Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 3371544..3372199 Replicon chromosome
Accession NZ_CP034449
Organism Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EJ072_RS16235 Protein ID WP_126080570.1
Coordinates 3371544..3371945 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EJ072_RS16240 Protein ID WP_126080571.1
Coordinates 3371945..3372199 (-) Length 85 a.a.

Genomic Context

EJ072_RS16225EJ072_RS16250EJ072_RS16255EJ072_RS16215EJ072_RS16220EJ072_RS16230EJ072_RS16235EJ072_RS16240EJ072_RS16245
Location: 3369398..3370303 (906 bp)
Type: Others
Protein ID: WP_126080568.1
Location: 3373163..3375790 (2628 bp)
Type: Others
Protein ID: WP_126080573.1
Location: 3375777..3376358 (582 bp)
Type: Others
Protein ID: WP_126080574.1
Location: 3367017..3368051 (1035 bp)
Type: Others
Protein ID: WP_126080566.1
Location: 3368089..3369276 (1188 bp)
Type: Others
Protein ID: WP_126080567.1
Location: 3370365..3371414 (1050 bp)
Type: Others
Protein ID: WP_126080569.1
Location: 3371544..3371945 (402 bp)
Type: Toxin
Protein ID: WP_126080570.1
Location: 3371945..3372199 (255 bp)
Type: Antitoxin
Protein ID: WP_126080571.1
Location: 3372284..3372946 (663 bp)
Type: Others
Protein ID: WP_126080572.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EJ072_RS162153367017..3368051-1035WP_126080566.1aldo/keto reductase-
EJ072_RS162203368089..3369276-1188WP_126080567.1MFS transporter-
EJ072_RS162253369398..3370303+906WP_126080568.1LysR family transcriptional regulator-
EJ072_RS162303370365..3371414-1050WP_126080569.1aldo/keto reductase-
EJ072_RS162353371544..3371945-402WP_126080570.1type II toxin-antitoxin system VapC family toxinToxin
EJ072_RS162403371945..3372199-255WP_126080571.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
EJ072_RS162453372284..3372946-663WP_126080572.1YggS family pyridoxal phosphate-dependent enzyme-
EJ072_RS162503373163..3375790+2628WP_126080573.1leucine--tRNA ligase-
EJ072_RS162553375777..3376358+582WP_126080574.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-116)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-61)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14794.05 Da        Isoelectric Point: 5.9036

>T116085 WP_126080570.1 NZ_CP034449:c3371945-3371544 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
MYLLDTNVVSDVQRRLPKPTAWIASIDPASINLSVITLGEIERGIVKQRKIDPERAARLDIWLRELRRDNTDRILAITEE
VALAWGRITAGRTRGSADSLIAATALVHDLILVTRNVADFEGVGVTVLNPWEV

Download         Length: 402 bp

>T116085 NZ_CP034449:c3371945-3371544 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
ATGTATCTGCTGGACACGAACGTCGTGTCGGACGTGCAAAGACGGTTGCCTAAGCCGACTGCCTGGATAGCTTCGATTGA
TCCGGCGTCGATCAACCTTAGTGTCATTACGCTGGGTGAGATCGAGCGAGGAATCGTCAAACAGCGTAAGATCGACCCTG
AAAGGGCGGCTCGGCTCGATATCTGGCTGCGAGAACTTCGAAGAGACAATACGGACCGCATTCTCGCGATCACGGAGGAG
GTCGCTCTTGCCTGGGGTCGCATAACGGCGGGACGCACACGGGGGAGCGCCGACTCGCTTATCGCGGCGACCGCCCTCGT
GCACGACCTGATCCTGGTCACGCGAAACGTCGCCGACTTCGAGGGCGTCGGCGTTACAGTCCTCAATCCCTGGGAAGTCT
GA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9634.81 Da        Isoelectric Point: 5.8561

>AT116085 WP_126080571.1 NZ_CP034449:c3372199-3371945 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
MNWHLQDAKNNFSKVVQRARTEGPQTVTLRGERAAVVLSADDYDRLAGKKKSLVEYLLSGPGWDEEFDKEITRRSDTIIR
DIDL

Download         Length: 255 bp

>AT116085 NZ_CP034449:c3372199-3371945 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
ATGAACTGGCATCTTCAGGACGCGAAGAACAATTTCTCGAAAGTGGTCCAGCGGGCGCGAACCGAGGGACCGCAGACCGT
GACACTTCGCGGCGAACGTGCCGCGGTCGTCCTCTCCGCAGACGACTACGATCGCTTGGCCGGGAAGAAGAAATCGCTCG
TCGAGTACCTATTGAGCGGTCCAGGTTGGGACGAGGAGTTTGACAAGGAAATCACCCGTCGCTCGGACACGATTATCCGG
GACATTGATCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References