Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PrpT-parD/ParE-RHH
Location 5161251..5161777 Replicon chromosome
Accession NZ_CP034451
Organism Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1

Toxin (Protein)


Gene name PrpT Uniprot ID -
Locus tag EJ074_RS24640 Protein ID WP_095806876.1
Coordinates 5161251..5161544 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag EJ074_RS24645 Protein ID WP_095806875.1
Coordinates 5161541..5161777 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJ074_RS24615 5156627..5157580 + 954 WP_095806881.1 LysR family transcriptional regulator -
EJ074_RS24620 5157586..5158536 - 951 WP_095806880.1 trypsin-like peptidase domain-containing protein -
EJ074_RS24625 5158747..5159622 + 876 WP_095806879.1 S1C family serine protease -
EJ074_RS24630 5159630..5160277 + 648 WP_095806878.1 LuxR family transcriptional regulator -
EJ074_RS24635 5160388..5161254 + 867 WP_095806877.1 NAD(P)-dependent oxidoreductase -
EJ074_RS24640 5161251..5161544 - 294 WP_095806876.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EJ074_RS24645 5161541..5161777 - 237 WP_095806875.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
EJ074_RS24650 5162267..5164453 - 2187 WP_095806874.1 OmpA family protein -
EJ074_RS24655 5164649..5165095 + 447 WP_095807031.1 YcgN family cysteine cluster protein -
EJ074_RS24660 5165551..5165898 + 348 WP_095806873.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-93)

Antitoxin

Antitoxin ParD

(1-77)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11314.05 Da        Isoelectric Point: 10.3352

>T116091 WP_095806876.1 NZ_CP034451:c5161544-5161251 [Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1]
MKRTVRISPRAKRDLDGIWDYSLNQWGAERAEAYIRSIHSVVTLMDQFPAIARNASDVRPGLLKYAVGSHVVYLRMNHQS
IDIVRILHQQMDYPRHL

Download         Length: 294 bp

>T116091 NZ_CP034451:c5161544-5161251 [Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1]
ATGAAAAGAACGGTCCGGATTTCGCCGCGAGCGAAGCGGGACCTCGATGGTATCTGGGATTATTCGCTGAATCAGTGGGG
CGCTGAGCGGGCAGAAGCCTACATCCGCTCAATCCACTCCGTGGTCACGTTGATGGACCAGTTTCCAGCAATAGCGCGGA
ATGCCTCGGACGTCAGGCCTGGCCTGCTCAAATATGCTGTCGGTTCTCACGTGGTGTATCTGCGAATGAATCACCAATCC
ATCGATATTGTGCGCATTTTGCATCAACAGATGGACTACCCCAGGCACCTTTAG

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8746.87 Da        Isoelectric Point: 5.1231

>AT116091 WP_095806875.1 NZ_CP034451:c5161777-5161541 [Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1]
MSKNTSVTLGDQYDAFIQRQIAKGRFGSASETVRAGLRLLEEQELKLEQLRAAIDEGDMSGSLEPFDIEAFLNAKKRR

Download         Length: 237 bp

>AT116091 NZ_CP034451:c5161777-5161541 [Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1]
ATGTCCAAAAACACCTCCGTGACCCTTGGCGATCAGTACGACGCATTTATCCAGCGGCAGATAGCAAAGGGCCGCTTCGG
CTCGGCGAGTGAAACAGTCCGCGCAGGTCTTCGCCTCCTCGAAGAACAGGAATTGAAGCTCGAGCAGCTTCGTGCCGCTA
TCGACGAAGGAGACATGTCGGGCAGCCTCGAGCCATTCGACATTGAGGCGTTTCTCAATGCGAAGAAGCGCCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References