Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1340467..1341131 Replicon chromosome
Accession NZ_CP034670
Organism Eikenella corrodens strain KCOM 3110

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag ELB75_RS06735 Protein ID WP_126983266.1
Coordinates 1340467..1340895 (-) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ELB75_RS06740 Protein ID WP_126983267.1
Coordinates 1340892..1341131 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ELB75_RS06710 1335531..1335770 - 240 WP_049258047.1 DNA-binding transcriptional regulator Fis -
ELB75_RS06715 1335873..1336877 - 1005 WP_126983262.1 tRNA dihydrouridine synthase DusB -
ELB75_RS06720 1337073..1337351 - 279 WP_126983263.1 hypothetical protein -
ELB75_RS06725 1337363..1339852 - 2490 WP_126983264.1 TraC family protein -
ELB75_RS06730 1339911..1340342 - 432 WP_126983265.1 single-stranded DNA-binding protein -
ELB75_RS06735 1340467..1340895 - 429 WP_126983266.1 type II toxin-antitoxin system VapC family toxin Toxin
ELB75_RS06740 1340892..1341131 - 240 WP_126983267.1 hypothetical protein Antitoxin
ELB75_RS06745 1341269..1341853 - 585 WP_126983268.1 hypothetical protein -
ELB75_RS06750 1341961..1342473 - 513 WP_126983269.1 hypothetical protein -
ELB75_RS06755 1342488..1343582 - 1095 WP_164726833.1 DUF1845 family protein -
ELB75_RS06760 1343786..1345477 - 1692 WP_206501440.1 hypothetical protein -
ELB75_RS06765 1345449..1345946 - 498 WP_064089673.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-127)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15235.50 Da        Isoelectric Point: 5.1358

>T116353 WP_126983266.1 NZ_CP034670:c1340895-1340467 [Eikenella corrodens]
MILVDTNVISETLRQQPDPAVVRWMDAQSIETLYLSAVTVAELRYGIAVLPEGRKRQVLHNGLEQSVLPLFEGRILPFDG
AAAISYAELMAAARRRGRGVSAADGYIAATAHAAGLMVATRDTSPFEAVGLAVVNPWLFDAG

Download         Length: 429 bp

>T116353 NZ_CP034670:c1340895-1340467 [Eikenella corrodens]
ATGATTTTAGTCGATACCAACGTCATTTCCGAGACTCTTCGGCAGCAGCCCGATCCTGCCGTTGTGCGCTGGATGGATGC
CCAGTCGATCGAAACGCTTTATCTGTCGGCCGTGACGGTGGCCGAACTGCGCTACGGCATTGCCGTACTGCCGGAAGGCA
GGAAGCGGCAAGTGCTGCATAACGGGCTGGAGCAGTCGGTACTACCCCTGTTCGAGGGGCGTATCCTGCCTTTTGATGGC
GCAGCAGCGATATCGTATGCCGAATTGATGGCTGCCGCCCGCCGTCGGGGCCGGGGGGTGTCGGCAGCCGACGGCTATAT
TGCCGCCACCGCCCATGCCGCCGGTTTGATGGTGGCAACCCGGGATACCTCTCCGTTCGAGGCGGTCGGTTTGGCGGTAG
TCAATCCCTGGCTGTTTGATGCCGGGTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8540.71 Da        Isoelectric Point: 10.1954

>AT116353 WP_126983267.1 NZ_CP034670:c1341131-1340892 [Eikenella corrodens]
MAAITIRNLSDETHRALKARAASAGRSTEAEIRLILEQAARPERRIKLGSLLTGLGRQAGGVDLETVRDPSVTQPVSYE

Download         Length: 240 bp

>AT116353 NZ_CP034670:c1341131-1340892 [Eikenella corrodens]
ATGGCTGCCATCACCATCCGCAACCTGTCCGACGAAACCCACCGCGCCCTGAAAGCCCGGGCGGCCTCCGCCGGGCGCAG
CACCGAGGCGGAAATCCGTCTGATTCTGGAGCAGGCCGCCCGTCCCGAGCGGCGGATTAAATTGGGCTCGCTGCTGACCG
GTTTGGGCCGGCAGGCCGGCGGGGTGGATTTGGAAACCGTCCGTGATCCTTCCGTCACACAGCCGGTGTCATACGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References