Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PP_4151-4152/excise(antitoxin) |
| Location | 5758791..5759808 | Replicon | chromosome |
| Accession | NZ_CP034448 | ||
| Organism | Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1 | ||
Toxin (Protein)
| Gene name | PP_4152 | Uniprot ID | - |
| Locus tag | EJ071_RS28535 | Protein ID | WP_126100837.1 |
| Coordinates | 5758791..5759369 (-) | Length | 193 a.a. |
Antitoxin (Protein)
| Gene name | PP_4151 | Uniprot ID | - |
| Locus tag | EJ071_RS28540 | Protein ID | WP_126100838.1 |
| Coordinates | 5759365..5759808 (-) | Length | 148 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EJ071_RS28510 | 5754555..5754791 | + | 237 | WP_126100832.1 | DUF1127 domain-containing protein | - |
| EJ071_RS28515 | 5755056..5755649 | + | 594 | WP_126100833.1 | OsmC family protein | - |
| EJ071_RS28520 | 5755723..5756949 | + | 1227 | WP_126100834.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| EJ071_RS28525 | 5756967..5758280 | + | 1314 | WP_189521245.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| EJ071_RS28530 | 5758292..5758732 | + | 441 | WP_210211944.1 | MaoC family dehydratase N-terminal domain-containing protein | - |
| EJ071_RS28535 | 5758791..5759369 | - | 579 | WP_126100837.1 | PIN domain-containing protein | Toxin |
| EJ071_RS28540 | 5759365..5759808 | - | 444 | WP_126100838.1 | helix-turn-helix domain-containing protein | Antitoxin |
| EJ071_RS28545 | 5759946..5760662 | - | 717 | WP_126102757.1 | alpha/beta hydrolase | - |
| EJ071_RS28550 | 5761602..5763098 | - | 1497 | WP_126100839.1 | MFS transporter | - |
| EJ071_RS28555 | 5763233..5764159 | + | 927 | WP_126102758.1 | LysR family transcriptional regulator | - |
| EJ071_RS28560 | 5764333..5764629 | - | 297 | WP_126100840.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 193 a.a. Molecular weight: 21758.96 Da Isoelectric Point: 6.0980
>T116077 WP_126100837.1 NZ_CP034448:c5759369-5758791 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
IKTSSYTAVLDACVLYPAPLRDLLVELAAGGGLYRAKWTEQIHDEWIRNLLQNRPDLKPEQIYRTRDLMNRAVLDCLVDG
YQDLLPSLALPDENDRHVLAAAIVSAFDAIVTFNFRDFPKPVLDKYQLDLIHPDDFIFQQFGIDNAAVLVSVQRCRARLR
NPPRSAAEYLDTLERQGLPKTVGHLRAYAGVI
IKTSSYTAVLDACVLYPAPLRDLLVELAAGGGLYRAKWTEQIHDEWIRNLLQNRPDLKPEQIYRTRDLMNRAVLDCLVDG
YQDLLPSLALPDENDRHVLAAAIVSAFDAIVTFNFRDFPKPVLDKYQLDLIHPDDFIFQQFGIDNAAVLVSVQRCRARLR
NPPRSAAEYLDTLERQGLPKTVGHLRAYAGVI
Download Length: 579 bp
>T116077 NZ_CP034448:c5759369-5758791 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
ATTAAGACCTCTTCCTACACCGCCGTCCTGGACGCTTGCGTTCTTTATCCAGCCCCGCTGCGGGATCTTCTCGTCGAGCT
TGCCGCGGGAGGTGGCCTCTATCGGGCCAAATGGACAGAACAGATCCATGACGAGTGGATACGCAATCTCTTACAGAACC
GTCCGGATCTCAAGCCGGAGCAGATTTACAGAACACGCGACCTGATGAATCGCGCCGTCCTGGATTGTCTGGTTGACGGC
TATCAGGACTTGCTGCCGAGTCTGGCGCTTCCCGACGAAAATGACCGCCATGTTCTGGCTGCGGCCATCGTCTCGGCGTT
CGATGCGATCGTCACCTTCAATTTCAGGGATTTTCCCAAGCCCGTTCTCGATAAATACCAGTTGGACCTGATCCACCCCG
ACGATTTCATTTTCCAGCAGTTCGGCATCGACAATGCTGCCGTATTGGTCTCGGTTCAAAGATGTCGCGCACGTCTGAGG
AACCCTCCCAGGAGTGCCGCCGAGTACCTCGACACGCTGGAGAGGCAGGGCCTGCCCAAAACGGTTGGCCATCTGCGCGC
TTATGCTGGAGTGATCTAG
ATTAAGACCTCTTCCTACACCGCCGTCCTGGACGCTTGCGTTCTTTATCCAGCCCCGCTGCGGGATCTTCTCGTCGAGCT
TGCCGCGGGAGGTGGCCTCTATCGGGCCAAATGGACAGAACAGATCCATGACGAGTGGATACGCAATCTCTTACAGAACC
GTCCGGATCTCAAGCCGGAGCAGATTTACAGAACACGCGACCTGATGAATCGCGCCGTCCTGGATTGTCTGGTTGACGGC
TATCAGGACTTGCTGCCGAGTCTGGCGCTTCCCGACGAAAATGACCGCCATGTTCTGGCTGCGGCCATCGTCTCGGCGTT
CGATGCGATCGTCACCTTCAATTTCAGGGATTTTCCCAAGCCCGTTCTCGATAAATACCAGTTGGACCTGATCCACCCCG
ACGATTTCATTTTCCAGCAGTTCGGCATCGACAATGCTGCCGTATTGGTCTCGGTTCAAAGATGTCGCGCACGTCTGAGG
AACCCTCCCAGGAGTGCCGCCGAGTACCTCGACACGCTGGAGAGGCAGGGCCTGCCCAAAACGGTTGGCCATCTGCGCGC
TTATGCTGGAGTGATCTAG
Antitoxin
Download Length: 148 a.a. Molecular weight: 16438.91 Da Isoelectric Point: 7.2054
>AT116077 WP_126100838.1 NZ_CP034448:c5759808-5759365 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
MTKLLGRPVVPSVDDAELAAQASRVLSRTKRDGAELKVQVGKETLRLPKSVGDLLYRLLTEMGQGNAVTVIPIHAELTTQ
EAADFLNVSRPYLIRLLEDGRLPFNMVGTHRRVKFSDLTAYRNSEEEERKKLMEELAAQAQELGMGY
MTKLLGRPVVPSVDDAELAAQASRVLSRTKRDGAELKVQVGKETLRLPKSVGDLLYRLLTEMGQGNAVTVIPIHAELTTQ
EAADFLNVSRPYLIRLLEDGRLPFNMVGTHRRVKFSDLTAYRNSEEEERKKLMEELAAQAQELGMGY
Download Length: 444 bp
>AT116077 NZ_CP034448:c5759808-5759365 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
ATGACCAAGCTGCTCGGACGACCGGTCGTGCCATCGGTGGACGATGCCGAACTCGCCGCTCAAGCCAGCCGGGTGCTTTC
ACGCACCAAGCGCGACGGTGCCGAATTGAAGGTTCAGGTGGGCAAGGAAACCTTGCGCCTGCCGAAGAGCGTTGGCGATC
TGCTTTACCGTCTCCTGACCGAAATGGGCCAGGGAAATGCGGTGACGGTGATCCCGATCCATGCCGAGCTTACGACACAG
GAGGCGGCGGACTTCCTCAACGTATCGCGCCCCTATCTCATCCGACTGCTGGAGGATGGCAGGTTGCCTTTCAACATGGT
CGGAACGCATCGGCGCGTGAAGTTTTCCGATTTGACGGCATACCGAAACAGCGAGGAGGAAGAGCGCAAAAAGCTCATGG
AAGAACTGGCCGCCCAAGCCCAGGAACTGGGGATGGGCTATTAA
ATGACCAAGCTGCTCGGACGACCGGTCGTGCCATCGGTGGACGATGCCGAACTCGCCGCTCAAGCCAGCCGGGTGCTTTC
ACGCACCAAGCGCGACGGTGCCGAATTGAAGGTTCAGGTGGGCAAGGAAACCTTGCGCCTGCCGAAGAGCGTTGGCGATC
TGCTTTACCGTCTCCTGACCGAAATGGGCCAGGGAAATGCGGTGACGGTGATCCCGATCCATGCCGAGCTTACGACACAG
GAGGCGGCGGACTTCCTCAACGTATCGCGCCCCTATCTCATCCGACTGCTGGAGGATGGCAGGTTGCCTTTCAACATGGT
CGGAACGCATCGGCGCGTGAAGTTTTCCGATTTGACGGCATACCGAAACAGCGAGGAGGAAGAGCGCAAAAAGCTCATGG
AAGAACTGGCCGCCCAAGCCCAGGAACTGGGGATGGGCTATTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|