Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TacT2-ataR/DUF1778(antitoxin)
Location 129737..130549 Replicon chromosome
Accession NZ_CP034448
Organism Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag EJ071_RS00585 Protein ID WP_126096334.1
Coordinates 129737..130246 (-) Length 170 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag EJ071_RS00590 Protein ID WP_126096335.1
Coordinates 130250..130549 (-) Length 100 a.a.

Genomic Context

EJ071_RS38310EJ071_RS00570EJ071_RS00575EJ071_RS00580EJ071_RS00585EJ071_RS00590EJ071_RS00595EJ071_RS00600EJ071_RS00605EJ071_RS00610
Location: 129516..129665 (150 bp)
Type: Others
Protein ID: WP_189521391.1
Location: 126207..126857 (651 bp)
Type: Others
Protein ID: WP_126102430.1
Location: 126890..128485 (1596 bp)
Type: Others
Protein ID: WP_126096332.1
Location: 128531..129163 (633 bp)
Type: Others
Protein ID: WP_126096333.1
Location: 129737..130246 (510 bp)
Type: Toxin
Protein ID: WP_126096334.1
Location: 130250..130549 (300 bp)
Type: Antitoxin
Protein ID: WP_126096335.1
Location: 130689..131390 (702 bp)
Type: Others
Protein ID: WP_126096336.1
Location: 131411..132718 (1308 bp)
Type: Others
Protein ID: WP_210211926.1
Location: 132858..133280 (423 bp)
Type: Others
Protein ID: WP_126086026.1
Location: 133421..135010 (1590 bp)
Type: Others
Protein ID: WP_126096338.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EJ071_RS00570126207..126857-651WP_126102430.1RNA-binding protein-
EJ071_RS00575126890..128485-1596WP_126096332.1transcription termination/antitermination protein NusA-
EJ071_RS00580128531..129163-633WP_126096333.1ribosome maturation factor RimP-
EJ071_RS38310129516..129665+150WP_189521391.1hypothetical protein-
EJ071_RS00585129737..130246-510WP_126096334.1GNAT family N-acetyltransferaseToxin
EJ071_RS00590130250..130549-300WP_126096335.1DUF1778 domain-containing proteinAntitoxin
EJ071_RS00595130689..131390-702WP_126096336.1tRNA (guanosine(46)-N(7))-methyltransferase TrmB-
EJ071_RS00600131411..132718-1308WP_210211926.1methionine adenosyltransferase-
EJ071_RS00605132858..133280-423WP_126086026.1helix-turn-helix transcriptional regulator-
EJ071_RS00610133421..135010-1590WP_126096338.1apolipoprotein N-acyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-143)

Antitoxin

Vibrio phage ICP1, Orf50

(3-92)


Sequences

Toxin        


Download         Length: 170 a.a.        Molecular weight: 17986.82 Da        Isoelectric Point: 9.2988

>T116075 WP_126096334.1 NZ_CP034448:c130246-129737 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
VALSAPEPLTAAHDVSGFSCGKPTLDHWLRTRALSNQEKGFTAVIVVHEASRVVGYYGLAPTAVVPSILPRSIRTGQPPD
PVPCLLLGQLATDTGWAGRGIGTGLVKHALQRCVQAAGLIGGRALMVNAIDEDAVQFWRRRGFLPTKDDPFVLFRPIATI
AASLVEAQK

Download         Length: 510 bp

>T116075 NZ_CP034448:c130246-129737 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
GTGGCCTTATCGGCTCCCGAACCGCTTACCGCAGCCCACGACGTTTCCGGATTTTCCTGCGGGAAACCGACACTTGATCA
CTGGCTGAGAACGCGCGCGCTCTCCAATCAGGAGAAGGGCTTTACGGCCGTTATCGTTGTCCATGAAGCCAGCCGCGTGG
TCGGATACTATGGTTTGGCGCCCACGGCCGTCGTGCCGTCGATCTTGCCCCGGTCGATCCGCACGGGGCAACCGCCGGAT
CCCGTGCCTTGTCTGCTCCTCGGCCAGCTTGCGACCGATACCGGATGGGCTGGGCGCGGCATCGGCACCGGCTTGGTGAA
ACATGCCCTTCAGCGCTGCGTCCAGGCAGCGGGACTGATTGGAGGGCGTGCGCTCATGGTCAATGCGATCGATGAGGACG
CTGTGCAATTCTGGCGGCGGCGGGGATTTCTCCCAACGAAGGACGATCCATTTGTCTTGTTTCGTCCGATCGCAACAATT
GCCGCATCGCTCGTGGAAGCCCAGAAGTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11019.71 Da        Isoelectric Point: 6.3716

>AT116075 WP_126096335.1 NZ_CP034448:c130549-130250 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
MAATVERKEYPISMRLPEADVAMIDRAATLRGRSRTDFVRDAAVRAAEDVLMNNRLVRMSPEGFAEFMEVLSAPAAPVPD
LVELAKRPAPWEAGYTTKR

Download         Length: 300 bp

>AT116075 NZ_CP034448:c130549-130250 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
ATGGCCGCCACGGTCGAACGTAAGGAATACCCGATCTCGATGCGCCTGCCGGAAGCGGACGTGGCGATGATTGACCGTGC
CGCCACTCTCCGCGGTCGGTCCCGTACGGACTTCGTGCGCGATGCCGCCGTACGCGCGGCCGAGGATGTGCTGATGAACA
ACCGCCTTGTCCGCATGAGCCCGGAAGGGTTCGCGGAATTTATGGAGGTCCTGTCGGCTCCGGCCGCCCCAGTCCCCGAT
TTGGTGGAATTGGCAAAGCGGCCCGCACCCTGGGAAGCTGGTTACACAACGAAGCGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References