116398

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Acetyltransf_4(toxin)
Location 5818442..5819881 Replicon chromosome
Accession NZ_CP034688
Organism Pseudomonas citronellolis strain WXP-4

Toxin (Protein)


Gene name - Uniprot ID W5IXK4
Locus tag ELR50_RS25940 Protein ID WP_009620564.1
Coordinates 5818442..5819011 (+) Length 190 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag ELR50_RS25945 Protein ID WP_269962594.1
Coordinates 5819021..5819881 (+) Length 287 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELR50_RS25935 (ELR50_25865) 5814714..5818190 - 3477 WP_269962593.1 hybrid sensor histidine kinase/response regulator -
ELR50_RS25940 (ELR50_25870) 5818442..5819011 + 570 WP_009620564.1 GNAT family protein Toxin
ELR50_RS25945 (ELR50_25875) 5819021..5819881 + 861 WP_269962594.1 AraC family transcriptional regulator Antitoxin
ELR50_RS25950 (ELR50_25880) 5820547..5822421 + 1875 WP_269962595.1 MFS transporter -
ELR50_RS25955 (ELR50_25885) 5822471..5822680 - 210 WP_009620558.1 cold-shock protein -
ELR50_RS25960 (ELR50_25890) 5822872..5823186 - 315 WP_009620556.1 quaternary ammonium compound efflux SMR transporter SugE -
ELR50_RS25965 (ELR50_25895) 5823330..5824274 - 945 WP_009620554.1 bile acid:sodium symporter family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(14-146)

Antitoxin

DNA binding HTH domain, AraC-type

(197-274)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 21064.37 Da        Isoelectric Point: 10.2120

>T116398 WP_009620564.1 NZ_CP034688:5818442-5819011 [Pseudomonas citronellolis]
MFRPSPITLQRGALRLEPMVEADVPDLVALAEANREALKFMSAPQRPDWYRNSLAEQREGRALPLVVRLGNQLVGTTRFM
DFLPALPACEIGGTWLDAAQHGTGLNASIKYLMLRQAFDNWKMVRVQLKTAASNLRSQRAIEKLGAVREGVLRNHRRLAG
GRLDDSVLYSITDLEWPQVKAALEAGFIG

Download         Length: 570 bp

>T116398 NZ_CP034688:5818442-5819011 [Pseudomonas citronellolis]
ATGTTCAGACCGTCACCCATCACCCTGCAGCGCGGTGCGCTGCGCCTGGAGCCCATGGTCGAGGCCGACGTGCCGGACCT
GGTGGCGCTGGCCGAGGCCAATCGCGAGGCGCTGAAGTTCATGAGCGCGCCGCAGCGCCCGGACTGGTACCGCAACAGCC
TCGCCGAGCAGCGCGAGGGCCGCGCCCTGCCGCTGGTGGTGCGCCTGGGCAACCAACTGGTGGGCACCACCCGCTTCATG
GATTTCCTTCCGGCGCTGCCGGCCTGCGAGATCGGTGGCACCTGGCTGGATGCGGCGCAGCACGGCACCGGGCTGAACGC
CAGCATCAAGTACCTGATGCTGCGCCAGGCCTTCGACAACTGGAAGATGGTCCGCGTGCAGCTGAAGACCGCCGCCAGTA
ACCTGCGCTCGCAGCGCGCCATCGAGAAGCTCGGCGCGGTGCGCGAGGGCGTGCTGCGCAACCACCGGCGCCTGGCCGGC
GGGCGCCTGGACGACAGCGTCCTCTACAGCATCACCGACCTGGAGTGGCCGCAGGTGAAGGCCGCCCTGGAAGCCGGCTT
CATCGGCTGA

Antitoxin


Download         Length: 287 a.a.        Molecular weight: 31569.91 Da        Isoelectric Point: 8.2157

>AT116398 WP_269962594.1 NZ_CP034688:5819021-5819881 [Pseudomonas citronellolis]
MPLDSAHGERTRFWRAQELGGLELLHARFIEQRFAPHVHEGFALVLIEQGAQRFRHRGAEHLAPSGSLVLINPDEVHTGS
KAHEAGWLYRGFYPEIGQVGSVLDELELGGRGLPTFDASVLHDPELSRAFLHVHRLLESNASSLERQTCWREALLLLFQC
HARVPEARPAGQEPQAVARARELLAARLVEPPSLEELAAAVNLSPFHFARVFRKATGLPPHAWIKQRRLEQARALLKGGC
GPASVAAQLGYADQSHLSRQFKQAYGVAPGEYRQACGRSGLPPGNL

Download         Length: 861 bp

>AT116398 NZ_CP034688:5819021-5819881 [Pseudomonas citronellolis]
ATGCCCCTCGACAGCGCCCATGGCGAGCGCACGCGCTTCTGGCGGGCCCAGGAACTGGGCGGCCTGGAGTTGCTGCACGC
GCGCTTCATCGAGCAGCGCTTCGCCCCCCACGTCCACGAAGGTTTCGCCCTGGTGCTGATCGAGCAGGGCGCCCAGCGCT
TCCGCCACCGCGGCGCCGAGCACCTGGCGCCCAGCGGCAGCCTGGTGCTGATCAATCCCGACGAGGTCCACACCGGCTCC
AAGGCCCATGAGGCGGGCTGGTTGTACCGTGGTTTCTATCCGGAGATCGGGCAGGTCGGCAGCGTGCTCGACGAGCTGGA
GCTGGGCGGCCGCGGCCTGCCGACCTTCGACGCCAGCGTGTTGCACGATCCCGAGCTGAGCCGTGCCTTCCTGCACGTGC
ACCGCCTGCTGGAATCCAATGCCAGCAGCCTGGAGCGCCAGACCTGCTGGCGCGAGGCATTGCTGTTGCTGTTCCAGTGC
CACGCGCGGGTGCCCGAGGCGCGCCCGGCCGGACAGGAACCCCAGGCGGTGGCCCGCGCCCGCGAGCTGCTGGCGGCCCG
GCTGGTCGAGCCGCCGTCGCTGGAAGAACTGGCGGCGGCGGTGAACCTGTCGCCCTTCCATTTCGCCCGGGTGTTCCGCA
AGGCCACCGGCCTGCCGCCCCACGCCTGGATCAAGCAACGCCGCCTGGAACAGGCCCGCGCGCTGCTCAAGGGCGGCTGC
GGGCCGGCCTCGGTGGCGGCGCAACTGGGCTACGCCGACCAGAGTCACCTGAGTCGCCAGTTCAAGCAGGCCTACGGCGT
GGCGCCGGGGGAATACCGCCAGGCTTGCGGACGTTCCGGCCTGCCACCCGGCAACCTGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1A5DB72

Antitoxin

Source ID Structure

References