Detailed information of TA system TA116387

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 1305671..1306224
• Replicon: chromosome
• Accession: NZ_CP034688
• Organism: Pseudomonas citronellolis strain WXP-4

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: ELR50_RS05605
• Protein ID: WP_269963435.1
• Coordinates: 1305671..1305946 (-)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: ELR50_RS05610
• Protein ID: WP_256511720.1
• Coordinates: 1305946..1306224 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ELR50_RS05580 (ELR50_05545)	1301436..1302494	-	1059	WP_269963431.1	agmatine deiminase family protein	-
ELR50_RS05585 (ELR50_05550)	1302627..1303493	+	867	WP_269963432.1	LysR substrate-binding domain-containing protein	-
ELR50_RS05590 (ELR50_05555)	1303505..1304170	-	666	WP_269963433.1	M24 family metallopeptidase	-
ELR50_RS05595 (ELR50_05560)	1304350..1305165	+	816	WP_269963434.1	protein phosphatase 2C domain-containing protein	-
ELR50_RS05600 (ELR50_05565)	1305197..1305622	-	426	WP_009619483.1	VOC family protein	-
ELR50_RS05605 (ELR50_05570)	1305671..1305946	-	276	WP_269963435.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ELR50_RS05610 (ELR50_05575)	1305946..1306224	-	279	WP_256511720.1	ribbon-helix-helix domain-containing protein	Antitoxin
ELR50_RS05615	1306591..1306827	+	237	Protein_1114	AAA family ATPase	-
ELR50_RS05620	1306918..1307361	+	444	WP_269964222.1	NUDIX domain-containing protein	-
ELR50_RS05625 (ELR50_05585)	1307961..1309097	+	1137	WP_269963436.1	FMNH2-dependent alkanesulfonate monooxygenase	-
ELR50_RS05630 (ELR50_05590)	1309184..1310713	+	1530	WP_269963437.1	FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (10-47)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10570.20 Da
• Isoelectric Point: 10.5619

>T116387 WP_269963435.1 NZ_CP034688:c1305946-1305671 [Pseudomonas citronellolis]
MALQWTSKALSDLARLHEFLAPVNRSAAARTVQQLVAAPAVLLTNPRLGERLDEFAPRDVRRLLVGHYEMRYEIRGSDIH
LLRIWHTREER

Nucleotide

• Length: 276 bp

>T116387 NZ_CP034688:c1305946-1305671 [Pseudomonas citronellolis]
ATGGCGTTGCAGTGGACGAGCAAGGCCTTGTCCGATCTGGCACGGCTCCATGAGTTTCTCGCTCCGGTGAACCGGTCTGC
GGCGGCCCGCACCGTCCAGCAATTGGTCGCCGCGCCGGCTGTTCTGCTGACCAACCCACGCCTCGGTGAGCGCCTGGATG
AGTTCGCGCCGCGTGATGTCCGGCGGCTTCTGGTTGGCCATTACGAGATGCGCTACGAGATACGGGGCTCCGACATCCAT
CTGCTTCGCATATGGCATACCCGCGAAGAGCGCTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10361.61 Da
• Isoelectric Point: 4.6787

>AT116387 WP_256511720.1 NZ_CP034688:c1306224-1305946 [Pseudomonas citronellolis]
MATTCKTRSVTAHVPVELAERVDEIAERLERSKNWIVKQALSAWLDQEDERSRLTREALADVDAGRVIDHQSVQAWADSL
DSDTPLPLPVPR

Nucleotide

• Length: 279 bp

>AT116387 NZ_CP034688:c1306224-1305946 [Pseudomonas citronellolis]
ATGGCCACGACCTGCAAGACCCGCTCGGTCACCGCTCACGTTCCCGTCGAACTGGCGGAGCGCGTGGATGAAATCGCCGA
GCGCCTGGAGCGTTCGAAGAACTGGATCGTCAAGCAGGCCTTGTCCGCCTGGCTTGATCAGGAAGACGAGCGTAGCCGTC
TGACCCGCGAGGCCTTGGCCGATGTGGATGCCGGCCGGGTAATAGATCACCAGTCCGTCCAGGCCTGGGCGGACAGCCTG
GACTCCGACACGCCGCTACCGCTGCCGGTACCGCGCTGA