Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 439962..440728 Replicon chromosome
Accession NZ_CP034449
Organism Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag EJ072_RS02365 Protein ID WP_126078401.1
Coordinates 440243..440728 (+) Length 162 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag EJ072_RS02360 Protein ID WP_126078400.1
Coordinates 439962..440243 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJ072_RS02340 436390..436632 + 243 WP_126083468.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
EJ072_RS02345 437010..437492 - 483 WP_126078398.1 transcription elongation factor GreA -
EJ072_RS02350 437600..438976 + 1377 WP_126078399.1 TIGR03808 family TAT-translocated repetitive protein -
EJ072_RS02355 438973..439784 - 812 Protein_463 methyltransferase domain-containing protein -
EJ072_RS02360 439962..440243 + 282 WP_126078400.1 DUF1778 domain-containing protein Antitoxin
EJ072_RS02365 440243..440728 + 486 WP_126078401.1 GNAT family N-acetyltransferase Toxin
EJ072_RS02370 440812..441813 - 1002 WP_126078402.1 asparaginase -
EJ072_RS02375 441863..443029 - 1167 WP_126078403.1 acetyl-CoA acetyltransferase -
EJ072_RS02380 443218..443808 + 591 WP_126078404.1 transcriptional regulator BetI -
EJ072_RS02385 443805..445334 + 1530 WP_126078405.1 choline-sulfatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-142)

Antitoxin

Vibrio phage ICP1, Orf50

(3-78)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17242.71 Da        Isoelectric Point: 9.4572

>T116082 WP_126078401.1 NZ_CP034449:440243-440728 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
MLSAPVLLADSHDLDLFQSGTDSLDQWLRRRARANQVSGASRTYVIAEGTRVVGYYCLSSGGLDLADAPGSIRRNMPDPV
PMAVLGRLAVDANWQSKGPGVALLQDAVLRTSQAAAILGIRGLLVHAISDEAKTFYERYGFQASPKNPMTLVLSLKTARS
G

Download         Length: 486 bp

>T116082 NZ_CP034449:440243-440728 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
ATGCTATCGGCACCGGTCCTTCTCGCCGATAGCCACGACCTCGACCTTTTTCAAAGCGGGACCGACAGCCTCGATCAATG
GCTTCGACGGCGGGCGCGTGCCAATCAGGTCAGCGGCGCGTCCAGAACCTATGTGATTGCGGAAGGCACGCGCGTCGTTG
GCTATTATTGCCTTTCATCAGGTGGACTTGATCTCGCAGATGCTCCCGGTTCGATCCGGCGCAATATGCCGGATCCCGTG
CCCATGGCTGTGCTTGGCCGTTTGGCTGTCGATGCAAACTGGCAGAGCAAGGGCCCCGGCGTCGCCCTGCTTCAGGACGC
GGTGCTGCGGACCAGCCAAGCGGCCGCCATTCTCGGCATTCGCGGTCTCCTGGTTCATGCCATATCGGATGAAGCCAAGA
CGTTTTATGAACGCTATGGCTTCCAGGCTTCGCCAAAGAATCCGATGACTTTGGTGCTGTCGCTGAAGACGGCTAGGTCA
GGATGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10669.07 Da        Isoelectric Point: 7.2023

>AT116082 WP_126078400.1 NZ_CP034449:439962-440243 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
MATKNQDSHAKPVNLRIREDVRSLIDRAAKIRGKTRSDFMIEAAYRAAEDTLLDQTLVKVDAESYQHYLDILDQPPRGEG
FARLMNAPKPWQD

Download         Length: 282 bp

>AT116082 NZ_CP034449:439962-440243 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
ATGGCCACCAAAAACCAGGACAGCCACGCCAAGCCCGTCAACCTGCGCATCCGCGAGGATGTCCGCAGCCTGATCGACCG
CGCCGCGAAGATACGCGGCAAGACCCGCTCCGACTTCATGATCGAGGCCGCCTACCGCGCGGCCGAAGACACGCTGCTCG
ACCAGACGCTCGTCAAGGTCGATGCCGAAAGCTATCAGCATTATCTCGATATCCTCGACCAGCCGCCGCGCGGCGAGGGA
TTTGCCCGGCTGATGAATGCGCCCAAGCCCTGGCAGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References