Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 439962..440728 Replicon chromosome
Accession NZ_CP034449
Organism Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag EJ072_RS02365 Protein ID WP_126078401.1
Coordinates 440243..440728 (+) Length 162 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag EJ072_RS02360 Protein ID WP_126078400.1
Coordinates 439962..440243 (+) Length 94 a.a.

Genomic Context

EJ072_RS02340EJ072_RS02350EJ072_RS02360EJ072_RS02365EJ072_RS02380EJ072_RS02385EJ072_RS02345EJ072_RS02355EJ072_RS02370EJ072_RS02375
Location: 436390..436632 (243 bp)
Type: Others
Protein ID: WP_126083468.1
Location: 437600..438976 (1377 bp)
Type: Others
Protein ID: WP_126078399.1
Location: 439962..440243 (282 bp)
Type: Antitoxin
Protein ID: WP_126078400.1
Location: 440243..440728 (486 bp)
Type: Toxin
Protein ID: WP_126078401.1
Location: 443218..443808 (591 bp)
Type: Others
Protein ID: WP_126078404.1
Location: 443805..445334 (1530 bp)
Type: Others
Protein ID: WP_126078405.1
Location: 437010..437492 (483 bp)
Type: Others
Protein ID: WP_126078398.1
Location: 438973..439784 (812 bp)
Type: Others
Protein ID: Protein_463
Location: 440812..441813 (1002 bp)
Type: Others
Protein ID: WP_126078402.1
Location: 441863..443029 (1167 bp)
Type: Others
Protein ID: WP_126078403.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EJ072_RS02340436390..436632+243WP_126083468.1AbrB/MazE/SpoVT family DNA-binding domain-containing protein-
EJ072_RS02345437010..437492-483WP_126078398.1transcription elongation factor GreA-
EJ072_RS02350437600..438976+1377WP_126078399.1TIGR03808 family TAT-translocated repetitive protein-
EJ072_RS02355438973..439784-812Protein_463methyltransferase domain-containing protein-
EJ072_RS02360439962..440243+282WP_126078400.1DUF1778 domain-containing proteinAntitoxin
EJ072_RS02365440243..440728+486WP_126078401.1GNAT family N-acetyltransferaseToxin
EJ072_RS02370440812..441813-1002WP_126078402.1asparaginase-
EJ072_RS02375441863..443029-1167WP_126078403.1acetyl-CoA acetyltransferase-
EJ072_RS02380443218..443808+591WP_126078404.1transcriptional regulator BetI-
EJ072_RS02385443805..445334+1530WP_126078405.1choline-sulfatase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-142)

Antitoxin

Vibrio phage ICP1, Orf50

(3-78)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17242.71 Da        Isoelectric Point: 9.4572

>T116082 WP_126078401.1 NZ_CP034449:440243-440728 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
MLSAPVLLADSHDLDLFQSGTDSLDQWLRRRARANQVSGASRTYVIAEGTRVVGYYCLSSGGLDLADAPGSIRRNMPDPV
PMAVLGRLAVDANWQSKGPGVALLQDAVLRTSQAAAILGIRGLLVHAISDEAKTFYERYGFQASPKNPMTLVLSLKTARS
G

Download         Length: 486 bp

>T116082 NZ_CP034449:440243-440728 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
ATGCTATCGGCACCGGTCCTTCTCGCCGATAGCCACGACCTCGACCTTTTTCAAAGCGGGACCGACAGCCTCGATCAATG
GCTTCGACGGCGGGCGCGTGCCAATCAGGTCAGCGGCGCGTCCAGAACCTATGTGATTGCGGAAGGCACGCGCGTCGTTG
GCTATTATTGCCTTTCATCAGGTGGACTTGATCTCGCAGATGCTCCCGGTTCGATCCGGCGCAATATGCCGGATCCCGTG
CCCATGGCTGTGCTTGGCCGTTTGGCTGTCGATGCAAACTGGCAGAGCAAGGGCCCCGGCGTCGCCCTGCTTCAGGACGC
GGTGCTGCGGACCAGCCAAGCGGCCGCCATTCTCGGCATTCGCGGTCTCCTGGTTCATGCCATATCGGATGAAGCCAAGA
CGTTTTATGAACGCTATGGCTTCCAGGCTTCGCCAAAGAATCCGATGACTTTGGTGCTGTCGCTGAAGACGGCTAGGTCA
GGATGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10669.07 Da        Isoelectric Point: 7.2023

>AT116082 WP_126078400.1 NZ_CP034449:439962-440243 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
MATKNQDSHAKPVNLRIREDVRSLIDRAAKIRGKTRSDFMIEAAYRAAEDTLLDQTLVKVDAESYQHYLDILDQPPRGEG
FARLMNAPKPWQD

Download         Length: 282 bp

>AT116082 NZ_CP034449:439962-440243 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
ATGGCCACCAAAAACCAGGACAGCCACGCCAAGCCCGTCAACCTGCGCATCCGCGAGGATGTCCGCAGCCTGATCGACCG
CGCCGCGAAGATACGCGGCAAGACCCGCTCCGACTTCATGATCGAGGCCGCCTACCGCGCGGCCGAAGACACGCTGCTCG
ACCAGACGCTCGTCAAGGTCGATGCCGAAAGCTATCAGCATTATCTCGATATCCTCGACCAGCCGCCGCGCGGCGAGGGA
TTTGCCCGGCTGATGAATGCGCCCAAGCCCTGGCAGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References