Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 5758791..5759808 Replicon chromosome
Accession NZ_CP034448
Organism Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag EJ071_RS28535 Protein ID WP_126100837.1
Coordinates 5758791..5759369 (-) Length 193 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag EJ071_RS28540 Protein ID WP_126100838.1
Coordinates 5759365..5759808 (-) Length 148 a.a.

Genomic Context

EJ071_RS28510EJ071_RS28515EJ071_RS28520EJ071_RS28525EJ071_RS28530EJ071_RS28555EJ071_RS28535EJ071_RS28540EJ071_RS28545EJ071_RS28550EJ071_RS28560
Location: 5754555..5754791 (237 bp)
Type: Others
Protein ID: WP_126100832.1
Location: 5755056..5755649 (594 bp)
Type: Others
Protein ID: WP_126100833.1
Location: 5755723..5756949 (1227 bp)
Type: Others
Protein ID: WP_126100834.1
Location: 5756967..5758280 (1314 bp)
Type: Others
Protein ID: WP_189521245.1
Location: 5758292..5758732 (441 bp)
Type: Others
Protein ID: WP_210211944.1
Location: 5763233..5764159 (927 bp)
Type: Others
Protein ID: WP_126102758.1
Location: 5758791..5759369 (579 bp)
Type: Toxin
Protein ID: WP_126100837.1
Location: 5759365..5759808 (444 bp)
Type: Antitoxin
Protein ID: WP_126100838.1
Location: 5759946..5760662 (717 bp)
Type: Others
Protein ID: WP_126102757.1
Location: 5761602..5763098 (1497 bp)
Type: Others
Protein ID: WP_126100839.1
Location: 5764333..5764629 (297 bp)
Type: Others
Protein ID: WP_126100840.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EJ071_RS285105754555..5754791+237WP_126100832.1DUF1127 domain-containing protein-
EJ071_RS285155755056..5755649+594WP_126100833.1OsmC family protein-
EJ071_RS285205755723..5756949+1227WP_126100834.1NAD(P)/FAD-dependent oxidoreductase-
EJ071_RS285255756967..5758280+1314WP_189521245.1NAD(P)/FAD-dependent oxidoreductase-
EJ071_RS285305758292..5758732+441WP_210211944.1MaoC family dehydratase N-terminal domain-containing protein-
EJ071_RS285355758791..5759369-579WP_126100837.1PIN domain-containing proteinToxin
EJ071_RS285405759365..5759808-444WP_126100838.1helix-turn-helix domain-containing proteinAntitoxin
EJ071_RS285455759946..5760662-717WP_126102757.1alpha/beta hydrolase-
EJ071_RS285505761602..5763098-1497WP_126100839.1MFS transporter-
EJ071_RS285555763233..5764159+927WP_126102758.1LysR family transcriptional regulator-
EJ071_RS285605764333..5764629-297WP_126100840.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-115)

Antitoxin

SinI-like, DNA-binding domain

(77-121)


Sequences

Toxin        


Download         Length: 193 a.a.        Molecular weight: 21758.96 Da        Isoelectric Point: 6.0980

>T116077 WP_126100837.1 NZ_CP034448:c5759369-5758791 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
IKTSSYTAVLDACVLYPAPLRDLLVELAAGGGLYRAKWTEQIHDEWIRNLLQNRPDLKPEQIYRTRDLMNRAVLDCLVDG
YQDLLPSLALPDENDRHVLAAAIVSAFDAIVTFNFRDFPKPVLDKYQLDLIHPDDFIFQQFGIDNAAVLVSVQRCRARLR
NPPRSAAEYLDTLERQGLPKTVGHLRAYAGVI

Download         Length: 579 bp

>T116077 NZ_CP034448:c5759369-5758791 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
ATTAAGACCTCTTCCTACACCGCCGTCCTGGACGCTTGCGTTCTTTATCCAGCCCCGCTGCGGGATCTTCTCGTCGAGCT
TGCCGCGGGAGGTGGCCTCTATCGGGCCAAATGGACAGAACAGATCCATGACGAGTGGATACGCAATCTCTTACAGAACC
GTCCGGATCTCAAGCCGGAGCAGATTTACAGAACACGCGACCTGATGAATCGCGCCGTCCTGGATTGTCTGGTTGACGGC
TATCAGGACTTGCTGCCGAGTCTGGCGCTTCCCGACGAAAATGACCGCCATGTTCTGGCTGCGGCCATCGTCTCGGCGTT
CGATGCGATCGTCACCTTCAATTTCAGGGATTTTCCCAAGCCCGTTCTCGATAAATACCAGTTGGACCTGATCCACCCCG
ACGATTTCATTTTCCAGCAGTTCGGCATCGACAATGCTGCCGTATTGGTCTCGGTTCAAAGATGTCGCGCACGTCTGAGG
AACCCTCCCAGGAGTGCCGCCGAGTACCTCGACACGCTGGAGAGGCAGGGCCTGCCCAAAACGGTTGGCCATCTGCGCGC
TTATGCTGGAGTGATCTAG

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16438.91 Da        Isoelectric Point: 7.2054

>AT116077 WP_126100838.1 NZ_CP034448:c5759808-5759365 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
MTKLLGRPVVPSVDDAELAAQASRVLSRTKRDGAELKVQVGKETLRLPKSVGDLLYRLLTEMGQGNAVTVIPIHAELTTQ
EAADFLNVSRPYLIRLLEDGRLPFNMVGTHRRVKFSDLTAYRNSEEEERKKLMEELAAQAQELGMGY

Download         Length: 444 bp

>AT116077 NZ_CP034448:c5759808-5759365 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
ATGACCAAGCTGCTCGGACGACCGGTCGTGCCATCGGTGGACGATGCCGAACTCGCCGCTCAAGCCAGCCGGGTGCTTTC
ACGCACCAAGCGCGACGGTGCCGAATTGAAGGTTCAGGTGGGCAAGGAAACCTTGCGCCTGCCGAAGAGCGTTGGCGATC
TGCTTTACCGTCTCCTGACCGAAATGGGCCAGGGAAATGCGGTGACGGTGATCCCGATCCATGCCGAGCTTACGACACAG
GAGGCGGCGGACTTCCTCAACGTATCGCGCCCCTATCTCATCCGACTGCTGGAGGATGGCAGGTTGCCTTTCAACATGGT
CGGAACGCATCGGCGCGTGAAGTTTTCCGATTTGACGGCATACCGAAACAGCGAGGAGGAAGAGCGCAAAAAGCTCATGG
AAGAACTGGCCGCCCAAGCCCAGGAACTGGGGATGGGCTATTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References