Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 6295439..6296205 Replicon chromosome
Accession NZ_CP034448
Organism Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag EJ071_RS31420 Protein ID WP_126101321.1
Coordinates 6295720..6296205 (+) Length 162 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag EJ071_RS31415 Protein ID WP_126101320.1
Coordinates 6295439..6295720 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJ071_RS31395 6290487..6292610 + 2124 WP_126101317.1 methylmalonyl-CoA mutase -
EJ071_RS31400 6292671..6292913 + 243 WP_126102796.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
EJ071_RS31405 6293294..6293776 - 483 WP_126101318.1 transcription elongation factor GreA -
EJ071_RS31410 6293883..6295259 + 1377 WP_126101319.1 TIGR03808 family TAT-translocated repetitive protein -
EJ071_RS31415 6295439..6295720 + 282 WP_126101320.1 DUF1778 domain-containing protein Antitoxin
EJ071_RS31420 6295720..6296205 + 486 WP_126101321.1 GNAT family N-acetyltransferase Toxin
EJ071_RS31425 6296255..6297259 - 1005 WP_126101322.1 asparaginase -
EJ071_RS31430 6297316..6298482 - 1167 WP_126101323.1 acetyl-CoA acetyltransferase -
EJ071_RS31435 6298670..6299260 + 591 WP_126101324.1 transcriptional regulator BetI -
EJ071_RS31440 6299257..6300786 + 1530 WP_126101325.1 choline-sulfatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-142)

Antitoxin

Vibrio phage ICP1, Orf50

(14-77)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17143.72 Da        Isoelectric Point: 9.4398

>T116079 WP_126101321.1 NZ_CP034448:6295720-6296205 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
MLSAPALLADSHELDLFQSGTDSLDQWLRRRARANQVSGASRTYVIAESARVVGYYCLSSGGLDLADAPGSIRRNMPDPV
PMAVLGRLAVDASWQGKGLGVALLQDAVLRTGQAAAILGIRGLLVHAISDEAKAFYERYGFQASPKSPMTLVLSLKMAQK
G

Download         Length: 486 bp

>T116079 NZ_CP034448:6295720-6296205 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
ATGCTATCGGCACCAGCCCTTCTTGCCGATAGTCACGAACTCGACCTTTTTCAAAGCGGGACCGACAGCCTGGATCAATG
GCTTCGACGGCGGGCGCGCGCCAATCAAGTCAGCGGGGCGTCCAGAACCTATGTGATTGCAGAAAGCGCGCGCGTTGTTG
GTTACTATTGCCTTTCATCAGGCGGACTTGACCTGGCGGATGCGCCCGGTTCGATCCGGCGTAATATGCCCGATCCCGTG
CCCATGGCCGTACTTGGCCGCTTGGCTGTCGATGCAAGCTGGCAGGGAAAGGGCCTGGGCGTCGCTTTGTTGCAGGACGC
GGTGCTGCGGACCGGTCAAGCGGCAGCCATTCTCGGCATTCGTGGTCTCTTGGTTCACGCCATATCGGACGAAGCCAAAG
CGTTTTATGAGCGGTATGGCTTCCAGGCTTCTCCAAAAAGTCCGATGACTTTGGTGCTATCGCTGAAGATGGCTCAGAAG
GGGTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10682.16 Da        Isoelectric Point: 8.5141

>AT116079 WP_126101320.1 NZ_CP034448:6295439-6295720 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
MATKNQDTHAKPVNLRIREDVRILIDRAAKIRGKTRSDFMIDAAYRAAEDTLLDQTLVKVDAESYQHYLDILDRPPSGEG
FARLMNAPKPWRD

Download         Length: 282 bp

>AT116079 NZ_CP034448:6295439-6295720 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
ATGGCCACGAAAAACCAGGATACCCACGCCAAGCCCGTCAATCTGCGCATCCGCGAGGATGTCCGCATCCTGATCGACCG
CGCCGCGAAGATACGCGGCAAGACCCGCTCCGACTTCATGATCGACGCCGCTTATCGTGCAGCCGAAGACACGCTGCTCG
ACCAGACGCTCGTCAAGGTCGATGCCGAAAGCTATCAGCATTATCTCGATATCCTCGATCGGCCACCGAGCGGCGAGGGA
TTTGCCCGTCTGATGAATGCGCCTAAGCCTTGGCGGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References