Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 4199236..4200063 Replicon chromosome
Accession NZ_CP034481
Organism Rahnella aquatilis strain KM25

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag EJP79_RS19315 Protein ID WP_126125193.1
Coordinates 4199236..4199619 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag EJP79_RS19320 Protein ID WP_126125194.1
Coordinates 4199695..4200063 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJP79_RS19300 4195299..4196162 - 864 Protein_3768 DUF4942 domain-containing protein -
EJP79_RS19305 4196301..4197527 - 1227 WP_126125191.1 O-antigen ligase family protein -
EJP79_RS19310 4197524..4198699 - 1176 WP_126125192.1 putative lipopolysaccharide heptosyltransferase III -
EJP79_RS19315 4199236..4199619 - 384 WP_126125193.1 TA system toxin CbtA family protein Toxin
EJP79_RS19320 4199695..4200063 - 369 WP_126125194.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
EJP79_RS19325 4200119..4200325 - 207 WP_126125195.1 hypothetical protein -
EJP79_RS19330 4200335..4200784 - 450 WP_126125196.1 DNA repair protein RadC -
EJP79_RS19335 4200877..4201698 - 822 WP_126125197.1 DUF945 domain-containing protein -
EJP79_RS19340 4201815..4202933 - 1119 WP_126125198.1 hypothetical protein -
EJP79_RS19345 4203371..4204255 - 885 WP_126125199.1 50S ribosome-binding GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4182988..4249556 66568


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(13-112)

Antitoxin

Antitoxin CbeA

(18-117)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14198.12 Da        Isoelectric Point: 8.0195

>T116133 WP_126125193.1 NZ_CP034481:c4199619-4199236 [Rahnella aquatilis]
MKTSISAAPSAVPVSSCPSHVAVWQQLLTYLFDRHYGLTLNDTPFHYESVIEEYIDAGISLKDAVNFVAERYGLLRIDRS
SSAYAEQPPFISYVNILQARRATGLMPQGGYKEIRVLTQGKRTTEGR

Download         Length: 384 bp

>T116133 NZ_CP034481:c4199619-4199236 [Rahnella aquatilis]
ATGAAAACCTCAATCTCTGCGGCACCGTCAGCGGTGCCAGTATCGTCATGCCCGTCGCACGTGGCCGTTTGGCAGCAGCT
GCTGACGTATCTGTTCGACCGCCATTACGGCCTGACGCTCAACGACACGCCGTTCCACTATGAATCCGTGATAGAGGAAT
ATATCGATGCCGGTATTTCTTTGAAAGACGCGGTGAACTTTGTGGCCGAACGATATGGCCTTCTGCGCATTGACCGCAGC
AGCAGTGCTTACGCTGAACAGCCGCCGTTCATTTCCTACGTCAACATTCTTCAGGCGCGTCGGGCCACTGGCCTGATGCC
ACAAGGAGGATATAAAGAGATAAGGGTTCTCACCCAGGGGAAAAGGACCACCGAAGGCAGGTGA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13351.20 Da        Isoelectric Point: 6.0553

>AT116133 WP_126125194.1 NZ_CP034481:c4200063-4199695 [Rahnella aquatilis]
MTLPLPPATQPTVVPAGPQWGLIRDISPCFGARLVQEGNRLHYLADRAGFCGEFTADDALRLDQAFPLILKQLEQTLLSG
GLDPRRQQRVTLHHNGLTCDADTLGSHGYVYLSIYPTPPEAT

Download         Length: 369 bp

>AT116133 NZ_CP034481:c4200063-4199695 [Rahnella aquatilis]
ATGACTCTCCCACTCCCCCCGGCCACCCAGCCGACAGTCGTCCCTGCGGGTCCGCAATGGGGGCTGATCCGCGATATATC
TCCGTGCTTCGGTGCCCGCCTGGTGCAGGAAGGCAACCGTCTGCATTATCTGGCCGACCGGGCAGGCTTCTGTGGTGAAT
TTACTGCCGACGACGCCCTGCGGCTCGATCAGGCATTTCCACTAATACTGAAACAATTGGAGCAGACGCTGTTGTCCGGT
GGGCTTGATCCGCGCCGCCAGCAACGCGTTACACTCCATCACAACGGCCTGACCTGCGACGCTGACACCCTCGGGTCGCA
CGGCTATGTGTACCTGTCCATTTATCCAACACCACCTGAGGCAACATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References