Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TacT2-ataR/DUF1778(antitoxin)
Location 129737..130549 Replicon chromosome
Accession NZ_CP034448
Organism Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag EJ071_RS00585 Protein ID WP_126096334.1
Coordinates 129737..130246 (-) Length 170 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag EJ071_RS00590 Protein ID WP_126096335.1
Coordinates 130250..130549 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJ071_RS00570 126207..126857 - 651 WP_126102430.1 RNA-binding protein -
EJ071_RS00575 126890..128485 - 1596 WP_126096332.1 transcription termination/antitermination protein NusA -
EJ071_RS00580 128531..129163 - 633 WP_126096333.1 ribosome maturation factor RimP -
EJ071_RS38310 129516..129665 + 150 WP_189521391.1 hypothetical protein -
EJ071_RS00585 129737..130246 - 510 WP_126096334.1 GNAT family N-acetyltransferase Toxin
EJ071_RS00590 130250..130549 - 300 WP_126096335.1 DUF1778 domain-containing protein Antitoxin
EJ071_RS00595 130689..131390 - 702 WP_126096336.1 tRNA (guanosine(46)-N(7))-methyltransferase TrmB -
EJ071_RS00600 131411..132718 - 1308 WP_210211926.1 methionine adenosyltransferase -
EJ071_RS00605 132858..133280 - 423 WP_126086026.1 helix-turn-helix transcriptional regulator -
EJ071_RS00610 133421..135010 - 1590 WP_126096338.1 apolipoprotein N-acyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-143)

Antitoxin

Vibrio phage ICP1, Orf50

(3-92)


Sequences

Toxin        


Download         Length: 170 a.a.        Molecular weight: 17986.82 Da        Isoelectric Point: 9.2988

>T116075 WP_126096334.1 NZ_CP034448:c130246-129737 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
VALSAPEPLTAAHDVSGFSCGKPTLDHWLRTRALSNQEKGFTAVIVVHEASRVVGYYGLAPTAVVPSILPRSIRTGQPPD
PVPCLLLGQLATDTGWAGRGIGTGLVKHALQRCVQAAGLIGGRALMVNAIDEDAVQFWRRRGFLPTKDDPFVLFRPIATI
AASLVEAQK

Download         Length: 510 bp

>T116075 NZ_CP034448:c130246-129737 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
GTGGCCTTATCGGCTCCCGAACCGCTTACCGCAGCCCACGACGTTTCCGGATTTTCCTGCGGGAAACCGACACTTGATCA
CTGGCTGAGAACGCGCGCGCTCTCCAATCAGGAGAAGGGCTTTACGGCCGTTATCGTTGTCCATGAAGCCAGCCGCGTGG
TCGGATACTATGGTTTGGCGCCCACGGCCGTCGTGCCGTCGATCTTGCCCCGGTCGATCCGCACGGGGCAACCGCCGGAT
CCCGTGCCTTGTCTGCTCCTCGGCCAGCTTGCGACCGATACCGGATGGGCTGGGCGCGGCATCGGCACCGGCTTGGTGAA
ACATGCCCTTCAGCGCTGCGTCCAGGCAGCGGGACTGATTGGAGGGCGTGCGCTCATGGTCAATGCGATCGATGAGGACG
CTGTGCAATTCTGGCGGCGGCGGGGATTTCTCCCAACGAAGGACGATCCATTTGTCTTGTTTCGTCCGATCGCAACAATT
GCCGCATCGCTCGTGGAAGCCCAGAAGTAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11019.71 Da        Isoelectric Point: 6.3716

>AT116075 WP_126096335.1 NZ_CP034448:c130549-130250 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
MAATVERKEYPISMRLPEADVAMIDRAATLRGRSRTDFVRDAAVRAAEDVLMNNRLVRMSPEGFAEFMEVLSAPAAPVPD
LVELAKRPAPWEAGYTTKR

Download         Length: 300 bp

>AT116075 NZ_CP034448:c130549-130250 [Mesorhizobium sp. M1B.F.Ca.ET.045.04.1.1]
ATGGCCGCCACGGTCGAACGTAAGGAATACCCGATCTCGATGCGCCTGCCGGAAGCGGACGTGGCGATGATTGACCGTGC
CGCCACTCTCCGCGGTCGGTCCCGTACGGACTTCGTGCGCGATGCCGCCGTACGCGCGGCCGAGGATGTGCTGATGAACA
ACCGCCTTGTCCGCATGAGCCCGGAAGGGTTCGCGGAATTTATGGAGGTCCTGTCGGCTCCGGCCGCCCCAGTCCCCGAT
TTGGTGGAATTGGCAAAGCGGCCCGCACCCTGGGAAGCTGGTTACACAACGAAGCGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References