Detailed information of TA system TA116057

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-Xre
• Location: 3421459..3422329
• Replicon: chromosome
• Accession: NZ_CP034443
• Organism: Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: EJ066_RS16460
• Protein ID: WP_126039702.1
• Coordinates: 3421823..3422329 (+)
• Length: 169 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: EJ066_RS16455
• Protein ID: WP_126039700.1
• Coordinates: 3421459..3421830 (+)
• Length: 124 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EJ066_RS16435	3418440..3418728	+	289	Protein_3198	hypothetical protein	-
EJ066_RS16440	3418775..3419176	-	402	WP_126043913.1	GFA family protein	-
EJ066_RS16445	3419352..3420110	+	759	Protein_3200	TlyA family RNA methyltransferase	-
EJ066_RS16450	3420142..3421383	+	1242	WP_126039698.1	class I SAM-dependent RNA methyltransferase	-
EJ066_RS16455	3421459..3421830	+	372	WP_126039700.1	MbcA/ParS/Xre antitoxin family protein	Antitoxin
EJ066_RS16460	3421823..3422329	+	507	WP_126039702.1	RES domain-containing protein	Toxin
EJ066_RS16470	3422681..3424093	-	1413	WP_126039704.1	metalloprotease TldD	-
EJ066_RS16475	3424236..3424862	-	627	WP_126039707.1	invasion associated locus B family protein	-
EJ066_RS16480	3425204..3426118	+	915	WP_189644282.1	cytochrome c oxidase subunit II	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (7-161)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (71-120)

Sequences

Toxin

Protein

• Length: 169 a.a.
• Molecular weight: 18829.36 Da
• Isoelectric Point: 5.2262

>T116057 WP_126039702.1 NZ_CP034443:3421823-3422329 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
MPEASLTLWRAFVPRWAYLPLSGEGAARFGGRWNPLGAPTIYAARELSTAWAEYNQGFVQHPALIAQLELSGARLADLTD
TDTLTRLDVTADIHRCEWRDMLDRGLVPETHRLRDRLLAEGLHGVIYPSFMSPGGTCAALWRWNEDDAPGLEIIDPDHRL
PKTPASWL

Nucleotide

• Length: 507 bp

>T116057 NZ_CP034443:3421823-3422329 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
ATGCCTGAAGCCAGCCTAACCCTGTGGCGAGCCTTCGTGCCGCGCTGGGCGTATCTGCCGCTTTCGGGCGAGGGTGCTGC
CCGCTTCGGCGGACGCTGGAATCCGCTGGGCGCCCCGACGATCTACGCGGCACGGGAACTGTCCACCGCCTGGGCCGAAT
ACAATCAGGGCTTTGTCCAGCACCCGGCACTGATCGCCCAGCTTGAACTCTCAGGCGCGCGGCTGGCCGACCTGACAGAC
ACCGATACGCTGACCAGGCTCGATGTGACGGCTGACATTCATCGGTGTGAGTGGCGCGACATGCTGGATCGAGGCCTTGT
GCCAGAGACGCACAGGCTAAGAGATCGCTTGCTGGCCGAAGGGCTGCATGGCGTGATCTACCCATCCTTCATGTCGCCCG
GCGGCACATGCGCTGCACTCTGGCGCTGGAACGAGGACGACGCCCCGGGTCTCGAAATCATCGATCCGGACCATCGCCTG
CCGAAAACGCCGGCATCGTGGCTGTAG

Antitoxin

Protein

• Length: 124 a.a.
• Molecular weight: 13167.25 Da
• Isoelectric Point: 10.2186

>AT116057 WP_126039700.1 NZ_CP034443:3421459-3421830 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
MNSVALEIPASRFGEERSPFLSARRVAEQLGVTLTELASLIGVARNTLAAKTGARKVDAALSPIVRILAMAGEMAGGEQR
AAIWFKHQPIPGWAGKTAYDLVREGKTDKVLAYLEAVRSGIYA

Nucleotide

• Length: 372 bp

>AT116057 NZ_CP034443:3421459-3421830 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
ATGAATTCCGTGGCCCTCGAAATCCCTGCGTCGCGCTTCGGCGAGGAACGGTCGCCGTTCCTGTCAGCGAGGCGGGTCGC
CGAGCAGCTCGGCGTCACTCTAACTGAACTGGCGAGCCTGATCGGTGTCGCGCGCAACACGCTTGCGGCAAAGACAGGCG
CACGCAAGGTCGACGCCGCCCTCAGTCCGATCGTCCGCATCCTGGCGATGGCGGGCGAAATGGCCGGCGGCGAGCAGCGC
GCGGCGATCTGGTTCAAGCACCAGCCGATCCCCGGCTGGGCCGGAAAGACCGCCTACGATCTGGTTCGCGAGGGCAAGAC
GGACAAGGTGCTTGCCTATTTGGAGGCTGTCCGCTCCGGCATCTATGCCTGA