Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 6159710..6160512 Replicon chromosome
Accession NZ_CP034448
Organism Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag EJ071_RS30765 Protein ID WP_126101211.1
Coordinates 6159985..6160512 (+) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag EJ071_RS30760 Protein ID WP_126102787.1
Coordinates 6159710..6159988 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJ071_RS30745 6155026..6155778 - 753 WP_126101208.1 DNA repair protein RecO -
EJ071_RS30750 6156041..6156844 + 804 WP_126101209.1 CPBP family intramembrane metalloprotease -
EJ071_RS30755 6156917..6159559 + 2643 WP_189521298.1 mechanosensitive ion channel -
EJ071_RS30760 6159710..6159988 + 279 WP_126102787.1 DUF1778 domain-containing protein Antitoxin
EJ071_RS30765 6159985..6160512 + 528 WP_126101211.1 GNAT family N-acetyltransferase Toxin
EJ071_RS30770 6160519..6161412 - 894 WP_126101212.1 aminoglycoside phosphotransferase family protein -
EJ071_RS30775 6161449..6163125 - 1677 WP_126101213.1 winged helix-turn-helix domain-containing protein -
EJ071_RS30780 6163212..6163565 + 354 WP_126101214.1 hypothetical protein -
EJ071_RS30785 6163665..6164585 - 921 WP_126101215.1 GTPase Era -
EJ071_RS30790 6164582..6165298 - 717 WP_126101216.1 ribonuclease III -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(11-87)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 18986.76 Da        Isoelectric Point: 8.7358

>T116078 WP_126101211.1 NZ_CP034448:6159985-6160512 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
MILPRWREEPISKSHDRASFDCGDEQMNDFLRRFARQSHEQNASKTFCAVENANPDRVLGFYTIAPSAVAHEQVHATLTK
GLARHEVSGFKLARLATDLTVAGQGLGGQLLAAAALRCLRVAAEGGGLLLIIDAKSERAANWYRGYGAEPLTGKPLTLVM
PLATFAADLRAKSLL

Download         Length: 528 bp

>T116078 NZ_CP034448:6159985-6160512 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
ATGATCCTGCCGCGTTGGCGAGAGGAGCCGATCTCGAAATCGCATGATCGCGCGTCCTTTGATTGCGGCGACGAGCAGAT
GAATGATTTTCTGCGGCGCTTCGCCAGGCAGAGCCATGAACAGAATGCTTCGAAGACATTTTGCGCCGTCGAGAACGCGA
ACCCAGACCGCGTTCTCGGCTTCTATACGATCGCACCCTCCGCCGTTGCTCATGAGCAAGTGCACGCGACCCTAACGAAG
GGGCTCGCCCGACACGAGGTGTCCGGATTCAAGCTGGCCCGCCTGGCGACCGATCTGACGGTTGCCGGGCAAGGGCTCGG
AGGTCAGCTGCTCGCTGCGGCGGCCCTGCGTTGCCTGCGTGTCGCGGCCGAGGGAGGCGGCCTGCTGCTCATCATCGACG
CCAAGAGCGAGCGCGCCGCGAATTGGTATCGCGGATATGGCGCCGAGCCCCTCACCGGAAAGCCGCTGACACTTGTCATG
CCGCTGGCGACCTTCGCCGCCGATCTCAGGGCCAAAAGCCTGTTGTAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10298.10 Da        Isoelectric Point: 10.1892

>AT116078 WP_126102787.1 NZ_CP034448:6159710-6159988 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
MPKPASDKTERFNIRIRPAQKAMIARAAALSHKDMTDFILDKVLPEAEAVIKAIEKTEVSDRDFKRILELLEHPPKPNAK
LRAAIAALPDTI

Download         Length: 279 bp

>AT116078 NZ_CP034448:6159710-6159988 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
ATGCCCAAGCCAGCCAGCGACAAAACCGAACGCTTCAATATCCGCATACGGCCCGCGCAAAAGGCGATGATCGCCCGCGC
GGCGGCGCTGTCGCATAAGGACATGACCGACTTTATCCTCGACAAGGTGCTGCCTGAGGCGGAAGCCGTGATCAAAGCGA
TCGAAAAGACCGAAGTGTCGGATCGCGACTTCAAACGCATCCTCGAACTGCTTGAGCATCCCCCGAAGCCAAATGCGAAA
TTGCGGGCTGCCATTGCGGCTCTTCCCGATACGATATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References