Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 2883794..2884449 Replicon chromosome
Accession NZ_CP034445
Organism Mesorhizobium sp. M2A.F.Ca.ET.043.02.1.1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EJ068_RS13580 Protein ID WP_126080570.1
Coordinates 2884048..2884449 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EJ068_RS13575 Protein ID WP_126080571.1
Coordinates 2883794..2884048 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJ068_RS13560 2879635..2880216 - 582 WP_127249873.1 hypothetical protein -
EJ068_RS13565 2880203..2882830 - 2628 WP_126080573.1 leucine--tRNA ligase -
EJ068_RS13570 2883047..2883709 + 663 WP_126080572.1 YggS family pyridoxal phosphate-dependent enzyme -
EJ068_RS13575 2883794..2884048 + 255 WP_126080571.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EJ068_RS13580 2884048..2884449 + 402 WP_126080570.1 type II toxin-antitoxin system VapC family toxin Toxin
EJ068_RS13585 2884579..2885628 + 1050 WP_126080569.1 aldo/keto reductase -
EJ068_RS13590 2885690..2886595 - 906 WP_127249870.1 LysR family transcriptional regulator -
EJ068_RS13595 2886717..2887904 + 1188 WP_126080567.1 MFS transporter -
EJ068_RS13600 2887942..2888976 + 1035 WP_127249869.1 aldo/keto reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-116)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-61)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14794.05 Da        Isoelectric Point: 5.9036

>T116063 WP_126080570.1 NZ_CP034445:2884048-2884449 [Mesorhizobium sp. M2A.F.Ca.ET.043.02.1.1]
MYLLDTNVVSDVQRRLPKPTAWIASIDPASINLSVITLGEIERGIVKQRKIDPERAARLDIWLRELRRDNTDRILAITEE
VALAWGRITAGRTRGSADSLIAATALVHDLILVTRNVADFEGVGVTVLNPWEV

Download         Length: 402 bp

>T116063 NZ_CP034445:2884048-2884449 [Mesorhizobium sp. M2A.F.Ca.ET.043.02.1.1]
ATGTATCTGCTGGACACGAACGTCGTGTCGGACGTGCAAAGACGGTTGCCTAAGCCGACTGCCTGGATAGCTTCGATTGA
TCCGGCGTCGATCAACCTTAGTGTCATTACGCTGGGTGAGATCGAGCGAGGAATCGTCAAACAGCGTAAGATCGACCCTG
AAAGGGCGGCTCGGCTCGATATCTGGCTGCGAGAACTTCGAAGAGACAATACGGACCGCATTCTCGCGATCACGGAGGAG
GTCGCTCTTGCCTGGGGTCGCATAACGGCGGGACGCACACGGGGGAGCGCCGACTCGCTTATTGCGGCGACCGCCCTCGT
GCACGACCTGATCCTGGTCACGCGAAACGTCGCCGACTTCGAGGGCGTCGGCGTTACAGTCCTCAATCCCTGGGAAGTCT
GA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9634.81 Da        Isoelectric Point: 5.8561

>AT116063 WP_126080571.1 NZ_CP034445:2883794-2884048 [Mesorhizobium sp. M2A.F.Ca.ET.043.02.1.1]
MNWHLQDAKNNFSKVVQRARTEGPQTVTLRGERAAVVLSADDYDRLAGKKKSLVEYLLSGPGWDEEFDKEITRRSDTIIR
DIDL

Download         Length: 255 bp

>AT116063 NZ_CP034445:2883794-2884048 [Mesorhizobium sp. M2A.F.Ca.ET.043.02.1.1]
ATGAACTGGCATCTTCAGGACGCGAAGAACAATTTCTCGAAAGTGGTCCAGCGGGCGCGAACCGAGGGACCGCAGACCGT
GACACTTCGCGGCGAACGTGCCGCGGTCGTCCTCTCCGCAGACGACTACGATCGCTTGGCCGGGAAGAAGAAATCGCTCG
TCGAGTACCTATTGAGCGGTCCAGGTTGGGACGAGGAGTTTGACAAGGAAATCACCCGTCGCTCGGACACGATTATCCGG
GACATTGATCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References