Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1820428..1820699 Replicon chromosome
Accession NZ_CP034595
Organism Escherichia coli strain WCHEC035053S1G0

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1820558..1820661 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1820428..1820699 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DK245_RS08840 1816983..1817645 - 663 WP_000944256.1 exodeoxyribonuclease X -
DK245_RS08845 1817669..1818325 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
DK245_RS08850 1818427..1818657 - 231 WP_000916763.1 DNA polymerase III subunit theta -
DK245_RS08855 1818796..1819170 + 375 WP_000168747.1 CopC domain-containing protein YobA -
DK245_RS08860 1819174..1820046 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
DK245_RS08865 1820059..1820400 + 342 WP_000976476.1 YebY family protein -
- 1820428..1820699 - 272 - - Antitoxin
- 1820558..1820661 + 104 - - Toxin
DK245_RS08870 1820796..1821452 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
DK245_RS08875 1821453..1821644 - 192 WP_000457842.1 YebW family protein -
DK245_RS08880 1821749..1821985 - 237 WP_001295499.1 DUF1480 family protein -
DK245_RS08885 1822103..1823542 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T116267 NZ_CP034595:1820558-1820661 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT116267 NZ_CP034595:c1820699-1820428 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References