Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 213285..213880 Replicon chromosome
Accession NZ_CP034449
Organism Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag EJ072_RS01250 Protein ID WP_126078229.1
Coordinates 213593..213880 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A3S9DEM1
Locus tag EJ072_RS01245 Protein ID WP_042637981.1
Coordinates 213285..213590 (-) Length 102 a.a.

Genomic Context

EJ072_RS01230EJ072_RS01235EJ072_RS01240EJ072_RS01245EJ072_RS01250EJ072_RS01255EJ072_RS01260EJ072_RS01265EJ072_RS01270
Location: 210491..211402 (912 bp)
Type: Others
Protein ID: WP_126078226.1
Location: 211531..212031 (501 bp)
Type: Others
Protein ID: WP_126078227.1
Location: 212122..213279 (1158 bp)
Type: Others
Protein ID: WP_126078228.1
Location: 213285..213590 (306 bp)
Type: Antitoxin
Protein ID: WP_042637981.1
Location: 213593..213880 (288 bp)
Type: Toxin
Protein ID: WP_126078229.1
Location: 213933..214928 (996 bp)
Type: Others
Protein ID: WP_126078230.1
Location: 214925..216091 (1167 bp)
Type: Others
Protein ID: WP_126078231.1
Location: 216067..217323 (1257 bp)
Type: Others
Protein ID: WP_126078232.1
Location: 217320..218144 (825 bp)
Type: Others
Protein ID: WP_126078233.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EJ072_RS01230210491..211402+912WP_126078226.1glycoside hydrolase family 26 protein-
EJ072_RS01235211531..212031+501WP_126078227.1DUF995 domain-containing protein-
EJ072_RS01240212122..213279+1158WP_126078228.1hypothetical protein-
EJ072_RS01245213285..213590-306WP_042637981.1putative addiction module antidote proteinAntitoxin
EJ072_RS01250213593..213880-288WP_126078229.1type II toxin-antitoxin system RelE/ParE family toxinToxin
EJ072_RS01255213933..214928-996WP_126078230.1Rieske 2Fe-2S domain-containing protein-
EJ072_RS01260214925..216091-1167WP_126078231.1GNAT family N-acetyltransferase-
EJ072_RS01265216067..217323-1257WP_126078232.1CoF synthetase-
EJ072_RS01270217320..218144-825WP_126078233.1MBL fold metallo-hydrolase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-91)

Antitoxin

Uncharacterized protein HI1420

(5-93)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10689.41 Da        Isoelectric Point: 10.2219

>T116081 WP_126078229.1 NZ_CP034449:c213880-213593 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
MIEVRQTADFTNWLDGLRDAAARLRIAARIRRVEIGNIGDVKYFDGIGELRIDHGPGYRLYFVKIGNAVIILLCGGDKSS
QRRDIAKAKQMAKEI

Download         Length: 288 bp

>T116081 NZ_CP034449:c213880-213593 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
ATGATCGAGGTCCGGCAGACGGCCGATTTCACCAACTGGCTGGACGGACTTCGCGACGCTGCGGCTCGCCTGCGCATCGC
TGCCCGCATTCGTCGGGTCGAAATCGGCAACATCGGTGATGTCAAATATTTCGATGGCATCGGCGAACTTCGGATCGACC
ATGGCCCAGGTTACCGGCTCTACTTTGTGAAGATCGGAAACGCCGTGATCATCCTGCTCTGTGGCGGCGACAAGTCCAGC
CAAAGGCGCGACATCGCCAAGGCGAAACAAATGGCAAAGGAGATATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10697.30 Da        Isoelectric Point: 4.6158

>AT116081 WP_042637981.1 NZ_CP034449:c213590-213285 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
MPLETTRFDILDYLKTPEDRLAYIEAAFEDGDPALITHALGDVARSIGMTAVAKEAGVTREALYKALSEKGDPRLSTLLG
VTKALGLQLDVKPIGPGSLGA

Download         Length: 306 bp

>AT116081 NZ_CP034449:c213590-213285 [Mesorhizobium sp. M2A.F.Ca.ET.046.03.2.1]
ATGCCTCTCGAAACCACTCGCTTCGACATCCTCGATTACCTGAAAACCCCGGAGGATCGCTTGGCCTACATCGAGGCTGC
CTTCGAGGATGGTGATCCTGCGCTCATCACGCATGCGTTGGGCGATGTAGCGCGCTCCATAGGCATGACGGCTGTGGCGA
AAGAAGCTGGCGTCACGCGTGAGGCGCTCTACAAGGCATTGAGCGAAAAGGGCGACCCTCGCCTCAGCACACTGCTGGGT
GTCACCAAGGCGCTTGGTCTGCAACTTGACGTGAAACCTATCGGCCCTGGCTCGCTCGGGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A3S9DEM1

References