Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2684514..2684785 Replicon chromosome
Accession NZ_CP034589
Organism Escherichia coli strain L37

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2684552..2684655 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2684514..2684785 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EKM58_RS13010 2681671..2683110 + 1440 WP_063091473.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
EKM58_RS13015 2683228..2683464 + 237 WP_001338166.1 DUF1480 family protein -
EKM58_RS13020 2683569..2683760 + 192 WP_001338167.1 YebW family protein -
EKM58_RS13025 2683761..2684417 - 657 WP_000812732.1 protein-serine/threonine phosphatase -
- 2684514..2684785 + 272 - - Antitoxin
- 2684552..2684655 - 104 - - Toxin
EKM58_RS13030 2684813..2685154 - 342 WP_000976472.1 YebY family protein -
EKM58_RS13035 2685167..2686039 - 873 WP_000879295.1 copper homeostasis membrane protein CopD -
EKM58_RS13040 2686043..2686417 - 375 WP_000168747.1 CopC domain-containing protein YobA -
EKM58_RS13045 2686556..2686786 + 231 WP_000916763.1 DNA polymerase III subunit theta -
EKM58_RS13050 2686888..2687544 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
EKM58_RS13055 2687568..2688230 + 663 WP_000944258.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T116237 NZ_CP034589:c2684655-2684552 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT116237 NZ_CP034589:2684514-2684785 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References