Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 3666991..3667608 Replicon chromosome
Accession NZ_CP034483
Organism Rahnella aquatilis strain KM05

Toxin (Protein)


Gene name Hha Uniprot ID H8NYI7
Locus tag EJP80_RS17000 Protein ID WP_013576617.1
Coordinates 3667405..3667608 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID H8NYI6
Locus tag EJP80_RS16995 Protein ID WP_013576616.1
Coordinates 3666991..3667359 (+) Length 123 a.a.

Genomic Context

EJP80_RS16965EJP80_RS16970EJP80_RS16990EJP80_RS16995EJP80_RS17000EJP80_RS17010EJP80_RS17015EJP80_RS16975EJP80_RS16980EJP80_RS16985EJP80_RS17005
Location: 3662981..3663235 (255 bp)
Type: Others
Protein ID: WP_013576610.1
Location: 3663256..3663396 (141 bp)
Type: Others
Protein ID: WP_013576611.1
Location: 3666408..3666761 (354 bp)
Type: Others
Protein ID: WP_013576615.1
Location: 3666991..3667359 (369 bp)
Type: Antitoxin
Protein ID: WP_013576616.1
Location: 3667405..3667608 (204 bp)
Type: Toxin
Protein ID: WP_013576617.1
Location: 3668780..3670567 (1788 bp)
Type: Others
Protein ID: WP_013576619.1
Location: 3670644..3671993 (1350 bp)
Type: Others
Protein ID: WP_119261884.1
Location: 3663521..3664399 (879 bp)
Type: Others
Protein ID: WP_013576612.1
Location: 3664443..3665300 (858 bp)
Type: Others
Protein ID: WP_013576613.1
Location: 3665297..3666025 (729 bp)
Type: Others
Protein ID: WP_173362112.1
Location: 3667684..3668640 (957 bp)
Type: Others
Protein ID: WP_013576618.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EJP80_RS169653662981..3663235+255WP_013576610.1type B 50S ribosomal protein L31-
EJP80_RS169703663256..3663396+141WP_013576611.1type B 50S ribosomal protein L36-
EJP80_RS169753663521..3664399-879WP_013576612.1metal ABC transporter substrate-binding protein-
EJP80_RS169803664443..3665300-858WP_013576613.1metal ABC transporter permease-
EJP80_RS169853665297..3666025-729WP_173362112.1ABC transporter ATP-binding protein-
EJP80_RS169903666408..3666761+354WP_013576615.1hypothetical protein-
EJP80_RS169953666991..3667359+369WP_013576616.1Hha toxicity modulator TomBAntitoxin
EJP80_RS170003667405..3667608+204WP_013576617.1hemolysin expression modulator HhaToxin
EJP80_RS170053667684..3668640-957WP_013576618.1LysR family transcriptional regulator-
EJP80_RS170103668780..3670567+1788WP_013576619.1adenine deaminase-
EJP80_RS170153670644..3671993+1350WP_119261884.1NCS2 family permease-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8114.45 Da        Isoelectric Point: 6.9764

>T116163 WP_013576617.1 NZ_CP034483:3667405-3667608 [Rahnella aquatilis]
MNKIDYLMRLRKCTTIDTLERVIEKNKYELSDDELELFYSAADHRLAELTMNKLYDKIPVSVWKFVR

Download         Length: 204 bp

>T116163 NZ_CP034483:3667405-3667608 [Rahnella aquatilis]
ATGAACAAAATCGACTATTTGATGCGTTTACGAAAATGCACCACTATCGATACACTTGAACGTGTTATTGAAAAAAATAA
GTACGAACTTTCCGACGACGAGCTGGAATTGTTTTACTCGGCAGCTGACCATCGTTTAGCGGAGCTAACGATGAACAAGT
TGTACGATAAAATCCCGGTATCAGTCTGGAAATTTGTACGCTGA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14391.15 Da        Isoelectric Point: 4.7281

>AT116163 WP_013576616.1 NZ_CP034483:3666991-3667359 [Rahnella aquatilis]
MDEYSPKRHDIAQLRYLNEMLYDEGIATLGDSHHGWVNDPTSAVNLQLNELIEHIASFVMSFKIKYPDDNHLSDLVEEYL
DDTYTLFSNYGINDSDLRQWQKTKKRLFRMFSGDYICTLMKT

Download         Length: 369 bp

>AT116163 NZ_CP034483:3666991-3667359 [Rahnella aquatilis]
ATGGATGAGTACTCGCCTAAGCGGCACGATATCGCTCAGTTACGCTACCTGAATGAAATGCTGTATGATGAAGGGATTGC
GACACTGGGTGACAGTCATCATGGTTGGGTTAACGATCCGACTTCGGCTGTTAACTTGCAGCTCAATGAACTGATTGAGC
ACATTGCATCCTTTGTGATGAGTTTTAAAATTAAGTATCCAGACGATAACCATTTAAGTGATCTGGTTGAAGAGTATCTG
GATGATACCTACACGCTGTTCAGTAATTATGGAATTAACGATTCTGATTTACGCCAATGGCAAAAGACCAAGAAGCGGTT
ATTCAGAATGTTCTCAGGGGACTACATCTGTACCCTAATGAAGACTTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBH8NYI7

Antitoxin

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Source
ID
Structure
AlphaFold DBH8NYI6

References