116292

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4513964..4514325 Replicon chromosome
Accession NZ_CP034653
Organism Xanthomonas vasicola pv. arecae strain NCPPB 2649

Toxin (Protein)


Gene name EcnB Uniprot ID A0A836P2V1
Locus tag NX80_RS20945 Protein ID WP_010374872.1
Coordinates 4513964..4514098 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A836P2N2
Locus tag NX80_RS20950 Protein ID WP_010374875.1
Coordinates 4514173..4514325 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NX80_RS20930 4510989..4512023 - 1035 WP_193588641.1 MBL fold metallo-hydrolase -
NX80_RS20935 4512063..4513352 - 1290 WP_010379241.1 tryptophan--tRNA ligase -
NX80_RS20940 4513524..4513733 - 210 WP_017117799.1 CsbD family protein -
NX80_RS20945 4513964..4514098 - 135 WP_010374872.1 entericidin A/B family lipoprotein Toxin
NX80_RS20950 4514173..4514325 - 153 WP_010374875.1 entericidin A/B family lipoprotein Antitoxin
NX80_RS20955 4514433..4515356 - 924 WP_047698282.1 arginase -
NX80_RS20965 4515506..4516593 + 1088 WP_126925254.1 IS3 family transposase -
NX80_RS20975 4516878..4517330 + 453 WP_047699727.1 roadblock/LC7 domain-containing protein -
NX80_RS20980 4517394..4517753 + 360 WP_010374881.1 hypothetical protein -
NX80_RS20985 4517851..4518768 + 918 WP_017112292.1 hypothetical protein -
NX80_RS20990 4518765..4519307 + 543 WP_010374885.1 GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4475.37 Da        Isoelectric Point: 10.2040

>T116292 WP_010374872.1 NZ_CP034653:c4514098-4513964 [Xanthomonas vasicola pv. arecae]
MKRAIVLLVLSMLSVGMLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T116292 NZ_CP034653:c4514098-4513964 [Xanthomonas vasicola pv. arecae]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTCGGTATGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5065.02 Da        Isoelectric Point: 8.7942

>AT116292 WP_010374875.1 NZ_CP034653:c4514325-4514173 [Xanthomonas vasicola pv. arecae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT116292 NZ_CP034653:c4514325-4514173 [Xanthomonas vasicola pv. arecae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGTAAGGACATGCAGGGTGCAGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A836P2V1

Antitoxin

Source ID Structure
AlphaFold DB A0A836P2N2

References