Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hipBA/HipA-HipB |
Location | 1998018..1999579 | Replicon | chromosome |
Accession | NZ_CP034469 | ||
Organism | Pantoea agglomerans strain CFSAN047153 |
Toxin (Protein)
Gene name | hipA | Uniprot ID | - |
Locus tag | D1628_RS09385 | Protein ID | WP_129062929.1 |
Coordinates | 1998018..1999331 (-) | Length | 438 a.a. |
Antitoxin (Protein)
Gene name | hipB | Uniprot ID | - |
Locus tag | D1628_RS09390 | Protein ID | WP_061703948.1 |
Coordinates | 1999331..1999579 (-) | Length | 83 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
D1628_RS09365 | 1993425..1993760 | + | 336 | WP_129062927.1 | gamma-glutamylcyclotransferase | - |
D1628_RS09370 | 1993993..1996038 | - | 2046 | WP_010244891.1 | FUSC family protein | - |
D1628_RS09375 | 1996114..1997535 | - | 1422 | WP_129062928.1 | M24 family metallopeptidase | - |
D1628_RS09380 | 1997707..1997913 | - | 207 | WP_010244885.1 | type II toxin-antitoxin system MqsA family antitoxin | - |
D1628_RS09385 | 1998018..1999331 | - | 1314 | WP_129062929.1 | type II toxin-antitoxin system HipA family toxin | Toxin |
D1628_RS09390 | 1999331..1999579 | - | 249 | WP_061703948.1 | type II toxin-antitoxin system antitoxin HipB | Antitoxin |
D1628_RS09395 | 1999760..2000197 | + | 438 | WP_061703947.1 | GNAT family N-acetyltransferase | - |
D1628_RS09400 | 2000231..2001025 | - | 795 | WP_061703946.1 | inositol monophosphatase family protein | - |
D1628_RS09405 | 2001049..2002110 | - | 1062 | WP_061703945.1 | ABC transporter ATP-binding protein | - |
D1628_RS09410 | 2002107..2004332 | - | 2226 | WP_061703944.1 | iron ABC transporter permease | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 438 a.a. Molecular weight: 49113.72 Da Isoelectric Point: 7.8460
>T116098 WP_129062929.1 NZ_CP034469:c1999331-1998018 [Pantoea agglomerans]
MQRLIAWMNGERVGVLTRQRNGAHEFQYDTGWLSNPLSRPLSLSMPLQVKALTSHAVINFFDNLLPDSPLIRDRIVARYQ
IKSCQPFDLLQEVGRDSVGATMLLPPDMPLPALQARYEVLDETRLESVLSAYQSDIPLGMLREETDFRISVAGAQEKTAL
LLTDEGWSIPAGATPTSHIIKLPIGEIKQPAATLDMRESVENEYLCLALARALGIDVPQATIIRAGQMRALAVERFDRRW
SRDKTRLIRLPQEDFCQALGLPSSTKYESDGGPGIVEIMQILMGSSNAIEDRYRFMMFQVFQWLIGATDGHAKNFSLFIE
RGGSYRLTPFYDVISAYPVLGGTGLNKRALKLAMGLRATKGKKTEIDKIFPRHFIATAKSVSFDRDSLQQIFDFFIKAFP
QAVVSVRDALPPDFPQHIADAIFSHSLIMLERLRQKE
MQRLIAWMNGERVGVLTRQRNGAHEFQYDTGWLSNPLSRPLSLSMPLQVKALTSHAVINFFDNLLPDSPLIRDRIVARYQ
IKSCQPFDLLQEVGRDSVGATMLLPPDMPLPALQARYEVLDETRLESVLSAYQSDIPLGMLREETDFRISVAGAQEKTAL
LLTDEGWSIPAGATPTSHIIKLPIGEIKQPAATLDMRESVENEYLCLALARALGIDVPQATIIRAGQMRALAVERFDRRW
SRDKTRLIRLPQEDFCQALGLPSSTKYESDGGPGIVEIMQILMGSSNAIEDRYRFMMFQVFQWLIGATDGHAKNFSLFIE
RGGSYRLTPFYDVISAYPVLGGTGLNKRALKLAMGLRATKGKKTEIDKIFPRHFIATAKSVSFDRDSLQQIFDFFIKAFP
QAVVSVRDALPPDFPQHIADAIFSHSLIMLERLRQKE
Download Length: 1314 bp
>T116098 NZ_CP034469:c1999331-1998018 [Pantoea agglomerans]
ATGCAAAGGCTGATTGCGTGGATGAACGGCGAGCGGGTAGGCGTACTCACCCGGCAGCGAAACGGCGCTCATGAGTTTCA
GTATGATACCGGCTGGCTGAGTAATCCGCTCTCCAGGCCGCTGTCACTTTCGATGCCGTTGCAGGTTAAGGCTCTCACCT
CACACGCCGTGATTAACTTCTTCGATAATCTGCTGCCGGATAGCCCATTGATTCGCGACAGAATCGTGGCGCGTTACCAG
ATTAAATCCTGTCAGCCGTTTGATCTGTTGCAGGAAGTGGGACGTGACAGCGTCGGGGCGACTATGCTGCTGCCGCCCGA
TATGCCACTGCCCGCACTGCAGGCCCGCTATGAAGTGCTGGATGAAACCCGGCTCGAAAGCGTGCTGTCGGCCTATCAGT
CAGATATCCCGCTGGGGATGCTGCGTGAAGAGACCGATTTCCGTATCTCGGTCGCGGGGGCGCAGGAGAAAACCGCACTG
CTGCTGACCGATGAAGGCTGGAGCATTCCTGCCGGTGCCACGCCCACCTCGCACATCATTAAGCTGCCGATCGGAGAGAT
TAAACAGCCGGCCGCGACGCTGGATATGCGTGAAAGTGTGGAGAATGAGTATCTCTGTCTGGCGCTGGCCCGTGCACTCG
GTATCGACGTGCCGCAGGCAACGATTATTCGTGCCGGACAGATGCGCGCCCTGGCGGTAGAACGTTTCGACCGCCGCTGG
TCACGCGATAAAACCCGGTTGATTCGCCTGCCGCAGGAGGATTTCTGTCAGGCGCTGGGACTGCCATCTTCAACCAAATA
TGAGTCGGATGGCGGGCCGGGCATTGTGGAGATCATGCAGATACTGATGGGATCGAGCAACGCCATCGAAGATCGCTATC
GCTTTATGATGTTCCAGGTGTTTCAGTGGCTGATTGGCGCAACTGACGGTCACGCCAAGAACTTCTCACTGTTTATTGAG
CGCGGTGGCAGTTATCGACTGACTCCCTTTTATGATGTGATCTCCGCTTACCCGGTACTGGGCGGCACCGGTCTGAACAA
GCGAGCGCTGAAACTGGCGATGGGTCTGCGTGCCACTAAGGGGAAGAAGACAGAAATCGATAAAATCTTCCCGCGCCATT
TTATCGCCACGGCAAAAAGCGTCAGTTTTGATCGTGACAGTTTGCAGCAGATCTTCGACTTCTTTATTAAGGCCTTTCCC
CAGGCAGTGGTCTCGGTGCGCGATGCTTTGCCGCCCGATTTCCCGCAGCACATCGCCGACGCCATCTTCAGTCATTCACT
CATTATGCTGGAGCGGCTACGGCAAAAAGAGTGA
ATGCAAAGGCTGATTGCGTGGATGAACGGCGAGCGGGTAGGCGTACTCACCCGGCAGCGAAACGGCGCTCATGAGTTTCA
GTATGATACCGGCTGGCTGAGTAATCCGCTCTCCAGGCCGCTGTCACTTTCGATGCCGTTGCAGGTTAAGGCTCTCACCT
CACACGCCGTGATTAACTTCTTCGATAATCTGCTGCCGGATAGCCCATTGATTCGCGACAGAATCGTGGCGCGTTACCAG
ATTAAATCCTGTCAGCCGTTTGATCTGTTGCAGGAAGTGGGACGTGACAGCGTCGGGGCGACTATGCTGCTGCCGCCCGA
TATGCCACTGCCCGCACTGCAGGCCCGCTATGAAGTGCTGGATGAAACCCGGCTCGAAAGCGTGCTGTCGGCCTATCAGT
CAGATATCCCGCTGGGGATGCTGCGTGAAGAGACCGATTTCCGTATCTCGGTCGCGGGGGCGCAGGAGAAAACCGCACTG
CTGCTGACCGATGAAGGCTGGAGCATTCCTGCCGGTGCCACGCCCACCTCGCACATCATTAAGCTGCCGATCGGAGAGAT
TAAACAGCCGGCCGCGACGCTGGATATGCGTGAAAGTGTGGAGAATGAGTATCTCTGTCTGGCGCTGGCCCGTGCACTCG
GTATCGACGTGCCGCAGGCAACGATTATTCGTGCCGGACAGATGCGCGCCCTGGCGGTAGAACGTTTCGACCGCCGCTGG
TCACGCGATAAAACCCGGTTGATTCGCCTGCCGCAGGAGGATTTCTGTCAGGCGCTGGGACTGCCATCTTCAACCAAATA
TGAGTCGGATGGCGGGCCGGGCATTGTGGAGATCATGCAGATACTGATGGGATCGAGCAACGCCATCGAAGATCGCTATC
GCTTTATGATGTTCCAGGTGTTTCAGTGGCTGATTGGCGCAACTGACGGTCACGCCAAGAACTTCTCACTGTTTATTGAG
CGCGGTGGCAGTTATCGACTGACTCCCTTTTATGATGTGATCTCCGCTTACCCGGTACTGGGCGGCACCGGTCTGAACAA
GCGAGCGCTGAAACTGGCGATGGGTCTGCGTGCCACTAAGGGGAAGAAGACAGAAATCGATAAAATCTTCCCGCGCCATT
TTATCGCCACGGCAAAAAGCGTCAGTTTTGATCGTGACAGTTTGCAGCAGATCTTCGACTTCTTTATTAAGGCCTTTCCC
CAGGCAGTGGTCTCGGTGCGCGATGCTTTGCCGCCCGATTTCCCGCAGCACATCGCCGACGCCATCTTCAGTCATTCACT
CATTATGCTGGAGCGGCTACGGCAAAAAGAGTGA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9342.59 Da Isoelectric Point: 5.5976
>AT116098 WP_061703948.1 NZ_CP034469:c1999579-1999331 [Pantoea agglomerans]
MIYSPLQLANRLKLIRQRNGWTQSELAKKVGLKQATISHFENAPDSTSLATLFKLLQSLELSLEVHEKEEAGAPQLHDED
EW
MIYSPLQLANRLKLIRQRNGWTQSELAKKVGLKQATISHFENAPDSTSLATLFKLLQSLELSLEVHEKEEAGAPQLHDED
EW
Download Length: 249 bp
>AT116098 NZ_CP034469:c1999579-1999331 [Pantoea agglomerans]
ATGATATACAGCCCGCTACAGCTGGCAAACCGGCTAAAGCTCATTCGTCAGCGCAATGGCTGGACCCAGAGTGAGCTGGC
GAAAAAGGTCGGCCTGAAACAGGCCACCATCTCTCACTTTGAAAATGCCCCTGACAGTACCTCGCTGGCAACGCTGTTTA
AGCTGTTACAGTCGCTTGAGCTGAGTCTGGAAGTTCACGAGAAAGAGGAGGCCGGTGCGCCTCAGCTGCATGATGAGGAT
GAGTGGTAA
ATGATATACAGCCCGCTACAGCTGGCAAACCGGCTAAAGCTCATTCGTCAGCGCAATGGCTGGACCCAGAGTGAGCTGGC
GAAAAAGGTCGGCCTGAAACAGGCCACCATCTCTCACTTTGAAAATGCCCCTGACAGTACCTCGCTGGCAACGCTGTTTA
AGCTGTTACAGTCGCTTGAGCTGAGTCTGGAAGTTCACGAGAAAGAGGAGGCCGGTGCGCCTCAGCTGCATGATGAGGAT
GAGTGGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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