Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 1147323..1148340 Replicon chromosome
Accession NZ_CP034449
Organism Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag EJ072_RS05555 Protein ID WP_210211652.1
Coordinates 1147323..1147898 (-) Length 192 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag EJ072_RS05560 Protein ID WP_126078907.1
Coordinates 1147894..1148340 (-) Length 149 a.a.

Genomic Context

EJ072_RS05545EJ072_RS05550EJ072_RS35825EJ072_RS05555EJ072_RS05560EJ072_RS05565EJ072_RS05570EJ072_RS05575EJ072_RS05580
Location: 1143868..1144386 (519 bp)
Type: Others
Protein ID: WP_189343224.1
Location: 1144677..1146161 (1485 bp)
Type: Others
Protein ID: WP_126078905.1
Location: 1147144..1147290 (147 bp)
Type: Others
Protein ID: WP_189343225.1
Location: 1147323..1147898 (576 bp)
Type: Toxin
Protein ID: WP_210211652.1
Location: 1147894..1148340 (447 bp)
Type: Antitoxin
Protein ID: WP_126078907.1
Location: 1148844..1149022 (179 bp)
Type: Others
Protein ID: Protein_1093
Location: 1149031..1149996 (966 bp)
Type: Others
Protein ID: WP_126078908.1
Location: 1150227..1150406 (180 bp)
Type: Others
Protein ID: Protein_1095
Location: 1150474..1152036 (1563 bp)
Type: Others
Protein ID: WP_126078909.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EJ072_RS055451143868..1144386+519WP_189343224.1Mov34/MPN/PAD-1 family protein-
EJ072_RS055501144677..1146161-1485WP_126078905.1hypothetical protein-
EJ072_RS358251147144..1147290-147WP_189343225.1hypothetical protein-
EJ072_RS055551147323..1147898-576WP_210211652.1PIN domain-containing proteinToxin
EJ072_RS055601147894..1148340-447WP_126078907.1helix-turn-helix domain-containing proteinAntitoxin
EJ072_RS055651148844..1149022-179Protein_1093cold-shock protein-
EJ072_RS055701149031..1149996-966WP_126078908.1DUF4238 domain-containing protein-
EJ072_RS055751150227..1150406-180Protein_1095aldehyde-activating protein-
EJ072_RS055801150474..1152036-1563WP_126078909.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--1140603..115922718624


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

Helix-turn-helix domain, group 17

(78-124)


Sequences

Toxin        


Download         Length: 192 a.a.        Molecular weight: 21909.17 Da        Isoelectric Point: 5.6593

>T116084 WP_210211652.1 NZ_CP034449:c1147898-1147323 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
IRESSYTVILDACVLYPAPLRDFLMELAAGGLFRAKWTEQIHDEWIRNVLKNREDLKPEQLLRTKQLMNQAVPDCTVEGY
EDLIEGLKLPDGDDRHVLAAAIHAACDAIITFNLKDFPRDYLAKFQIELLHPDEFLFHQFGLNTAAVVVAAQRCRKRLKN
PPRTAEEYLDTLERQGLTKTVTELRNYASVI

Download         Length: 576 bp

>T116084 NZ_CP034449:c1147898-1147323 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
ATTAGGGAGTCCAGTTACACCGTCATTCTCGACGCTTGCGTATTATACCCGGCCCCGCTGCGAGACTTCCTGATGGAGCT
TGCAGCGGGAGGGCTATTTCGCGCGAAATGGACTGAACAAATCCATGACGAATGGATTCGCAACGTGCTTAAGAATCGCG
AGGACCTTAAGCCCGAGCAGCTTTTGCGGACAAAACAACTGATGAACCAGGCAGTGCCTGACTGCACGGTTGAAGGCTAC
GAGGACCTGATTGAGGGTCTAAAACTACCTGACGGTGACGACAGACATGTTCTCGCAGCCGCTATCCATGCGGCTTGTGA
CGCCATCATCACTTTCAATCTGAAAGACTTTCCGCGTGACTATCTCGCCAAGTTCCAGATAGAGCTTCTGCATCCGGACG
AATTTCTGTTCCATCAGTTTGGCCTGAATACAGCCGCCGTCGTGGTAGCGGCCCAGCGTTGTCGTAAACGTTTGAAAAAC
CCTCCGAGAACGGCAGAGGAATACCTCGATACCCTCGAGCGGCAAGGGCTCACCAAAACGGTGACCGAACTCCGAAACTA
CGCCTCGGTCATTTAG

Antitoxin


Download         Length: 149 a.a.        Molecular weight: 16841.17 Da        Isoelectric Point: 5.5937

>AT116084 WP_126078907.1 NZ_CP034449:c1148340-1147894 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
MTTLLERPILPSADDAELAAEASRHLSRAKHEDAELRIQVDGGEMLRLPKAVNDLLYHLLTEMAQGNAVTLFPIHAELTT
QEAADYLNVSRPYLVRLLEEGKVKFHMVGTHRRVKFRDLDAFRRSTEEERQRVMDELAAQAQDLGMGY

Download         Length: 447 bp

>AT116084 NZ_CP034449:c1148340-1147894 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
ATGACTACGCTGCTCGAACGACCGATATTGCCTTCGGCCGACGATGCCGAATTGGCTGCGGAGGCCAGCCGCCACCTTTC
TAGAGCCAAGCACGAGGATGCTGAATTGCGCATCCAAGTGGATGGGGGAGAGATGCTGCGCCTGCCTAAGGCAGTGAACG
ATCTTCTCTATCATTTGCTCACCGAAATGGCACAGGGTAATGCCGTTACCCTGTTCCCAATCCATGCCGAGCTGACCACA
CAGGAGGCTGCTGACTACCTGAATGTGTCACGTCCTTATCTTGTTCGACTCCTCGAGGAGGGTAAGGTCAAGTTCCATAT
GGTAGGAACTCATCGACGGGTCAAATTCCGAGATTTAGATGCATTCCGTAGGTCAACTGAGGAAGAGCGTCAGCGCGTAA
TGGATGAACTCGCAGCCCAAGCGCAGGATTTGGGGATGGGCTATTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References