Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 6966526..6967340 Replicon chromosome
Accession NZ_CP034444
Organism Mesorhizobium sp. M1D.F.Ca.ET.043.01.1.1

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag EJ067_RS33630 Protein ID WP_126089341.1
Coordinates 6966801..6967340 (+) Length 180 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag EJ067_RS33625 Protein ID WP_125005424.1
Coordinates 6966526..6966804 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJ067_RS33600 6962448..6963662 - 1215 WP_126089337.1 plasmid partitioning protein RepA -
EJ067_RS33615 6964674..6964883 - 210 WP_126089339.1 hypothetical protein -
EJ067_RS33620 6965171..6966301 - 1131 WP_126089340.1 site-specific integrase -
EJ067_RS33625 6966526..6966804 + 279 WP_125005424.1 DUF1778 domain-containing protein Antitoxin
EJ067_RS33630 6966801..6967340 + 540 WP_126089341.1 GNAT family N-acetyltransferase Toxin
EJ067_RS33635 6967503..6969122 + 1620 Protein_6598 Mu transposase C-terminal domain-containing protein -
EJ067_RS33640 6969119..6970036 + 918 WP_210211678.1 TniB family NTP-binding protein -
EJ067_RS33645 6970048..6971166 + 1119 WP_189510250.1 TniQ family protein -
EJ067_RS33650 6971099..6972037 - 939 WP_126089344.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(39-147)

Antitoxin

Vibrio phage ICP1, Orf50

(5-88)


Sequences

Toxin        


Download         Length: 180 a.a.        Molecular weight: 19304.98 Da        Isoelectric Point: 8.3178

>T116062 WP_126089341.1 NZ_CP034444:6966801-6967340 [Mesorhizobium sp. M1D.F.Ca.ET.043.01.1.1]
MNLPAWHEEPISKAHDRSDFDCGDADMNDFLARFARQGHEQNATKTYCAIETARPGRILGFYSIAPSAVDHAAVPARMTK
GLARHDVPGFLLARIATDRSIAGQGLGGQLLAAAARRCLRLVTEGGGILLIIDAKNQRAADWYASFGAEALQGHRQAQPL
RLVIHLATFAADLRAAGHL

Download         Length: 540 bp

>T116062 NZ_CP034444:6966801-6967340 [Mesorhizobium sp. M1D.F.Ca.ET.043.01.1.1]
ATGAACCTTCCGGCCTGGCACGAGGAGCCGATCTCGAAGGCGCATGATCGGAGCGACTTCGATTGCGGTGACGCCGACAT
GAACGACTTCCTGGCCCGTTTTGCGCGCCAGGGCCATGAACAGAACGCCACCAAGACGTATTGCGCGATAGAAACCGCGC
GGCCCGGTCGGATCCTTGGATTCTATTCGATCGCGCCGTCGGCAGTCGATCATGCAGCCGTGCCAGCGCGCATGACCAAG
GGGCTCGCGCGTCACGATGTCCCGGGCTTTCTGTTGGCGCGGATCGCCACCGACAGATCGATCGCAGGGCAGGGGCTGGG
CGGTCAGCTGCTGGCTGCCGCCGCTAGGCGGTGTCTGCGGCTGGTGACGGAGGGCGGCGGCATCCTTTTGATCATCGACG
CCAAGAACCAACGCGCGGCTGATTGGTACGCCTCCTTCGGCGCCGAGGCCCTGCAGGGCCACCGCCAAGCTCAGCCGCTT
CGACTGGTGATCCATCTGGCAACATTCGCGGCGGATTTGCGGGCCGCTGGCCATCTCTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10282.93 Da        Isoelectric Point: 8.9115

>AT116062 WP_125005424.1 NZ_CP034444:6966526-6966804 [Mesorhizobium sp. M1D.F.Ca.ET.043.01.1.1]
MPRAAIEANERMNLRVAAQQKATLMRAAALVHADLTEFVTRAALREAEAVIKSAERIEVSERDFLRILELLDNPPPPNEK
LRAAIAALPRDR

Download         Length: 279 bp

>AT116062 NZ_CP034444:6966526-6966804 [Mesorhizobium sp. M1D.F.Ca.ET.043.01.1.1]
ATGCCTCGGGCAGCGATTGAAGCGAATGAACGGATGAACCTGCGGGTGGCGGCGCAACAGAAGGCGACGCTGATGCGGGC
AGCCGCGCTGGTGCATGCGGATTTGACGGAGTTCGTCACCCGTGCGGCCCTGCGCGAGGCCGAAGCGGTAATCAAGAGCG
CCGAGAGGATAGAGGTCTCGGAACGGGATTTCCTGCGCATTCTGGAGCTTTTGGACAACCCGCCGCCGCCTAACGAAAAA
CTGCGCGCCGCGATCGCCGCCTTGCCGCGTGATCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References