Detailed information of TA system TA116397

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Xre(antitoxin)
• Location: 5805117..5806256
• Replicon: chromosome
• Accession: NZ_CP034688
• Organism: Pseudomonas citronellolis strain WXP-4

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: ELR50_RS25900
• Protein ID: WP_058072905.1
• Coordinates: 5805486..5806256 (+)
• Length: 257 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: A0A1A5D9R9
• Locus tag: ELR50_RS25895
• Protein ID: WP_043271094.1
• Coordinates: 5805117..5805485 (+)
• Length: 123 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ELR50_RS25860 (ELR50_25790)	5800312..5801148	-	837	WP_269962588.1	5'-nucleotidase, lipoprotein e(P4) family	-
ELR50_RS25865 (ELR50_25795)	5801442..5802491	+	1050	WP_064583933.1	diguanylate cyclase	-
ELR50_RS25870 (ELR50_25800)	5802479..5802850	-	372	WP_269962589.1	hypothetical protein	-
ELR50_RS25875 (ELR50_25805)	5802942..5803283	-	342	WP_009620588.1	carboxymuconolactone decarboxylase family protein	-
ELR50_RS25880 (ELR50_25810)	5803355..5803837	-	483	WP_269962590.1	GreA/GreB family elongation factor	-
ELR50_RS25885 (ELR50_25815)	5803966..5804397	+	432	WP_052267763.1	hypothetical protein	-
ELR50_RS25890 (ELR50_25820)	5804404..5804838	-	435	WP_269962591.1	RcnB family protein	-
ELR50_RS25895 (ELR50_25825)	5805117..5805485	+	369	WP_043271094.1	DUF2384 domain-containing protein	Antitoxin
ELR50_RS25900 (ELR50_25830)	5805486..5806256	+	771	WP_058072905.1	RES family NAD+ phosphorylase	Toxin
ELR50_RS25905 (ELR50_25835)	5806332..5806538	+	207	WP_058490861.1	hypothetical protein	-
ELR50_RS25910 (ELR50_25840)	5807063..5808427	+	1365	WP_269964293.1	DNA recombination protein RmuC	-
ELR50_RS25915 (ELR50_25845)	5808926..5809813	-	888	WP_009620572.1	metal-dependent hydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (69-212)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (71-120)

Sequences

Toxin

Protein

• Length: 257 a.a.
• Molecular weight: 28892.06 Da
• Isoelectric Point: 7.0428

>T116397 WP_058072905.1 NZ_CP034688:5805486-5806256 [Pseudomonas citronellolis]
MALDAGAELWRECRGEQAIAPLRGKLVRLVESQEQVATLQLVDTLEEQALLEELIETSKPHLPPSTETLHYLLKTPFRYP
PLRWGSRFGRRHEPSLFYAALRLETAMAEAAYYRFVLWEGMASPPPSGRILSEHASFEARFQVQRGIRLQAPPFDSYAER
LQDPRDYRLTQALGSAMRAAAVEAFEYRSARCPEGGLNAALFVPSAFVDKRPRNLMPWLCETTADYVAFKHAQVPGAPRL
FPRTGFLVEGDLPHPA

Nucleotide

• Length: 771 bp

>T116397 NZ_CP034688:5805486-5806256 [Pseudomonas citronellolis]
ATGGCTCTCGACGCCGGCGCCGAACTGTGGCGCGAATGCCGGGGCGAGCAGGCCATCGCCCCGCTGCGGGGCAAGCTGGT
GCGCCTGGTGGAGAGCCAGGAGCAGGTCGCGACCCTGCAACTGGTGGATACCCTGGAGGAGCAGGCCTTGCTGGAAGAGC
TGATCGAGACCAGCAAGCCGCACCTGCCGCCGTCCACCGAAACCCTGCACTACCTGCTCAAGACGCCGTTCCGCTACCCG
CCGCTGCGCTGGGGCTCGCGCTTCGGCCGGCGCCACGAACCCAGCCTGTTCTACGCCGCGTTGCGCCTGGAGACGGCCAT
GGCCGAGGCGGCCTATTACCGCTTCGTGCTCTGGGAGGGCATGGCCAGTCCGCCGCCCAGCGGGCGCATCCTTTCCGAGC
ACGCTTCCTTCGAGGCGCGTTTCCAGGTGCAACGGGGCATACGCCTGCAGGCGCCGCCCTTCGACAGCTATGCCGAGCGC
CTGCAGGACCCGCGGGACTACCGCCTGACCCAGGCGCTGGGCAGCGCCATGCGCGCTGCCGCGGTGGAGGCCTTCGAATA
CCGCTCGGCGCGCTGCCCGGAAGGTGGGCTGAATGCCGCGCTCTTCGTGCCTTCGGCCTTCGTCGACAAGCGCCCGCGCA
ACCTCATGCCCTGGTTGTGCGAGACCACCGCCGACTACGTGGCCTTCAAGCATGCCCAGGTGCCGGGGGCGCCGCGGCTG
TTCCCACGCACGGGATTCCTGGTCGAGGGCGACCTGCCGCACCCGGCGTGA

Antitoxin

Protein

• Length: 123 a.a.
• Molecular weight: 13395.70 Da
• Isoelectric Point: 10.8284

>AT116397 WP_043271094.1 NZ_CP034688:5805117-5805485 [Pseudomonas citronellolis]
MSALIRETPSADLVLAKAVLAAREQLGMTQQELAAIVGVDRSAVSRWKSGGLRVGSKTGELALLLVRVYRALFALFGGNL
EDMRHFLRTPNRHLSGVPLQRMEQVQGLVQVVEYLDAIRGKI

Nucleotide

• Length: 369 bp

>AT116397 NZ_CP034688:5805117-5805485 [Pseudomonas citronellolis]
ATGAGCGCACTGATCCGGGAAACTCCGTCGGCCGATCTGGTCCTGGCCAAGGCGGTACTAGCTGCCCGTGAGCAACTGGG
CATGACGCAGCAGGAGCTGGCCGCCATCGTCGGCGTCGACCGCAGCGCGGTGAGCCGCTGGAAGAGCGGCGGCCTGCGGG
TGGGCAGCAAGACCGGCGAGCTGGCGCTGCTGCTGGTGCGGGTATACCGCGCGCTCTTCGCCCTGTTCGGCGGCAACCTG
GAGGACATGCGCCACTTCCTGCGCACCCCCAACCGCCACCTGAGCGGTGTGCCGCTGCAGCGGATGGAGCAGGTGCAGGG
CCTGGTGCAGGTGGTCGAGTACCTCGACGCCATCCGGGGCAAGATCTGA

Structures

Antitoxin

• AlphaFold DB: A0A1A5D9R9