116295

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3785824..3786185 Replicon chromosome
Accession NZ_CP034655
Organism Xanthomonas campestris pv. musacearum NCPPB 4379

Toxin (Protein)


Gene name EcnB Uniprot ID A0A836P2V1
Locus tag KWO_RS17500 Protein ID WP_010374872.1
Coordinates 3785824..3785958 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A836P2N2
Locus tag KWO_RS17505 Protein ID WP_010374875.1
Coordinates 3786033..3786185 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KWO_RS17485 3782848..3783906 - 1059 Protein_3207 MBL fold metallo-hydrolase -
KWO_RS17490 3783922..3785211 - 1290 WP_010379241.1 tryptophan--tRNA ligase -
KWO_RS17495 3785383..3785592 - 210 WP_010374870.1 CsbD family protein -
KWO_RS17500 3785824..3785958 - 135 WP_010374872.1 entericidin A/B family lipoprotein Toxin
KWO_RS17505 3786033..3786185 - 153 WP_010374875.1 entericidin A/B family lipoprotein Antitoxin
KWO_RS17510 3786293..3787216 - 924 WP_010379236.1 arginase -
KWO_RS17515 3787539..3787991 + 453 WP_010374879.1 roadblock/LC7 domain-containing protein -
KWO_RS17520 3788055..3788414 + 360 WP_010374881.1 hypothetical protein -
KWO_RS17525 3788512..3789429 + 918 WP_017112292.1 hypothetical protein -
KWO_RS17530 3789426..3789968 + 543 WP_010374885.1 GTPase -
KWO_RS17540 3790447..3791130 + 684 WP_010374890.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4475.37 Da        Isoelectric Point: 10.2040

>T116295 WP_010374872.1 NZ_CP034655:c3785958-3785824 [Xanthomonas campestris pv. musacearum NCPPB 4379]
MKRAIVLLVLSMLSVGMLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T116295 NZ_CP034655:c3785958-3785824 [Xanthomonas campestris pv. musacearum NCPPB 4379]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTCGGTATGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5065.02 Da        Isoelectric Point: 8.7942

>AT116295 WP_010374875.1 NZ_CP034655:c3786185-3786033 [Xanthomonas campestris pv. musacearum NCPPB 4379]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT116295 NZ_CP034655:c3786185-3786033 [Xanthomonas campestris pv. musacearum NCPPB 4379]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGTAAGGACATGCAGGGTGCAGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A836P2V1

Antitoxin

Source ID Structure
AlphaFold DB A0A836P2N2

References