Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4494049..4494410 Replicon chromosome
Accession NZ_CP034657
Organism Xanthomonas vasicola strain NCPPB 902

Toxin (Protein)


Gene name EcnB Uniprot ID A0A836P2V1
Locus tag NX08_RS20800 Protein ID WP_010374872.1
Coordinates 4494049..4494183 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A836P2N2
Locus tag NX08_RS20805 Protein ID WP_010374875.1
Coordinates 4494258..4494410 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NX08_RS20785 4491074..4492132 - 1059 WP_164722168.1 MBL fold metallo-hydrolase -
NX08_RS20790 4492148..4493437 - 1290 WP_010379241.1 tryptophan--tRNA ligase -
NX08_RS20795 4493609..4493818 - 210 WP_017117799.1 CsbD family protein -
NX08_RS20800 4494049..4494183 - 135 WP_010374872.1 entericidin A/B family lipoprotein Toxin
NX08_RS20805 4494258..4494410 - 153 WP_010374875.1 entericidin A/B family lipoprotein Antitoxin
NX08_RS20810 4494518..4495441 - 924 WP_010379236.1 arginase -
NX08_RS20815 4495749..4496201 + 453 WP_010374879.1 roadblock/LC7 domain-containing protein -
NX08_RS20820 4496265..4496624 + 360 WP_010374881.1 hypothetical protein -
NX08_RS20825 4496722..4497639 + 918 WP_039441006.1 hypothetical protein -
NX08_RS20830 4497636..4498178 + 543 WP_017117801.1 GTPase -
NX08_RS20840 4498657..4499340 + 684 WP_010374890.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4475.37 Da        Isoelectric Point: 10.2040

>T116298 WP_010374872.1 NZ_CP034657:c4494183-4494049 [Xanthomonas vasicola]
MKRAIVLLVLSMLSVGMLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T116298 NZ_CP034657:c4494183-4494049 [Xanthomonas vasicola]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTCGGTATGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5065.02 Da        Isoelectric Point: 8.7942

>AT116298 WP_010374875.1 NZ_CP034657:c4494410-4494258 [Xanthomonas vasicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT116298 NZ_CP034657:c4494410-4494258 [Xanthomonas vasicola]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGTAAGGACATGCAGGGTGCAGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A836P2V1

Antitoxin

Source ID Structure
AlphaFold DB A0A836P2N2

References