCCATTCCAGTTATCGCGTCCCGGCCACGCGAGGCCAAACTCTTCCGAAATAATCGGAGCCAGGCCGTCCGTATTCC
CGCTGAATTCGAACTGCCTGGCGACCGAGTATTGATCCGTCGTGAGGGCACCAAGCTCATCATTGAACCTGTGGCGGGAC
CGAGGAACATTGTTGAACTGCTGGCTCAATGGCGAAAGGATGAGCCGCTCGGGCCCGACGATCAATTTCCCGATATCGCT
GACATGCCGCCCCAGCCGGAGGACATTCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References