Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4527824..4528185 Replicon chromosome
Accession NZ_CP034649
Organism Xanthomonas vasicola strain NCPPB 1060

Toxin (Protein)


Gene name EcnB Uniprot ID A0A836P2V1
Locus tag NX81_RS21115 Protein ID WP_010374872.1
Coordinates 4527824..4527958 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A836P2N2
Locus tag NX81_RS21120 Protein ID WP_010374875.1
Coordinates 4528033..4528185 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NX81_RS21100 4524850..4525884 - 1035 WP_172645781.1 MBL fold metallo-hydrolase -
NX81_RS21105 4525924..4527213 - 1290 WP_010379241.1 tryptophan--tRNA ligase -
NX81_RS21110 4527382..4527594 - 213 WP_039431647.1 CsbD family protein -
NX81_RS21115 4527824..4527958 - 135 WP_010374872.1 entericidin A/B family lipoprotein Toxin
NX81_RS21120 4528033..4528185 - 153 WP_010374875.1 entericidin A/B family lipoprotein Antitoxin
NX81_RS21125 4528293..4529216 - 924 WP_039431650.1 arginase -
NX81_RS21130 4529539..4529991 + 453 WP_010374879.1 roadblock/LC7 domain-containing protein -
NX81_RS21135 4530055..4530414 + 360 WP_010374881.1 hypothetical protein -
NX81_RS21140 4530512..4531429 + 918 WP_039431653.1 hypothetical protein -
NX81_RS21145 4531426..4531968 + 543 WP_039431655.1 GTPase -
NX81_RS21155 4532447..4533130 + 684 WP_010374890.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4475.37 Da        Isoelectric Point: 10.2040

>T116288 WP_010374872.1 NZ_CP034649:c4527958-4527824 [Xanthomonas vasicola]
MKRAIVLLVLSMLSVGMLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T116288 NZ_CP034649:c4527958-4527824 [Xanthomonas vasicola]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTTTCGATGTTGTCGGTCGGTATGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5065.02 Da        Isoelectric Point: 8.7942

>AT116288 WP_010374875.1 NZ_CP034649:c4528185-4528033 [Xanthomonas vasicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT116288 NZ_CP034649:c4528185-4528033 [Xanthomonas vasicola]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGTAAGGACATGCAGGGTGCAGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A836P2V1

Antitoxin

Source ID Structure
AlphaFold DB A0A836P2N2

References