Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 4216669..4217481 Replicon chromosome
Accession NZ_CP034446
Organism Mesorhizobium sp. M2A.F.Ca.ET.043.05.1.1

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag EJ069_RS20475 Protein ID WP_126062847.1
Coordinates 4216669..4217178 (-) Length 170 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag EJ069_RS20480 Protein ID WP_126062848.1
Coordinates 4217182..4217481 (-) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJ069_RS20460 4213563..4214213 - 651 WP_126064824.1 RNA-binding protein -
EJ069_RS20465 4214246..4215841 - 1596 WP_126062845.1 transcription termination/antitermination protein NusA -
EJ069_RS20470 4215888..4216514 - 627 WP_126062846.1 ribosome maturation factor RimP -
EJ069_RS20475 4216669..4217178 - 510 WP_126062847.1 GNAT family N-acetyltransferase Toxin
EJ069_RS20480 4217182..4217481 - 300 WP_126062848.1 DUF1778 domain-containing protein Antitoxin
EJ069_RS20485 4217546..4218256 - 711 WP_126062849.1 tRNA (guanosine(46)-N(7))-methyltransferase TrmB -
EJ069_RS20490 4218253..4219557 - 1305 WP_210211348.1 methionine adenosyltransferase -
EJ069_RS20495 4219685..4220107 - 423 WP_095819313.1 helix-turn-helix transcriptional regulator -
EJ069_RS20500 4220247..4221833 - 1587 WP_126062851.1 apolipoprotein N-acyltransferase -
EJ069_RS20505 4221931..4222401 - 471 WP_126062852.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(39-143)

Antitoxin

Vibrio phage ICP1, Orf50

(3-92)


Sequences

Toxin        


Download         Length: 170 a.a.        Molecular weight: 17947.74 Da        Isoelectric Point: 8.7616

>T116070 WP_126062847.1 NZ_CP034446:c4217178-4216669 [Mesorhizobium sp. M2A.F.Ca.ET.043.05.1.1]
VALSAPESLTAIHDVSGFSCGKPALDHWLKSRALSNQEKGFTAVLVVHEAGRVVGYYGLAPTAVVPSILRRSIRTGQPPD
PVPCLLLGQLATDVEWAGRGIGTGLVKHALQRCVQAADLIGGRALMVNAVDAEAAQFWQRRGFLPTKDDSLILFRSIAAI
AASLVEAQR

Download         Length: 510 bp

>T116070 NZ_CP034446:c4217178-4216669 [Mesorhizobium sp. M2A.F.Ca.ET.043.05.1.1]
GTGGCCTTATCGGCTCCCGAGTCGCTTACCGCAATTCACGACGTGTCTGGATTTTCCTGTGGGAAGCCTGCGCTTGATCA
CTGGCTGAAAAGCCGTGCGCTCTCCAATCAGGAGAAGGGTTTCACGGCCGTTCTGGTTGTCCACGAAGCCGGCCGAGTGG
TCGGATATTATGGGTTGGCGCCGACGGCCGTCGTGCCGTCGATCCTGCGTCGGTCGATCCGTACGGGGCAACCGCCCGAT
CCGGTGCCGTGCCTCCTTCTCGGCCAGCTTGCGACCGACGTCGAATGGGCCGGGCGCGGCATCGGCACGGGCTTGGTGAA
GCATGCCCTTCAGCGTTGTGTTCAAGCGGCGGACCTGATCGGCGGGCGCGCGCTGATGGTAAATGCAGTCGATGCGGAAG
CGGCGCAATTCTGGCAACGGCGGGGATTTCTCCCGACGAAGGACGATTCGCTTATCCTGTTTCGTTCGATCGCGGCAATC
GCCGCGTCGCTCGTGGAGGCCCAAAGATAA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 11054.73 Da        Isoelectric Point: 5.2072

>AT116070 WP_126062848.1 NZ_CP034446:c4217481-4217182 [Mesorhizobium sp. M2A.F.Ca.ET.043.05.1.1]
MTATVERKEYPISMRLPEADVAMIDRAASLRGRSRTDFVRDAAVRAAEDVLMDNRLVRMSPEGFAEFMEVLSVPAAPVPD
MAELAKRPAPWEAGYTTKR

Download         Length: 300 bp

>AT116070 NZ_CP034446:c4217481-4217182 [Mesorhizobium sp. M2A.F.Ca.ET.043.05.1.1]
ATGACGGCCACGGTCGAACGCAAGGAATATCCGATCTCGATGCGCCTGCCGGAAGCGGACGTGGCGATGATCGATCGCGC
CGCCAGTCTGCGGGGCCGGTCGCGCACGGATTTCGTGCGCGATGCCGCCGTGCGCGCGGCCGAGGATGTGCTGATGGACA
ACCGTCTTGTCCGCATGAGCCCGGAAGGATTCGCGGAGTTCATGGAGGTCCTGTCAGTTCCGGCTGCTCCGGTTCCCGAC
ATGGCGGAACTGGCAAAGCGGCCCGCTCCGTGGGAAGCCGGTTACACGACGAAGCGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References