Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 3163189..3164851 Replicon chromosome
Accession NZ_CP034688
Organism Pseudomonas citronellolis strain WXP-4

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag ELR50_RS14090 Protein ID WP_269964184.1
Coordinates 3163189..3164025 (+) Length 279 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag ELR50_RS14095 Protein ID WP_058071792.1
Coordinates 3164030..3164851 (+) Length 274 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELR50_RS14065 (ELR50_13975) 3159202..3160044 + 843 WP_269964259.1 ABC transporter ATP-binding protein -
ELR50_RS14070 (ELR50_13980) 3160130..3161062 + 933 Protein_2774 ABC transporter substrate-binding protein -
ELR50_RS14075 (ELR50_13985) 3161079..3161852 + 774 WP_043315312.1 ABC transporter permease -
ELR50_RS14080 (ELR50_13990) 3161863..3162624 + 762 WP_269964183.1 SDR family oxidoreductase -
ELR50_RS14085 (ELR50_13995) 3162636..3163169 + 534 WP_074986018.1 cupin domain-containing protein -
ELR50_RS14090 (ELR50_14000) 3163189..3164025 + 837 WP_269964184.1 alpha/beta fold hydrolase Toxin
ELR50_RS14095 (ELR50_14005) 3164030..3164851 + 822 WP_058071792.1 IclR family transcriptional regulator Antitoxin
ELR50_RS14100 (ELR50_14010) 3164848..3165645 + 798 WP_269964185.1 SDR family oxidoreductase -
ELR50_RS14105 (ELR50_14015) 3165638..3167320 + 1683 WP_269964186.1 thiamine pyrophosphate-binding protein -
ELR50_RS14110 (ELR50_14020) 3167331..3168134 + 804 WP_058071795.1 aspartate dehydrogenase -
ELR50_RS14115 (ELR50_14025) 3168145..3169632 + 1488 WP_269964187.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(40-268)

Antitoxin

Transcription regulator IclR, C-terminal

(133-254)


Sequences

Toxin        


Download         Length: 279 a.a.        Molecular weight: 29294.81 Da        Isoelectric Point: 7.3290

>T116392 WP_269964184.1 NZ_CP034688:3163189-3164025 [Pseudomonas citronellolis]
MSTAAAWQADLERDFPQRLARHGEVVSAWREAGAADAPALVLLHGIGSGAASWLPLAQCLKARARLIAWDAPGYGESTPL
AEAAPRAEAYMQRLRELLDALDVQRCVLLGHSLGALTALALANAEPRRVARLLLLSPARGYGARPAEGEAVRSRRLAALA
SEGIAGLAERRAPAMLGASPGAEALAWVRWNMARLKPHGYRQAVELLCGDDLLRLGRPPVPVEVLCGSEDGITPPAACRE
VAAALAAPFQLIPGAGHASPIECPEALAGHLVRILDKD

Download         Length: 837 bp

>T116392 NZ_CP034688:3163189-3164025 [Pseudomonas citronellolis]
ATGAGCACGGCGGCCGCCTGGCAGGCCGACCTGGAACGCGACTTCCCGCAGCGCCTGGCGCGCCACGGCGAGGTCGTCAG
CGCCTGGCGCGAAGCCGGCGCGGCCGACGCCCCGGCGCTGGTGCTGCTGCACGGCATCGGCTCAGGCGCGGCCTCCTGGC
TGCCGCTGGCGCAGTGCCTGAAGGCGCGCGCGCGGCTCATCGCCTGGGACGCCCCCGGCTACGGCGAATCCACGCCGCTG
GCCGAGGCCGCGCCGCGGGCGGAAGCCTACATGCAGCGCCTGCGCGAGCTGCTGGACGCGCTGGACGTGCAGCGCTGCGT
GCTGCTCGGCCATTCCCTGGGCGCGCTGACCGCCCTCGCCCTGGCCAACGCCGAGCCGCGGCGCGTTGCCCGCCTGCTGC
TGCTGAGCCCGGCGCGCGGCTACGGCGCGCGCCCGGCCGAAGGCGAAGCGGTACGCAGCCGGCGCCTGGCCGCTCTGGCC
AGCGAGGGCATCGCCGGCCTCGCCGAACGCCGCGCCCCGGCCATGCTCGGCGCCAGCCCCGGCGCCGAGGCGCTGGCCTG
GGTGCGCTGGAACATGGCGCGGCTCAAGCCCCACGGCTACCGCCAGGCGGTGGAGCTGCTGTGCGGCGACGACCTGCTGC
GCCTGGGCCGCCCGCCGGTGCCCGTCGAGGTGCTGTGCGGCAGCGAGGACGGCATCACCCCGCCGGCCGCCTGCCGCGAA
GTCGCCGCGGCGCTGGCGGCGCCCTTCCAGCTAATCCCCGGCGCCGGCCACGCCAGCCCCATCGAATGCCCCGAAGCCCT
GGCCGGACACCTCGTTCGCATCCTCGACAAGGACTGA

Antitoxin


Download         Length: 274 a.a.        Molecular weight: 30315.89 Da        Isoelectric Point: 6.7546

>AT116392 WP_058071792.1 NZ_CP034688:3164030-3164851 [Pseudomonas citronellolis]
MSTDTLTENQERYMVPGLERGLTLLGEFTRHDRTLTAPELARRLQLPRTTIFRLLATLEALGFVTRSGNEYRLGMAVLRL
GFEYLASLELTELGQPILRRLCDAIGYSCNLVVRDGRNIVYVAKISPPSILTSAVNVGTRLPAHATVLGRILLEDLDLAA
LRELYPEKQLERFSEGTPRSTEELFDLVQNDRLRGYALSEGFFEASISTVAAPVRDHTGRVCAAMGVTIPATRIAEHLLE
PLVRQVRNSAEELSGLLGHMPNPNVLSLQRVHS

Download         Length: 822 bp

>AT116392 NZ_CP034688:3164030-3164851 [Pseudomonas citronellolis]
ATGAGTACCGACACCCTCACCGAAAACCAGGAACGCTACATGGTTCCGGGGCTGGAACGCGGCCTGACGCTGCTGGGCGA
GTTCACCCGCCACGACCGCACCCTCACCGCCCCGGAACTGGCGCGCCGCCTGCAACTGCCGCGCACCACCATCTTCCGCC
TGCTGGCCACCCTCGAGGCCCTGGGCTTCGTCACCCGCAGCGGCAACGAATACCGCCTGGGCATGGCGGTGCTGCGCCTG
GGCTTCGAATACCTGGCCTCGCTGGAACTCACCGAGCTGGGCCAGCCGATCCTGCGCCGCCTGTGCGACGCCATCGGCTA
CTCCTGCAACCTGGTGGTGCGCGACGGGCGCAACATCGTCTACGTGGCGAAGATCTCGCCGCCGTCGATCCTCACCAGCG
CGGTCAACGTCGGCACCCGCCTGCCGGCCCACGCCACCGTGCTCGGGCGCATCCTCCTGGAAGACCTGGACCTCGCCGCG
CTGCGCGAGCTGTATCCGGAGAAGCAACTGGAGCGCTTCTCCGAGGGCACCCCGCGCAGCACCGAGGAACTCTTCGACCT
GGTGCAGAACGACCGCCTGCGCGGCTACGCGCTGAGCGAAGGCTTCTTCGAGGCGAGCATCTCCACCGTCGCCGCGCCGG
TGCGCGACCACACCGGGCGCGTCTGCGCCGCCATGGGCGTGACCATCCCCGCCACGCGCATCGCCGAGCACCTGCTGGAG
CCGCTGGTGCGCCAGGTGCGCAACAGCGCCGAGGAACTCTCCGGCCTGCTCGGGCACATGCCCAACCCCAACGTCCTGTC
GCTGCAGAGGGTGCATTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References