Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 3167098..3167783 Replicon chromosome
Accession NZ_CP034451
Organism Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EJ074_RS15050 Protein ID WP_095805114.1
Coordinates 3167098..3167520 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EJ074_RS15055 Protein ID WP_095805115.1
Coordinates 3167517..3167783 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJ074_RS15030 3162583..3163692 + 1110 WP_095805110.1 Gfo/Idh/MocA family oxidoreductase -
EJ074_RS15035 3163705..3164406 - 702 WP_095805111.1 YafY family transcriptional regulator -
EJ074_RS15040 3164534..3165169 + 636 WP_095805112.1 LysE family translocator -
EJ074_RS15045 3165197..3166288 - 1092 WP_095805433.1 3-deoxy-7-phosphoheptulonate synthase -
EJ074_RS15050 3167098..3167520 - 423 WP_095805114.1 type II toxin-antitoxin system VapC family toxin Toxin
EJ074_RS15055 3167517..3167783 - 267 WP_095805115.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EJ074_RS15060 3167944..3168738 - 795 WP_095805116.1 SDR family oxidoreductase -
EJ074_RS15065 3168768..3169760 - 993 WP_095805117.1 inositol 2-dehydrogenase -
EJ074_RS15070 3169841..3170611 - 771 WP_040972873.1 sugar ABC transporter ATP-binding protein -
EJ074_RS15075 3170614..3171690 - 1077 WP_095805118.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-125)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-72)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15605.84 Da        Isoelectric Point: 4.5606

>T116090 WP_095805114.1 NZ_CP034451:c3167520-3167098 [Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1]
VRILLDTNVLSEVTRPAPDTRVLGWLDELDEDRSFISVVSIAEIRRGVALMDDGRKREALAEWLARDLPQRFEQRVLPVD
EAVALAWGDLMGLAKRRGRGLSSMDGLIAATAIAQQLTLATRNTKDFEGFGIEIFDPWTA

Download         Length: 423 bp

>T116090 NZ_CP034451:c3167520-3167098 [Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1]
GTGAGGATACTGCTTGATACGAATGTCCTGTCCGAAGTGACGAGGCCGGCTCCAGACACACGCGTGTTGGGTTGGCTGGA
CGAGCTTGACGAGGACCGCTCGTTCATCAGCGTTGTGTCGATCGCCGAGATCCGGCGCGGCGTTGCCCTCATGGATGACG
GCCGCAAACGCGAGGCACTGGCTGAATGGCTCGCTCGGGACTTGCCGCAGCGCTTCGAGCAGAGGGTTTTGCCGGTGGAT
GAAGCGGTTGCGTTGGCCTGGGGCGACCTAATGGGGCTTGCCAAGCGCCGCGGTCGCGGTCTGTCGTCGATGGACGGCCT
GATCGCGGCCACCGCGATTGCGCAGCAGCTCACCTTGGCAACGCGCAACACAAAGGATTTCGAAGGCTTTGGAATCGAAA
TTTTCGATCCCTGGACTGCATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9823.17 Da        Isoelectric Point: 10.1732

>AT116090 WP_095805115.1 NZ_CP034451:c3167783-3167517 [Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1]
MLPGPKEDVSWTVAGAKARLSEVIDRAQSSPQTITRNGKPSVVVVSVDEWRRKTARKGTLAEFLLESPLRGSDLNLERQR
DEPRDLPL

Download         Length: 267 bp

>AT116090 NZ_CP034451:c3167783-3167517 [Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1]
ATGCTGCCTGGACCCAAAGAAGATGTGAGCTGGACGGTCGCTGGGGCAAAAGCCCGGCTCTCGGAGGTTATAGATCGGGC
ACAATCGTCGCCGCAGACGATCACCCGAAACGGCAAACCAAGCGTCGTCGTCGTGTCGGTAGACGAATGGCGGCGCAAGA
CCGCACGGAAAGGCACCCTCGCTGAGTTCCTGCTGGAGTCGCCGTTGCGCGGCTCCGATTTGAACCTTGAGCGTCAACGC
GACGAGCCGCGTGACCTGCCGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References