Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 6681369..6682135 Replicon chromosome
Accession NZ_CP034447
Organism Mesorhizobium sp. M1E.F.Ca.ET.045.02.1.1

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag EJ070_RS32735 Protein ID WP_126095037.1
Coordinates 6681650..6682135 (+) Length 162 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag EJ070_RS32730 Protein ID WP_126095036.1
Coordinates 6681369..6681650 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJ070_RS32705 6676526..6678649 + 2124 WP_126095031.1 methylmalonyl-CoA mutase -
EJ070_RS32710 6678721..6678942 + 222 WP_126095032.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
EJ070_RS32715 6678939..6679328 + 390 WP_126095033.1 type II toxin-antitoxin system death-on-curing family toxin -
EJ070_RS32720 6679325..6679807 - 483 WP_126095034.1 transcription elongation factor GreA -
EJ070_RS32725 6679914..6681290 + 1377 WP_126095035.1 TIGR03808 family TAT-translocated repetitive protein -
EJ070_RS32730 6681369..6681650 + 282 WP_126095036.1 DUF1778 domain-containing protein Antitoxin
EJ070_RS32735 6681650..6682135 + 486 WP_126095037.1 GNAT family N-acetyltransferase Toxin
EJ070_RS32740 6682192..6683196 - 1005 WP_126095038.1 asparaginase -
EJ070_RS32745 6683227..6684393 - 1167 WP_126095039.1 acetyl-CoA acetyltransferase -
EJ070_RS32750 6684581..6685171 + 591 WP_126095040.1 transcriptional regulator BetI -
EJ070_RS32755 6685168..6686697 + 1530 WP_126095041.1 choline-sulfatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-142)

Antitoxin

Vibrio phage ICP1, Orf50

(4-79)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17268.93 Da        Isoelectric Point: 10.2339

>T116074 WP_126095037.1 NZ_CP034447:6681650-6682135 [Mesorhizobium sp. M1E.F.Ca.ET.045.02.1.1]
MLSAPALLADSHELDLFQSRNDSLDQWLRRRARANQVIGASRTYVIAETTRVVGYYCLSSGGLDLAGTPGSIRRNMPDPV
PVAVLGRLAVDASWQGKGLGGALLQDAVLRTGQAAAILGIRGLLVHAISDGAKAFYEHYGFQAPPKNPMTLVLSLKMAQK
R

Download         Length: 486 bp

>T116074 NZ_CP034447:6681650-6682135 [Mesorhizobium sp. M1E.F.Ca.ET.045.02.1.1]
ATGCTATCGGCACCAGCCCTTCTTGCCGATAGTCACGAACTCGACCTTTTCCAAAGCAGGAACGACAGCCTGGATCAATG
GCTTCGACGGCGGGCGCGCGCCAATCAAGTCATCGGGGCGTCCAGAACCTATGTGATTGCAGAAACCACACGTGTTGTCG
GTTATTATTGCCTTTCATCAGGTGGACTTGACCTGGCGGGTACACCCGGTTCGATCCGGCGCAATATGCCCGATCCGGTG
CCCGTGGCTGTACTTGGCCGTTTGGCTGTCGATGCAAGCTGGCAGGGAAAAGGTCTGGGCGGCGCCCTGTTGCAGGACGC
GGTGCTGCGGACCGGTCAAGCGGCAGCCATCCTCGGCATTCGCGGTCTCTTGGTTCATGCCATATCGGATGGAGCCAAAG
CGTTTTATGAGCACTATGGCTTCCAGGCTCCCCCGAAAAATCCGATGACTTTGGTGCTGTCGCTGAAGATGGCTCAGAAG
AGGTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10652.13 Da        Isoelectric Point: 8.5141

>AT116074 WP_126095036.1 NZ_CP034447:6681369-6681650 [Mesorhizobium sp. M1E.F.Ca.ET.045.02.1.1]
MAAKNQDTHAKPVNLRIREDVRILIDRAAKIRGKTRSDFMIDAAYRAAEDTLLDQTLVKVDAESYQHYLDILDRPPSGEG
FARLMNAPKPWRD

Download         Length: 282 bp

>AT116074 NZ_CP034447:6681369-6681650 [Mesorhizobium sp. M1E.F.Ca.ET.045.02.1.1]
ATGGCCGCGAAAAACCAGGACACCCACGCCAAGCCCGTCAATCTGCGCATCCGTGAGGATGTCCGCATCCTGATCGACCG
CGCCGCGAAGATACGCGGGAAGACTCGCTCCGACTTCATGATCGACGCCGCTTACCGTGCGGCCGAAGACACGCTGCTCG
ACCAGACGCTCGTCAAGGTCGATGCCGAAAGCTATCAGCATTATCTCGATATCCTCGATCGGCCTCCGAGCGGCGAGGGA
TTTGCCCGCCTGATGAATGCGCCGAAGCCTTGGCGGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References