Detailed information of TA system TA116206

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yoeB-relE/YoeB-RelB
• Location: 432223..432731
• Replicon: chromosome
• Accession: NZ_CP034549
• Organism: Nonlabens ponticola strain MJ115

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: EJ995_RS01800
• Protein ID: WP_126445028.1
• Coordinates: 432223..432483 (-)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: EJ995_RS01805
• Protein ID: WP_126445030.1
• Coordinates: 432480..432731 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EJ995_RS01790	429850..430725	+	876	WP_126445024.1	pirin family protein	-
EJ995_RS01795	430726..431352	-	627	WP_164549859.1	outer membrane beta-barrel protein	-
EJ995_RS13195	431820..432233	-	414	WP_206482258.1	hypothetical protein	-
EJ995_RS01800	432223..432483	-	261	WP_126445028.1	Txe/YoeB family addiction module toxin	Toxin
EJ995_RS01805	432480..432731	-	252	WP_126445030.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
EJ995_RS01810	432770..434857	-	2088	WP_126445032.1	methionine--tRNA ligase	-
EJ995_RS01815	435130..435726	+	597	WP_126445034.1	hypothetical protein	-
EJ995_RS01820	435727..436257	-	531	WP_126445036.1	DUF4442 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-71)

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 10347.92 Da
• Isoelectric Point: 10.0816

>T116206 WP_126445028.1 NZ_CP034549:c432483-432223 [Nonlabens ponticola]
MKLTWSSQAWNDYLYWQKTDKKILKRINELIKNCSRTPFEGIGKPEALKGDLQGYWSRRITAEHRLVYKYSQDQLFIAAC
RYHYGK

Nucleotide

• Length: 261 bp

>T116206 NZ_CP034549:c432483-432223 [Nonlabens ponticola]
ATGAAACTTACCTGGTCTAGTCAAGCGTGGAATGATTACCTATATTGGCAGAAAACGGATAAGAAGATTCTGAAGAGAAT
CAACGAGCTCATCAAAAATTGCAGCCGTACACCATTTGAAGGGATAGGAAAACCCGAAGCGTTGAAAGGCGACCTGCAAG
GTTACTGGTCTAGACGTATTACCGCAGAGCATCGTCTGGTTTACAAATATTCTCAGGATCAATTATTTATCGCAGCTTGC
AGGTATCATTATGGGAAATGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9516.84 Da
• Isoelectric Point: 4.6182

>AT116206 WP_126445030.1 NZ_CP034549:c432731-432480 [Nonlabens ponticola]
MDVVNYSEFRSNLKFWFDKVITDVSDLVIKRKGGKDLVLISLDEYNSMKETAYLLSGKNRDVLLSSIRELESGNGIENDL
LEK

Nucleotide

• Length: 252 bp

>AT116206 NZ_CP034549:c432731-432480 [Nonlabens ponticola]
ATGGATGTAGTCAATTATTCTGAATTTAGATCAAATCTCAAATTTTGGTTTGATAAAGTAATCACTGATGTTAGCGACCT
CGTGATTAAAAGAAAAGGTGGCAAGGATCTAGTATTGATTTCGCTGGATGAGTATAATTCTATGAAAGAGACTGCTTATT
TATTAAGTGGAAAGAATAGAGATGTTTTGCTATCATCGATACGTGAACTAGAAAGCGGGAATGGTATAGAGAATGATTTG
CTTGAGAAATGA