Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Fic(toxin)
Location 4351303..4351868 Replicon chromosome
Accession NZ_CP034463
Organism Streptomyces aquilus strain GGCR-6

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag EJC51_RS20015 Protein ID WP_126272351.1
Coordinates 4351303..4351671 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag EJC51_RS20020 Protein ID WP_123761049.1
Coordinates 4351671..4351868 (-) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJC51_RS19990 4346788..4347372 + 585 WP_126272347.1 transcriptional regulator -
EJC51_RS19995 4347372..4347554 + 183 WP_126277050.1 hypothetical protein -
EJC51_RS20000 4347551..4348342 - 792 WP_126272348.1 hypothetical protein -
EJC51_RS20005 4348418..4349059 - 642 WP_126272349.1 helix-turn-helix domain-containing protein -
EJC51_RS20010 4349392..4351191 - 1800 WP_126272350.1 DEAD/DEAH box helicase -
EJC51_RS20015 4351303..4351671 - 369 WP_126272351.1 Fic family protein Toxin
EJC51_RS20020 4351671..4351868 - 198 WP_123761049.1 hypothetical protein Antitoxin
EJC51_RS20025 4351901..4353364 - 1464 WP_126272352.1 MFS transporter -
EJC51_RS20035 4353722..4354105 - 384 WP_126272353.1 hypothetical protein -
EJC51_RS20040 4354310..4355488 - 1179 WP_126272354.1 SUKH-4 family immunity protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Fido domain

(18-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13655.53 Da        Isoelectric Point: 5.5038

>T116092 WP_126272351.1 NZ_CP034463:c4351671-4351303 [Streptomyces aquilus]
MHYLTLPELLNLAMRLGADEVRDYGLLDSASARPQSSVFGQDAYPDVWQKAAALMESLARNHALVDGNKRIAWYATWVFL
HMNGHPLDAGFDVDEAERFVFDVCQGALDVPKIAAHLPRFAR

Download         Length: 369 bp

>T116092 NZ_CP034463:c4351671-4351303 [Streptomyces aquilus]
ATGCACTACCTCACGTTGCCCGAGCTGCTGAACCTGGCGATGCGGCTCGGGGCAGATGAGGTGCGTGACTACGGGCTGCT
GGACTCGGCCTCGGCCCGTCCGCAGTCCAGCGTGTTCGGGCAGGACGCCTATCCGGACGTATGGCAGAAGGCTGCCGCAC
TGATGGAGTCGCTGGCCCGCAACCACGCGCTCGTCGACGGGAACAAGCGCATCGCCTGGTACGCGACCTGGGTTTTCCTG
CACATGAACGGGCACCCCTTGGACGCCGGCTTCGACGTGGACGAGGCCGAGCGCTTCGTTTTCGACGTCTGTCAGGGCGC
CCTGGACGTGCCCAAGATCGCGGCCCATCTGCCGCGCTTCGCGCGCTGA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7176.03 Da        Isoelectric Point: 5.5676

>AT116092 WP_123761049.1 NZ_CP034463:c4351868-4351671 [Streptomyces aquilus]
MAGLNLRFTDEELDALRERAAAEGRSMQAFAHDAVIAAINEHSRLFNEAADHVLKASAELNRRLA

Download         Length: 198 bp

>AT116092 NZ_CP034463:c4351868-4351671 [Streptomyces aquilus]
ATGGCTGGACTGAATCTGCGTTTCACGGACGAAGAGCTTGATGCCCTGCGTGAGCGTGCGGCGGCGGAAGGACGCAGCAT
GCAGGCGTTCGCGCACGACGCGGTGATCGCGGCCATAAACGAGCACTCACGTCTGTTCAACGAGGCGGCGGATCACGTCC
TGAAGGCGAGCGCCGAGCTGAACCGGAGGCTCGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References