116399

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) FicTA/Fic(toxin)
Location 519888..521034 Replicon chromosome
Accession NZ_CP034689
Organism Achromobacter spanius strain UQ283

Toxin (Protein)


Gene name VbhT Uniprot ID -
Locus tag ELS24_RS02285 Protein ID WP_127183279.1
Coordinates 520120..521034 (+) Length 305 a.a.

Antitoxin (Protein)


Gene name VbhA Uniprot ID -
Locus tag ELS24_RS02280 Protein ID WP_205736951.1
Coordinates 519888..520094 (+) Length 69 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELS24_RS02250 515152..515496 - 345 WP_127183276.1 hypothetical protein -
ELS24_RS02260 517144..517893 + 750 WP_127186225.1 ParA family protein -
ELS24_RS02265 517890..519071 + 1182 WP_127183277.1 ParB/RepB/Spo0J family partition protein -
ELS24_RS02270 519136..519483 + 348 WP_127186226.1 H-NS histone family protein -
ELS24_RS02275 519540..519788 + 249 WP_127183278.1 hypothetical protein -
ELS24_RS02280 519888..520094 + 207 WP_205736951.1 antitoxin VbhA family protein Antitoxin
ELS24_RS02285 520120..521034 + 915 WP_127183279.1 Fic family protein Toxin
ELS24_RS02290 521410..521787 - 378 WP_127183280.1 hypothetical protein -
ELS24_RS02295 522298..522609 - 312 WP_127183281.1 hypothetical protein -
ELS24_RS02300 522701..522898 + 198 WP_127183282.1 hypothetical protein -
ELS24_RS02305 522909..523586 - 678 WP_127183283.1 SOS response-associated peptidase -
ELS24_RS02310 523689..524762 - 1074 WP_127183284.1 hypothetical protein -
ELS24_RS02315 524958..526022 + 1065 WP_127183285.1 IS110 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 511119..588969 77850


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(56-151)

Antitoxin

Antitoxin VbhA-like

(9-57)


Sequences

Toxin        


Download         Length: 305 a.a.        Molecular weight: 33899.15 Da        Isoelectric Point: 6.5060

>T116399 WP_127183279.1 NZ_CP034689:520120-521034 [Achromobacter spanius]
MAKYPINAQDPYVDPVSGVLRNRLAITDQAELDKVEATFAAVRSYELATDPIRGQFDLAHLQQIHQRLFGDVYDWAGKIR
TVDISKGTTRFASHEQITSYAPQITRPLSREGLLKGLAPDSFSERAGHYLGELNVLHPFREGNGRSIREFIGQLARDAGY
GIDWQGVDRGEMTKASIEAYQGDSQRMAHLIRASLREVDWEYALDLARAVAGDRAHVVQAIPGQSYEGVVIGLTERYLVQ
EQKGQAGEMVLHSRRALLNVDLALPGQMIGIRYPHGGVGLVEASLSQPERENSMQLQRDRGHER

Download         Length: 915 bp

>T116399 NZ_CP034689:520120-521034 [Achromobacter spanius]
ATGGCCAAATACCCCATCAACGCGCAAGATCCATACGTAGACCCTGTTTCCGGGGTTCTGCGTAATCGTCTTGCAATCAC
TGACCAGGCCGAACTGGACAAGGTGGAGGCAACCTTCGCCGCCGTGCGCTCTTATGAACTTGCTACGGACCCCATTCGGG
GGCAGTTTGACCTGGCGCACCTTCAACAGATCCATCAGCGGTTGTTCGGCGACGTCTATGACTGGGCGGGCAAGATCCGC
ACGGTCGACATTTCGAAGGGCACAACACGCTTCGCCAGCCACGAGCAGATCACAAGCTATGCGCCCCAGATCACGAGACC
ACTTTCGCGCGAAGGTCTCCTGAAGGGCCTTGCGCCTGATTCGTTCAGTGAGCGTGCTGGCCATTACTTGGGCGAGTTGA
ATGTGCTTCATCCCTTCCGGGAAGGCAATGGCAGAAGTATTCGGGAGTTCATCGGTCAGCTTGCAAGGGATGCAGGCTAC
GGCATTGACTGGCAGGGCGTTGATCGGGGCGAGATGACGAAGGCGTCGATCGAGGCCTATCAAGGAGACTCGCAGCGCAT
GGCGCACCTGATCCGCGCCAGTCTCCGAGAAGTTGACTGGGAATACGCTCTGGATCTGGCGAGGGCGGTGGCGGGCGATC
GCGCACACGTCGTTCAGGCTATTCCTGGGCAGAGTTATGAAGGCGTGGTTATCGGATTGACCGAGCGGTACCTGGTTCAA
GAACAAAAGGGCCAGGCTGGGGAGATGGTCCTGCACAGCCGTCGCGCGCTCCTCAACGTGGATCTCGCCCTTCCAGGGCA
GATGATCGGAATCCGCTATCCGCATGGTGGCGTCGGCTTGGTGGAAGCATCTCTGTCACAACCAGAGCGAGAGAACTCAA
TGCAGCTGCAACGCGACCGCGGGCATGAGCGGTGA

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7372.31 Da        Isoelectric Point: 9.1311

>AT116399 WP_205736951.1 NZ_CP034689:519888-520094 [Achromobacter spanius]
MLTSKDVIERRRAVANAVANQRLEGLEPDSRTVADLERAAAGELSVSDVLRTLHARIAAGEFRSSPAR

Download         Length: 207 bp

>AT116399 NZ_CP034689:519888-520094 [Achromobacter spanius]
ATGCTGACTTCTAAAGACGTGATAGAACGGCGCCGCGCTGTAGCAAATGCGGTGGCGAACCAGCGGCTGGAAGGCTTGGA
ACCCGACTCACGCACAGTTGCCGACCTTGAACGTGCAGCGGCTGGTGAATTGAGCGTGTCGGACGTCCTCCGTACCCTGC
ATGCCCGCATCGCCGCTGGCGAATTTCGTTCGTCGCCCGCTCGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References