Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 4580463..4581993 Replicon chromosome
Accession NZ_CP034444
Organism Mesorhizobium sp. M1D.F.Ca.ET.043.01.1.1

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag EJ067_RS22140 Protein ID WP_126087363.1
Coordinates 4581079..4581993 (+) Length 305 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag EJ067_RS22135 Protein ID WP_126087362.1
Coordinates 4580463..4581089 (+) Length 209 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJ067_RS22120 4576538..4578706 + 2169 WP_126087360.1 ParB/RepB/Spo0J family partition protein -
EJ067_RS22125 4578941..4579225 - 285 WP_126087361.1 HU family DNA-binding protein -
EJ067_RS22130 4579287..4580117 - 831 Protein_4340 hypothetical protein -
EJ067_RS22135 4580463..4581089 + 627 WP_126087362.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
EJ067_RS22140 4581079..4581993 + 915 WP_126087363.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
EJ067_RS22150 4582760..4583923 - 1164 WP_126087364.1 amidohydrolase -
EJ067_RS22155 4584134..4585300 + 1167 WP_126087365.1 D-alanyl-D-alanine carboxypeptidase -
EJ067_RS22160 4585315..4586421 + 1107 WP_126089704.1 GTP-binding protein -
EJ067_RS22165 4586437..4586673 - 237 WP_126087366.1 sulfurtransferase TusA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-260)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(14-56)


Sequences

Toxin        


Download         Length: 305 a.a.        Molecular weight: 33975.97 Da        Isoelectric Point: 5.8442

>T116061 WP_126087363.1 NZ_CP034444:4581079-4581993 [Mesorhizobium sp. M1D.F.Ca.ET.043.01.1.1]
MRDRPANFPASVFARLRNIARHKQTDNQLILRRYAIERLLYRLSISPHRDQFILKGAMLFTAWLDDPFRPTQDLDLLGFG
NPAVTAIRAVFETICRIEAEDDGLVFDADGLSVEPIREDLQYGGVRVKTTAFLGRTRIPVQVDIGFGDAVTPAVQELEFP
SLLSAERPLLRAYPRETVVAEKLQAIVALGQANSRMKDFYDLLALSRLFAFEGRSLTPAIRATFARRDTPLPTDTPLGLS
IAFAEDGEKARQWSAFVGREPLLLRPSDFPATIISIAEFLLPPLEAEASGHSFERLWPAGGPWT

Download         Length: 915 bp

>T116061 NZ_CP034444:4581079-4581993 [Mesorhizobium sp. M1D.F.Ca.ET.043.01.1.1]
ATGAGGGATAGGCCGGCAAATTTTCCAGCATCGGTTTTTGCCCGGCTCCGCAACATCGCGCGACACAAGCAGACGGACAA
TCAGCTCATTCTGAGGCGATACGCCATCGAGAGGCTGCTTTATCGGTTGAGCATCTCCCCGCATCGCGATCAGTTCATCC
TGAAGGGTGCGATGCTCTTCACAGCGTGGCTCGACGATCCGTTTCGCCCCACGCAGGATCTCGATCTTCTCGGATTTGGC
AATCCCGCCGTAACGGCGATCCGCGCCGTTTTCGAAACGATCTGCCGGATCGAGGCCGAAGATGACGGACTGGTGTTCGA
CGCCGATGGCCTCAGCGTCGAGCCGATCCGTGAAGACCTGCAATATGGCGGCGTCAGGGTGAAGACGACGGCGTTTCTCG
GGAGGACCCGAATCCCGGTGCAGGTCGACATTGGCTTTGGCGATGCCGTTACGCCGGCGGTGCAAGAACTGGAATTTCCA
TCGCTTCTGTCCGCCGAACGTCCCTTGCTGAGAGCCTATCCCAGAGAGACCGTAGTTGCAGAGAAGCTTCAGGCGATTGT
CGCGCTTGGCCAGGCGAATAGCCGCATGAAGGATTTTTACGATCTGCTGGCGCTATCGCGCCTGTTCGCGTTCGAGGGCC
GATCGCTGACGCCGGCAATTCGGGCAACATTTGCACGCCGTGACACGCCACTGCCCACCGACACACCGCTTGGCTTGAGC
ATTGCTTTTGCCGAGGACGGCGAGAAGGCAAGGCAATGGTCGGCGTTCGTCGGAAGGGAACCGCTGCTTTTGCGGCCGTC
GGATTTCCCCGCTACGATCATCAGCATTGCGGAATTCCTTCTTCCGCCGCTCGAGGCGGAGGCCTCCGGCCACAGTTTCG
AGCGCCTCTGGCCGGCGGGCGGACCGTGGACATAA

Antitoxin


Download         Length: 209 a.a.        Molecular weight: 23355.04 Da        Isoelectric Point: 10.0941

>AT116061 WP_126087362.1 NZ_CP034444:4580463-4581089 [Mesorhizobium sp. M1D.F.Ca.ET.043.01.1.1]
MTESVETSQRNLAVSLIERHGIMRLSDLKRRGINPATLARLVDEGILHRSSRGLYERADADVDISHSLAEVATRVPKGVI
CLVSALQFHEITLQLPRSVWIAIGSKDRKPTIDYPPIRIARFSEKALTLGVKTYTIDSVSVRIFDPAKSIVDCFRFRNVV
GLDVAMEALRMGWRSRKAKPDEIARYAQALRIWSVVRPYLESAVADEG

Download         Length: 627 bp

>AT116061 NZ_CP034444:4580463-4581089 [Mesorhizobium sp. M1D.F.Ca.ET.043.01.1.1]
ATGACTGAATCCGTTGAAACCTCTCAACGCAACCTTGCGGTCAGTCTGATTGAGCGCCATGGGATCATGCGCCTGTCGGA
TCTGAAACGCCGAGGGATCAATCCGGCTACACTGGCGCGTCTGGTTGACGAGGGCATCCTCCATCGCTCCTCACGTGGGC
TCTATGAACGCGCGGATGCCGACGTTGACATTTCTCATTCCCTGGCCGAGGTCGCGACCCGTGTTCCGAAAGGTGTGATC
TGCCTCGTATCGGCGCTCCAGTTTCACGAGATTACGCTGCAGCTGCCGCGCAGCGTCTGGATCGCAATCGGCTCCAAGGA
CCGTAAGCCGACGATCGACTACCCGCCAATTCGTATTGCCCGCTTCAGCGAAAAGGCGCTCACCCTTGGCGTCAAGACCT
ACACCATTGACTCGGTGTCTGTCCGGATATTCGATCCGGCCAAGTCGATTGTCGACTGCTTCCGCTTCCGCAACGTCGTC
GGCCTCGACGTTGCAATGGAAGCGCTGCGCATGGGCTGGCGATCCAGAAAGGCCAAACCCGACGAAATTGCCCGGTATGC
CCAGGCGCTGCGCATCTGGAGCGTCGTTCGGCCCTATCTCGAAAGCGCAGTTGCCGATGAGGGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References