Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VagC |
| Location | 2708397..2709025 | Replicon | chromosome |
| Accession | NZ_CP034448 | ||
| Organism | Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | EJ071_RS13265 | Protein ID | WP_126098271.1 |
| Coordinates | 2708639..2709025 (+) | Length | 129 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | EJ071_RS13260 | Protein ID | WP_126098270.1 |
| Coordinates | 2708397..2708642 (+) | Length | 82 a.a. |
Genomic Context
Location: 2707235..2708317 (1083 bp)
Type: Others
Protein ID: WP_126098269.1
Type: Others
Protein ID: WP_126098269.1
Location: 2708397..2708642 (246 bp)
Type: Antitoxin
Protein ID: WP_126098270.1
Type: Antitoxin
Protein ID: WP_126098270.1
Location: 2708639..2709025 (387 bp)
Type: Toxin
Protein ID: WP_126098271.1
Type: Toxin
Protein ID: WP_126098271.1
Location: 2703480..2704232 (753 bp)
Type: Others
Protein ID: WP_126102564.1
Type: Others
Protein ID: WP_126102564.1
Location: 2704286..2705389 (1104 bp)
Type: Others
Protein ID: WP_126098265.1
Type: Others
Protein ID: WP_126098265.1
Location: 2705467..2705778 (312 bp)
Type: Others
Protein ID: WP_126098266.1
Type: Others
Protein ID: WP_126098266.1
Location: 2705830..2706612 (783 bp)
Type: Others
Protein ID: WP_189521540.1
Type: Others
Protein ID: WP_189521540.1
Location: 2706693..2707127 (435 bp)
Type: Others
Protein ID: WP_126098268.1
Type: Others
Protein ID: WP_126098268.1
Location: 2709028..2709975 (948 bp)
Type: Others
Protein ID: WP_126098272.1
Type: Others
Protein ID: WP_126098272.1
Location: 2709981..2712170 (2190 bp)
Type: Others
Protein ID: WP_126098273.1
Type: Others
Protein ID: WP_126098273.1
Location: 2712460..2713515 (1056 bp)
Type: Others
Protein ID: WP_126098274.1
Type: Others
Protein ID: WP_126098274.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EJ071_RS13230 | 2703480..2704232 | - | 753 | WP_126102564.1 | SDR family oxidoreductase | - |
| EJ071_RS13235 | 2704286..2705389 | - | 1104 | WP_126098265.1 | AbrB family transcriptional regulator | - |
| EJ071_RS13240 | 2705467..2705778 | - | 312 | WP_126098266.1 | antibiotic biosynthesis monooxygenase | - |
| EJ071_RS13245 | 2705830..2706612 | - | 783 | WP_189521540.1 | SDR family oxidoreductase | - |
| EJ071_RS13250 | 2706693..2707127 | - | 435 | WP_126098268.1 | DsrE family protein | - |
| EJ071_RS13255 | 2707235..2708317 | + | 1083 | WP_126098269.1 | hypothetical protein | - |
| EJ071_RS13260 | 2708397..2708642 | + | 246 | WP_126098270.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
| EJ071_RS13265 | 2708639..2709025 | + | 387 | WP_126098271.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| EJ071_RS13270 | 2709028..2709975 | - | 948 | WP_126098272.1 | cation diffusion facilitator family transporter | - |
| EJ071_RS13275 | 2709981..2712170 | - | 2190 | WP_126098273.1 | anthranilate synthase | - |
| EJ071_RS13280 | 2712460..2713515 | - | 1056 | WP_126098274.1 | succinylglutamate desuccinylase/aspartoacylase family protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 129 a.a. Molecular weight: 14382.64 Da Isoelectric Point: 6.4718
>T116076 WP_126098271.1 NZ_CP034448:2708639-2709025 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
VIYLLDTNAVIAIMKGDDDLLKVLKRNKPQDFALSAIVAHELYYGACRGQRTEENLARLDALLFPVLEFDREDARHAGEI
RAMLAVSGTPIGPFDVLIGGQARARSLTLMTRNVREFERIKNLAIETW
VIYLLDTNAVIAIMKGDDDLLKVLKRNKPQDFALSAIVAHELYYGACRGQRTEENLARLDALLFPVLEFDREDARHAGEI
RAMLAVSGTPIGPFDVLIGGQARARSLTLMTRNVREFERIKNLAIETW
Download Length: 387 bp
>T116076 NZ_CP034448:2708639-2709025 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
GTGATCTATCTGCTCGATACCAATGCTGTCATCGCCATCATGAAGGGCGATGATGATTTGCTGAAAGTGCTCAAGCGAAA
CAAGCCGCAAGATTTTGCGCTTTCGGCCATCGTTGCGCACGAGCTCTATTATGGGGCCTGCAGAGGCCAGCGAACGGAAG
AGAATCTCGCACGACTGGACGCCCTTCTGTTCCCGGTACTCGAATTCGATCGGGAAGACGCGCGGCACGCCGGCGAGATT
CGGGCGATGCTGGCGGTATCGGGAACTCCAATTGGTCCCTTTGATGTGCTTATTGGAGGCCAAGCACGTGCCCGCAGCCT
GACGTTGATGACACGAAATGTTCGCGAGTTCGAGCGGATTAAGAATCTGGCTATCGAGACCTGGTGA
GTGATCTATCTGCTCGATACCAATGCTGTCATCGCCATCATGAAGGGCGATGATGATTTGCTGAAAGTGCTCAAGCGAAA
CAAGCCGCAAGATTTTGCGCTTTCGGCCATCGTTGCGCACGAGCTCTATTATGGGGCCTGCAGAGGCCAGCGAACGGAAG
AGAATCTCGCACGACTGGACGCCCTTCTGTTCCCGGTACTCGAATTCGATCGGGAAGACGCGCGGCACGCCGGCGAGATT
CGGGCGATGCTGGCGGTATCGGGAACTCCAATTGGTCCCTTTGATGTGCTTATTGGAGGCCAAGCACGTGCCCGCAGCCT
GACGTTGATGACACGAAATGTTCGCGAGTTCGAGCGGATTAAGAATCTGGCTATCGAGACCTGGTGA
Antitoxin
Download Length: 82 a.a. Molecular weight: 9442.64 Da Isoelectric Point: 4.6558
>AT116076 WP_126098270.1 NZ_CP034448:2708397-2708642 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
MNKAKIFWSGRSQAVRLPKEFRFETDEVSIRRHGQTVVLEPLPQDWAWLDQVIGTLDDDFVDAAEERVEEQKRPALGDVF
K
MNKAKIFWSGRSQAVRLPKEFRFETDEVSIRRHGQTVVLEPLPQDWAWLDQVIGTLDDDFVDAAEERVEEQKRPALGDVF
K
Download Length: 246 bp
>AT116076 NZ_CP034448:2708397-2708642 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
ATGAACAAAGCAAAAATATTCTGGTCAGGCCGCTCGCAGGCCGTCCGCCTGCCGAAGGAGTTTCGCTTTGAAACTGACGA
GGTTTCGATCCGCCGTCATGGGCAGACTGTCGTTCTTGAACCTCTTCCGCAAGATTGGGCATGGCTCGATCAAGTGATCG
GGACACTTGACGACGATTTTGTCGATGCGGCGGAGGAAAGGGTAGAGGAGCAGAAACGGCCCGCTCTCGGCGACGTCTTC
AAGTGA
ATGAACAAAGCAAAAATATTCTGGTCAGGCCGCTCGCAGGCCGTCCGCCTGCCGAAGGAGTTTCGCTTTGAAACTGACGA
GGTTTCGATCCGCCGTCATGGGCAGACTGTCGTTCTTGAACCTCTTCCGCAAGATTGGGCATGGCTCGATCAAGTGATCG
GGACACTTGACGACGATTTTGTCGATGCGGCGGAGGAAAGGGTAGAGGAGCAGAAACGGCCCGCTCTCGGCGACGTCTTC
AAGTGA