Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2809407..2810046 Replicon chromosome
Accession NZ_CP034547
Organism Burkholderia cenocepacia strain YG-3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag D5R55_RS36470 Protein ID WP_206514376.1
Coordinates 2809630..2810046 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag D5R55_RS36465 Protein ID WP_126369667.1
Coordinates 2809407..2809643 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
D5R55_RS36450 2805786..2806166 + 381 WP_126369663.1 DUF4377 domain-containing protein -
D5R55_RS36455 2806176..2807564 - 1389 WP_126369665.1 DHA2 family efflux MFS transporter permease subunit -
D5R55_RS36460 2807729..2808919 - 1191 Protein_2468 acyltransferase -
D5R55_RS36465 2809407..2809643 + 237 WP_126369667.1 DNA-binding protein Antitoxin
D5R55_RS36470 2809630..2810046 + 417 WP_206514376.1 PIN domain-containing protein Toxin
D5R55_RS36475 2810384..2810587 + 204 WP_006483056.1 cold-shock protein -
D5R55_RS36485 2811052..2811315 + 264 WP_126369671.1 translation initiation factor IF-1 -
D5R55_RS36490 2811488..2811583 - 96 WP_126369673.1 alpha/beta hydrolase -
D5R55_RS36495 2811612..2811839 - 228 Protein_2474 SDR family oxidoreductase -
D5R55_RS36500 2811834..2812286 + 453 Protein_2475 helix-turn-helix domain-containing protein -
D5R55_RS36505 2812454..2813701 + 1248 WP_126369676.1 phosphoesterase -
D5R55_RS36510 2813698..2813946 + 249 WP_126369678.1 hypothetical protein -
D5R55_RS36515 2814233..2814481 + 249 WP_126369680.1 hypothetical protein -
D5R55_RS37920 2814502..2814777 - 276 WP_164725476.1 hypothetical protein -
D5R55_RS36520 2814710..2815009 + 300 WP_126369682.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-130)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15450.80 Da        Isoelectric Point: 6.8717

>T116205 WP_206514376.1 NZ_CP034547:2809630-2810046 [Burkholderia cenocepacia]
VFLIDTNVISEIRKGKRTNRGVRAFFRQVEADACPLYLSVVTVAELRRGVDLIRHRGDHSQASALEAWMAMILSGYAPNI
LPVDIEISQMWGHLRVPDATHELDKLIAATALINDLTVVTRNVDDFARTGVRLLNPFD

Download         Length: 417 bp

>T116205 NZ_CP034547:2809630-2810046 [Burkholderia cenocepacia]
GTGTTTTTGATTGATACGAACGTCATCAGCGAAATCAGGAAGGGCAAGCGAACCAACCGCGGCGTGCGGGCGTTCTTCAG
GCAGGTGGAAGCCGACGCGTGCCCGCTTTACCTGTCCGTCGTGACGGTGGCCGAGCTGCGGCGCGGTGTCGACCTGATCC
GTCATCGCGGCGATCACAGCCAGGCGTCGGCGCTCGAGGCCTGGATGGCGATGATCCTGTCCGGCTATGCGCCGAACATC
CTGCCGGTCGATATCGAGATCAGCCAGATGTGGGGGCATTTGCGCGTACCCGATGCGACGCACGAGCTCGACAAGCTGAT
CGCGGCCACCGCGCTGATCAACGATCTGACCGTCGTCACGCGCAACGTCGACGATTTCGCTCGCACCGGCGTCCGGTTGC
TGAATCCGTTCGACTAG

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8703.73 Da        Isoelectric Point: 5.6865

>AT116205 WP_126369667.1 NZ_CP034547:2809407-2809643 [Burkholderia cenocepacia]
MANLLVRNVDDTIVQSLREQAAAHGRSAEAEHRAILAEALGRPKRRTFAQVLTSMPEVGEDADFQRVQDSGEVRRVFD

Download         Length: 237 bp

>AT116205 NZ_CP034547:2809407-2809643 [Burkholderia cenocepacia]
ATGGCAAATCTTCTGGTGCGTAACGTGGATGACACTATCGTTCAAAGCCTGCGCGAGCAGGCTGCGGCCCATGGCAGGAG
CGCCGAGGCCGAACATCGAGCCATTCTGGCCGAAGCGCTCGGCCGGCCGAAGCGGCGGACTTTTGCGCAAGTGCTGACGA
GCATGCCGGAGGTGGGCGAAGACGCGGATTTCCAACGTGTTCAGGATTCAGGCGAGGTCAGGCGTGTTTTTGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References