Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-VagC
Location 5615932..5616602 Replicon chromosome
Accession NZ_CP034443
Organism Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EJ066_RS27170 Protein ID WP_126043011.1
Coordinates 5615932..5616330 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EJ066_RS27175 Protein ID WP_126043012.1
Coordinates 5616330..5616602 (-) Length 91 a.a.

Genomic Context


EJ066_RS27150EJ066_RS27155EJ066_RS27160EJ066_RS27165EJ066_RS27180EJ066_RS27185EJ066_RS27170EJ066_RS27175EJ066_RS27190EJ066_RS27195EJ066_RS27200
Location: 5612073..5613101 (1029 bp)
Type: Others
Protein ID: WP_126043007.1
Location: 5613134..5613985 (852 bp)
Type: Others
Protein ID: WP_126043008.1
Location: 5613978..5614862 (885 bp)
Type: Others
Protein ID: WP_126043009.1
Location: 5614875..5615915 (1041 bp)
Type: Others
Protein ID: WP_126043010.1
Location: 5616837..5617823 (987 bp)
Type: Others
Protein ID: WP_126043013.1
Location: 5618075..5618524 (450 bp)
Type: Others
Protein ID: WP_126043014.1
Location: 5615932..5616330 (399 bp)
Type: Toxin
Protein ID: WP_126043011.1
Location: 5616330..5616602 (273 bp)
Type: Antitoxin
Protein ID: WP_126043012.1
Location: 5618521..5619006 (486 bp)
Type: Others
Protein ID: WP_126044064.1
Location: 5619078..5620064 (987 bp)
Type: Others
Protein ID: WP_126043015.1
Location: 5620061..5621041 (981 bp)
Type: Others
Protein ID: WP_126043016.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EJ066_RS271505612073..5613101+1029WP_126043007.1sulfate ABC transporter substrate-binding protein-
EJ066_RS271555613134..5613985+852WP_126043008.1sulfate ABC transporter permease subunit CysT-
EJ066_RS271605613978..5614862+885WP_126043009.1sulfate ABC transporter permease subunit CysW-
EJ066_RS271655614875..5615915+1041WP_126043010.1sulfate/molybdate ABC transporter ATP-binding protein-
EJ066_RS271705615932..5616330-399WP_126043011.1type II toxin-antitoxin system VapC family toxinToxin
EJ066_RS271755616330..5616602-273WP_126043012.1antitoxinAntitoxin
EJ066_RS271805616837..5617823+987WP_126043013.1sulfate ABC transporter substrate-binding protein-
EJ066_RS271855618075..5618524+450WP_126043014.1Rrf2 family transcriptional regulator-
EJ066_RS271905618521..5619006-486WP_126044064.1gluconokinase-
EJ066_RS271955619078..5620064-987WP_126043015.1ABC transporter permease-
EJ066_RS272005620061..5621041-981WP_126043016.1ABC transporter permease-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(4-123)

Antitoxin

(17-54)


Sequences


Toxin        


Download         Length: 133 a.a.        Molecular weight: 14126.42 Da        Isoelectric Point: 5.7385

>T116058 WP_126043011.1 NZ_CP034443:c5616330-5615932 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
MRFMLDTNIISDMIRNPAGKAASAMVREGDAAVCTSIVVASELRYGCARKGSAKLLKKVEELLAEIPVLPLDVPVDTEYG
ALRTELEGAGQTIGHNDLFIAAHACALGITLVTANTGEFNRIKGLKIENWLA

Download         Length: 399 bp

>T116058 NZ_CP034443:c5616330-5615932 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
ATGCGGTTCATGCTGGACACGAACATTATCAGCGACATGATCCGAAACCCGGCTGGCAAAGCAGCAAGTGCAATGGTGCG
CGAGGGAGACGCCGCCGTGTGCACCAGCATCGTGGTCGCCTCGGAACTGCGATATGGCTGCGCCAGGAAGGGATCGGCCA
AGCTGCTTAAGAAAGTCGAGGAGCTGCTGGCTGAGATCCCTGTTTTGCCGCTCGATGTGCCGGTAGATACCGAGTACGGC
GCACTTCGCACCGAGCTGGAAGGCGCGGGCCAGACCATTGGCCACAATGACCTTTTTATTGCTGCCCACGCCTGCGCACT
GGGCATTACGCTGGTGACGGCCAACACGGGAGAATTCAACCGGATCAAGGGCTTGAAGATCGAGAACTGGCTAGCATAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10206.70 Da        Isoelectric Point: 4.8952

>AT116058 WP_126043012.1 NZ_CP034443:c5616602-5616330 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
MPQRRHSTPPPKEAKLFRNNRSQAVRIPVEFELPGEKVLISREGDRLVIEPVRKPGLTALLAQWAKEPPLGPEDDFPEID
DAPIESVEIF

Download         Length: 273 bp

>AT116058 NZ_CP034443:c5616602-5616330 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
ATGCCCCAGCGCCGCCATTCAACCCCGCCACCGAAGGAGGCGAAGCTGTTCCGCAACAACCGCAGCCAGGCGGTGCGCAT
TCCCGTCGAGTTCGAGCTTCCCGGCGAAAAGGTCTTGATCAGCCGTGAAGGCGACCGCCTGGTCATCGAGCCGGTCCGCA
AACCTGGCCTCACAGCGCTGCTCGCCCAATGGGCGAAAGAGCCGCCGCTCGGTCCTGAAGACGACTTCCCGGAGATCGAC
GATGCGCCTATCGAATCCGTGGAAATTTTTTGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References