Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yafQ-relB/YafQ-RelB
Location 846459..846990 Replicon chromosome
Accession NZ_CP034449
Organism Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag EJ072_RS04155 Protein ID WP_126078686.1
Coordinates 846718..846990 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag EJ072_RS04150 Protein ID WP_126078685.1
Coordinates 846459..846716 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJ072_RS04140 843278..844243 + 966 WP_126078684.1 sugar-binding transcriptional regulator -
EJ072_RS04145 844325..846379 + 2055 WP_126083495.1 bifunctional aldolase/short-chain dehydrogenase -
EJ072_RS04150 846459..846716 + 258 WP_126078685.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
EJ072_RS04155 846718..846990 + 273 WP_126078686.1 type II toxin-antitoxin system YafQ family toxin Toxin
EJ072_RS04160 847207..848271 + 1065 WP_126078687.1 D-alanine--D-alanine ligase -
EJ072_RS04165 848285..849790 - 1506 WP_126078688.1 winged helix-turn-helix domain-containing tetratricopeptide repeat protein -
EJ072_RS04170 850099..850290 + 192 WP_126083496.1 DUF1127 domain-containing protein -
EJ072_RS04175 850367..851419 - 1053 WP_042638932.1 substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(7-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(6-82)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10569.21 Da        Isoelectric Point: 9.9120

>T116083 WP_126078686.1 NZ_CP034449:846718-846990 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
MLIPVRSGQFRRDVKRMEKRGKDLGKLRQILVHLIGEHELPPIYKDHPLKGDWKGYRDAHIEPDWLLIYRVANGELQLAR
TGSHSDLFNE

Download         Length: 273 bp

>T116083 NZ_CP034449:846718-846990 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
ATGTTGATCCCCGTTCGCTCCGGGCAATTCCGCCGGGATGTGAAGCGTATGGAGAAGCGTGGCAAGGATCTTGGCAAGTT
GCGTCAGATTTTAGTTCACCTGATCGGCGAGCATGAACTGCCGCCGATCTACAAAGACCATCCGCTGAAAGGCGACTGGA
AGGGCTATCGTGACGCTCACATCGAACCGGATTGGCTTTTGATCTATCGCGTGGCGAATGGAGAGCTGCAGCTTGCACGA
ACCGGCTCGCATTCGGACCTCTTCAACGAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9223.63 Da        Isoelectric Point: 6.3276

>AT116083 WP_126078685.1 NZ_CP034449:846459-846716 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
MASDTVVRARIDTATKDQATEALAAMGLSVSDAIRLLLVRVAADKEFPFPVKVPNTTTRKAMAELEKGKGKRFASADELF
NDLEI

Download         Length: 258 bp

>AT116083 NZ_CP034449:846459-846716 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
ATGGCATCAGATACGGTAGTCCGCGCTCGCATCGATACCGCAACGAAGGATCAGGCTACGGAAGCCTTGGCGGCCATGGG
GTTGTCGGTTTCCGACGCCATTCGCCTGCTGTTGGTCCGTGTCGCCGCGGACAAAGAATTTCCCTTTCCGGTGAAAGTCC
CGAACACAACCACGCGAAAGGCCATGGCCGAATTGGAGAAGGGCAAGGGCAAGCGGTTCGCTTCGGCCGACGAGCTATTC
AACGATCTGGAAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References