Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) hicAB/HicA-HicA
Location 6263716..6264127 Replicon chromosome
Accession NZ_CP034449
Organism Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag EJ072_RS29855 Protein ID WP_126082529.1
Coordinates 6263927..6264127 (-) Length 67 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag EJ072_RS29850 Protein ID WP_126082528.1
Coordinates 6263716..6263922 (-) Length 69 a.a.

Genomic Context


EJ072_RS29820EJ072_RS29830EJ072_RS29825EJ072_RS29835EJ072_RS29840EJ072_RS29845EJ072_RS29850EJ072_RS29855EJ072_RS29860
Location: 6259046..6259831 (786 bp)
Type: Others
Protein ID: WP_126082522.1
Location: 6261139..6262260 (1122 bp)
Type: Others
Protein ID: WP_126082524.1
Location: 6259859..6260830 (972 bp)
Type: Others
Protein ID: WP_126082523.1
Location: 6262281..6262475 (195 bp)
Type: Others
Protein ID: WP_126082525.1
Location: 6262503..6262955 (453 bp)
Type: Others
Protein ID: WP_126082526.1
Location: 6263304..6263675 (372 bp)
Type: Others
Protein ID: WP_126082527.1
Location: 6263716..6263922 (207 bp)
Type: Antitoxin
Protein ID: WP_126082528.1
Location: 6263927..6264127 (201 bp)
Type: Toxin
Protein ID: WP_126082529.1
Location: 6264136..6267912 (3777 bp)
Type: Others
Protein ID: WP_126082530.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EJ072_RS298206259046..6259831+786WP_126082522.1phosphodiester glycosidase family protein-
EJ072_RS298256259859..6260830-972WP_126082523.1Tim44 domain-containing protein-
EJ072_RS298306261139..6262260+1122WP_126082524.1glycoside hydrolase family 25 protein-
EJ072_RS298356262281..6262475-195WP_126082525.1hypothetical protein-
EJ072_RS298406262503..6262955-453WP_126082526.1pyridoxamine 5'-phosphate oxidase family protein-
EJ072_RS298456263304..6263675-372WP_126082527.1VOC family protein-
EJ072_RS298506263716..6263922-207WP_126082528.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
EJ072_RS298556263927..6264127-201WP_126082529.1type II toxin-antitoxin system HicA family toxinToxin
EJ072_RS298606264136..6267912-3777WP_126082530.1vitamin B12-dependent ribonucleotide reductase-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 67 a.a.        Molecular weight: 7328.57 Da        Isoelectric Point: 10.7459

>T116086 WP_126082529.1 NZ_CP034449:c6264127-6263927 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
MPPRLTVREVIRMLEADGWYLVATKGSHRQYKHKIKAGRVTVAGKPSEEVAPGTLNSILKQSGLKE

Download         Length: 201 bp

>T116086 NZ_CP034449:c6264127-6263927 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
ATGCCGCCCCGGCTTACGGTCCGCGAAGTAATTCGCATGCTGGAGGCCGACGGTTGGTATCTGGTTGCAACCAAAGGCAG
CCATCGCCAATATAAGCACAAAATCAAAGCCGGCCGCGTCACCGTGGCCGGCAAGCCGTCTGAAGAGGTTGCGCCAGGAA
CGCTGAACAGCATTCTCAAGCAGTCCGGCTTAAAGGAGTGA

Antitoxin


Download         Length: 69 a.a.        Molecular weight: 7320.32 Da        Isoelectric Point: 4.3178

>AT116086 WP_126082528.1 NZ_CP034449:c6263922-6263716 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
MRYAVVIEKAGSNFSAYVPDLPGCIATGATVPEVENEIRDAIRFHIEGLRADGLEVPKAVSLAEYVEA

Download         Length: 207 bp

>AT116086 NZ_CP034449:c6263922-6263716 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
ATGCGCTACGCGGTGGTGATCGAAAAAGCCGGAAGCAACTTTTCCGCATATGTTCCTGACCTGCCAGGCTGCATCGCGAC
AGGTGCAACAGTGCCTGAAGTGGAGAACGAAATCCGCGACGCAATTCGTTTCCACATAGAGGGTCTGCGCGCCGATGGGC
TGGAAGTTCCCAAGGCAGTCAGTCTCGCTGAGTATGTTGAAGCATAG

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References