116379

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 510679..512056 Replicon chromosome
Accession NZ_CP034683
Organism Rheinheimera sp. LHK132

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag EK374_RS02355 Protein ID WP_127019772.1
Coordinates 510679..511671 (-) Length 331 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID -
Locus tag EK374_RS02360 Protein ID WP_127019774.1
Coordinates 511652..512056 (-) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EK374_RS02345 506565..506879 - 315 WP_127019768.1 helix-turn-helix domain-containing protein -
EK374_RS02350 507321..510464 + 3144 WP_127019770.1 DEAD/DEAH box helicase -
EK374_RS02355 510679..511671 - 993 WP_127019772.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
EK374_RS02360 511652..512056 - 405 WP_127019774.1 S-adenosylhomocysteine hydrolase Antitoxin
EK374_RS02365 512431..513291 - 861 WP_127019776.1 YicC family protein -
EK374_RS02370 513494..514207 + 714 WP_127019779.1 ribonuclease PH -
EK374_RS02375 514241..514885 + 645 WP_127019781.1 orotate phosphoribosyltransferase -
EK374_RS02380 514913..515284 + 372 WP_127019783.1 diacylglycerol kinase -
EK374_RS02385 515523..516116 - 594 WP_127019785.1 nucleoid occlusion factor SlmA -
EK374_RS02390 516135..516593 - 459 WP_127019787.1 dUTP diphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(34-303)

Antitoxin

Protein of unknown function DUF6088

(7-130)


Sequences

Toxin        


Download         Length: 331 a.a.        Molecular weight: 37596.71 Da        Isoelectric Point: 4.6608

>T116379 WP_127019772.1 NZ_CP034683:c511671-510679 [Rheinheimera sp. LHK132]
VSTKFDSSLFVDVANALGLGNTAIVEKDYYVVQLLQQISALELEYHHIVFSGGTALAKSAIKTYRMSEDVDLKLVPKPAF
SDLISRNAKRNARKAAKQLVESVIAQSEIFSVETAPLVLDEYRYFSFEIRYPQEYQQAPCLRPFIKLEFIESDLLSASEP
RSIQSIFSRMLKSDVEINQLSCAAIIETQAEKLLSMMRRTASVERNSERDDDETLVRHIYDTYHIQLAQPSDIEQLGALV
AKAIRTDVERYGNQHPQMVESPIEELRFGLQLLADNPKFEQRYNSYVSPMVYAETPTQWLEALTVFIKLSNDVLDYVEQQ
FDDLLAKVSS

Download         Length: 993 bp

>T116379 NZ_CP034683:c511671-510679 [Rheinheimera sp. LHK132]
GTGTCAACGAAGTTCGATAGCTCACTCTTTGTCGATGTTGCGAATGCTTTAGGGCTTGGCAACACTGCCATTGTTGAAAA
AGACTATTACGTAGTGCAATTGCTGCAGCAGATATCTGCACTTGAACTCGAATATCACCACATCGTGTTCTCTGGTGGAA
CAGCACTGGCGAAATCTGCAATCAAAACCTATCGCATGTCTGAAGACGTCGATCTAAAGCTGGTCCCAAAGCCAGCTTTT
TCCGACCTCATCTCTCGAAATGCCAAAAGAAATGCACGCAAGGCCGCTAAGCAACTGGTTGAGTCAGTTATTGCACAGAG
TGAAATTTTTTCTGTTGAAACTGCGCCTCTAGTGTTGGATGAATATAGATATTTCAGTTTCGAAATCCGTTACCCACAGG
AGTATCAGCAAGCGCCCTGTTTGCGTCCATTTATCAAACTGGAGTTTATCGAATCTGATTTACTCAGCGCCTCTGAGCCA
CGGAGTATTCAGTCTATTTTTTCGCGCATGCTGAAAAGTGATGTCGAGATTAACCAGTTATCCTGCGCTGCGATTATTGA
GACACAAGCCGAAAAACTGCTGTCAATGATGCGCAGAACAGCTAGTGTAGAGCGCAACAGCGAACGGGATGATGACGAGA
CCTTAGTTCGGCATATCTACGATACTTACCATATCCAGCTCGCCCAACCTTCAGATATCGAGCAACTGGGTGCACTTGTG
GCTAAAGCAATCCGCACAGATGTTGAGCGCTACGGTAATCAACATCCACAAATGGTTGAATCCCCTATTGAAGAGTTACG
CTTCGGATTGCAGCTTTTAGCTGACAACCCTAAGTTCGAGCAGCGATACAACAGCTATGTTAGCCCTATGGTGTATGCTG
AAACCCCCACTCAATGGCTGGAGGCGTTAACTGTTTTTATAAAGCTATCGAATGACGTGTTGGATTATGTGGAGCAACAA
TTTGATGACCTACTTGCGAAAGTAAGCAGTTAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15178.54 Da        Isoelectric Point: 10.8536

>AT116379 WP_127019774.1 NZ_CP034683:c512056-511652 [Rheinheimera sp. LHK132]
MTIQDRIQTRVKRSKRSVFLRSDFTDIADYDQVGRGLRSLVREGLLLKIGYGLYVRARINRITGQLMPDNPAGNDGVMIE
AMERLGVDYQLDDLSLKNLSGESTQIPANVKIIPKSSRFTRKIAVGKQRVNEVR

Download         Length: 405 bp

>AT116379 NZ_CP034683:c512056-511652 [Rheinheimera sp. LHK132]
ATGACGATACAAGACAGAATACAAACCAGAGTGAAGCGCTCTAAGCGTTCTGTTTTTCTACGTTCTGATTTTACTGATAT
CGCTGATTATGACCAGGTTGGCCGTGGGCTCAGAAGCCTGGTACGCGAAGGCTTGTTATTGAAAATTGGCTACGGCCTGT
ATGTGCGCGCCAGAATCAATCGCATCACTGGTCAGCTAATGCCGGACAACCCTGCCGGTAATGACGGTGTAATGATAGAG
GCTATGGAAAGGTTAGGTGTTGATTATCAACTTGATGACTTGTCTCTGAAAAATTTGTCAGGCGAAAGCACTCAAATTCC
GGCAAATGTGAAGATTATTCCTAAGAGTTCGCGCTTTACCCGCAAGATTGCGGTAGGGAAACAGCGTGTCAACGAAGTTC
GATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References