Detailed information of TA system TA116088

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/DUF1778(antitoxin)
• Location: 111976..112778
• Replicon: chromosome
• Accession: NZ_CP034451
• Organism: Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1

Toxin (Protein)

• Gene name: TacT3
• Uniprot ID: -
• Locus tag: EJ074_RS00500
• Protein ID: WP_127228077.1
• Coordinates: 111976..112503 (-)
• Length: 176 a.a.

Antitoxin (Protein)

• Gene name: TacA3
• Uniprot ID: -
• Locus tag: EJ074_RS00505
• Protein ID: WP_129552540.1
• Coordinates: 112500..112778 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EJ074_RS00460	107091..107327	-	237	WP_129552532.1	multiubiquitin domain-containing protein	-
EJ074_RS00465	107318..107857	-	540	WP_129552533.1	hypothetical protein	-
EJ074_RS00470	107854..109182	-	1329	WP_129552534.1	ThiF family adenylyltransferase	-
EJ074_RS00475	109179..109574	-	396	WP_129552535.1	hypothetical protein	-
EJ074_RS00480	109571..109831	-	261	WP_129552536.1	hypothetical protein	-
EJ074_RS00485	110100..110771	-	672	WP_129552537.1	SMC-Scp complex subunit ScpB	-
EJ074_RS00490	110774..111730	-	957	WP_129552538.1	DUF1403 family protein	-
EJ074_RS00495	111768..111965	-	198	WP_129552539.1	hypothetical protein	-
EJ074_RS00500	111976..112503	-	528	WP_127228077.1	GNAT family N-acetyltransferase	Toxin
EJ074_RS00505	112500..112778	-	279	WP_129552540.1	DUF1778 domain-containing protein	Antitoxin
EJ074_RS00510	112853..113992	+	1140	WP_129552541.1	site-specific integrase	-
EJ074_RS00515	114010..114354	-	345	WP_129552542.1	helix-turn-helix domain-containing protein	-
EJ074_RS00520	114560..115888	-	1329	WP_129552543.1	replication initiation protein RepC	-
EJ074_RS00525	116049..117044	-	996	WP_129552544.1	plasmid partitioning protein RepB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Vibrio phage ICP1, Orf50 (11-87)

Sequences

Toxin

Protein

• Length: 176 a.a.
• Molecular weight: 18880.74 Da
• Isoelectric Point: 7.4447

>T116088 WP_127228077.1 NZ_CP034451:c112503-111976 [Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1]
VSLPPWHEEAIARSHDRKAFDCGDVEMNAFLQRFARQGHEQNAVKSFCAVPDDAPEKILGFYSLAPASVEHHAVPPPMTK
GLARHDVPGFLLARLAVDKSVAGRGLGGQLLLAAALRCIRVTEEVGGVLMIIDAKSSRAASWYASYGAEPLNDRPMTLVV
PLKTFAETLKASGHL

Nucleotide

• Length: 528 bp

>T116088 NZ_CP034451:c112503-111976 [Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1]
GTGAGCCTTCCGCCCTGGCATGAGGAGGCGATCGCCCGGTCGCACGACCGGAAAGCCTTTGACTGTGGCGATGTCGAGAT
GAATGCCTTCCTGCAGCGGTTCGCGCGGCAAGGGCATGAGCAGAACGCGGTGAAGTCGTTCTGTGCGGTTCCCGACGATG
CACCGGAAAAAATCCTTGGCTTCTACAGTCTGGCTCCGGCCTCGGTCGAACACCACGCGGTTCCTCCCCCGATGACGAAG
GGTCTGGCGCGACACGATGTGCCGGGCTTTCTGCTGGCGCGGCTTGCTGTCGACAAATCGGTGGCGGGCAGGGGGCTTGG
TGGTCAGCTTCTGCTCGCCGCCGCGCTGCGCTGCATCCGCGTTACTGAGGAAGTCGGCGGTGTGCTGATGATCATCGACG
CCAAAAGCAGTCGGGCCGCGAGCTGGTACGCGAGCTATGGCGCCGAGCCGCTGAATGACCGTCCAATGACGCTTGTCGTT
CCGCTCAAGACTTTTGCCGAAACCTTGAAGGCCAGCGGGCACCTCTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10149.75 Da
• Isoelectric Point: 10.4689

>AT116088 WP_129552540.1 NZ_CP034451:c112778-112500 [Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1]
MARAALDDTDRMNIRVKPEVKARLLRAAALRHTDLTSFVTQSALREAETVIAEADTIKVSERDFSRILELLDNPPKPNAK
LRAAAAALPKTL

Nucleotide

• Length: 279 bp

>AT116088 NZ_CP034451:c112778-112500 [Mesorhizobium sp. M3A.F.Ca.ET.080.04.2.1]
ATGGCCCGGGCAGCCCTTGATGATACTGATCGGATGAACATCCGGGTAAAGCCGGAGGTGAAGGCGCGCCTGTTGCGCGC
CGCAGCGCTTCGCCATACCGATCTCACCAGCTTCGTCACCCAGTCCGCGCTGCGCGAAGCCGAAACCGTAATCGCCGAAG
CTGACACCATAAAGGTATCCGAGCGGGATTTTAGCCGCATCCTTGAGCTTCTGGACAATCCTCCGAAGCCGAACGCGAAG
TTGCGTGCAGCGGCGGCCGCGCTTCCGAAGACCCTGTGA