Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 1524541..1525006 Replicon chromosome
Accession NZ_CP034451
Organism Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag EJ074_RS07540 Protein ID WP_095808683.1
Coordinates 1524541..1524801 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag EJ074_RS07545 Protein ID WP_095808682.1
Coordinates 1524785..1525006 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJ074_RS07520 1520493..1521743 - 1251 WP_129552875.1 endolytic transglycosylase MltG -
EJ074_RS07525 1521829..1523091 - 1263 WP_095808685.1 beta-ketoacyl-ACP synthase II -
EJ074_RS07530 1523126..1523362 - 237 WP_006203723.1 acyl carrier protein -
EJ074_RS07535 1523764..1524501 - 738 WP_129552876.1 3-oxoacyl-[acyl-carrier-protein] reductase -
EJ074_RS07540 1524541..1524801 - 261 WP_095808683.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
EJ074_RS07545 1524785..1525006 - 222 WP_095808682.1 ribbon-helix-helix protein, CopG family Antitoxin
EJ074_RS07550 1525079..1526020 - 942 WP_095808681.1 ACP S-malonyltransferase -
EJ074_RS07555 1526296..1528224 + 1929 WP_095808680.1 LTA synthase family protein -
EJ074_RS07560 1528538..1529029 + 492 WP_095808679.1 30S ribosomal protein S6 -
EJ074_RS07565 1529029..1529277 + 249 WP_006203718.1 30S ribosomal protein S18 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-85)

Antitoxin

Ribbon-helix-helix protein, CopG

(3-39)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10113.68 Da        Isoelectric Point: 10.3399

>T116089 WP_095808683.1 NZ_CP034451:c1524801-1524541 [Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1]
VAWTLEYARSARKFVEKLDPHTRNHIRDFVENRLVVLDNPRDLGKPLKGPLATFWRYRVGDYRVICDVQDSRLVILVVTI
GHRGER

Download         Length: 261 bp

>T116089 NZ_CP034451:c1524801-1524541 [Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1]
GTGGCTTGGACGCTTGAGTACGCTCGCTCAGCCCGCAAATTTGTCGAAAAACTGGATCCGCACACGCGCAATCATATCCG
CGACTTCGTCGAAAACCGCCTTGTCGTGCTCGACAATCCGCGTGATCTCGGCAAGCCGCTGAAAGGGCCGTTAGCGACAT
TCTGGAGATACCGAGTTGGCGACTATCGCGTTATTTGCGATGTGCAGGACAGCCGGTTGGTTATCCTCGTCGTCACGATA
GGTCATCGAGGCGAGAGATAG

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8531.59 Da        Isoelectric Point: 4.3438

>AT116089 WP_095808682.1 NZ_CP034451:c1525006-1524785 [Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1]
VPTSIRLAPDIEERLDFLAAKTGRSKAYYLRELIERGLEDVEDYYLAAEVLERIRRGEEDVLKSEDFWRGLDA

Download         Length: 222 bp

>AT116089 NZ_CP034451:c1525006-1524785 [Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1]
GTGCCAACTTCGATCCGCCTGGCCCCTGACATCGAGGAGCGCCTGGACTTTCTTGCTGCCAAGACTGGACGGAGCAAGGC
TTACTACCTACGAGAACTCATCGAGCGTGGGCTCGAGGACGTGGAGGATTACTATCTTGCCGCCGAGGTACTCGAGCGGA
TCAGGCGTGGCGAGGAAGACGTCTTGAAGAGCGAGGATTTCTGGCGTGGCTTGGACGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References