Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 1785879..1786564 Replicon chromosome
Accession NZ_CP034443
Organism Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EJ066_RS08960 Protein ID WP_126036865.1
Coordinates 1785879..1786301 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EJ066_RS08965 Protein ID WP_126043799.1
Coordinates 1786298..1786564 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJ066_RS08935 1781209..1782318 + 1110 WP_126036857.1 Gfo/Idh/MocA family oxidoreductase -
EJ066_RS08940 1782343..1783044 - 702 WP_126036859.1 YafY family transcriptional regulator -
EJ066_RS08945 1783172..1783807 + 636 WP_126043798.1 LysE family translocator -
EJ066_RS08950 1783906..1784997 - 1092 WP_126036861.1 3-deoxy-7-phosphoheptulonate synthase -
EJ066_RS08955 1785459..1785821 - 363 WP_126036863.1 hypothetical protein -
EJ066_RS08960 1785879..1786301 - 423 WP_126036865.1 type II toxin-antitoxin system VapC family toxin Toxin
EJ066_RS08965 1786298..1786564 - 267 WP_126043799.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
EJ066_RS08975 1786757..1787551 - 795 WP_126036867.1 SDR family oxidoreductase -
EJ066_RS08980 1787578..1788573 - 996 WP_126036869.1 inositol 2-dehydrogenase -
EJ066_RS08985 1788704..1789471 - 768 WP_126036871.1 sugar ABC transporter ATP-binding protein -
EJ066_RS08990 1789474..1790550 - 1077 WP_126036873.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(11-61)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15665.96 Da        Isoelectric Point: 4.5606

>T116056 WP_126036865.1 NZ_CP034443:c1786301-1785879 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
VRLLLDTNVLSEVTRPAPDARVLDWLDGLDEDRSFISVVSIAEIRRGVALMDEGRKREALAEWLAQDLPQRFEQRVLPVD
EPVALAWGDLMGLAKRRGRGLSSMDGLIAATAIARQLTLATRNMKDFEGFGFELFDPWTA

Download         Length: 423 bp

>T116056 NZ_CP034443:c1786301-1785879 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
GTGAGGCTACTGCTCGATACGAATGTCCTGTCCGAGGTGACAAGGCCGGCGCCGGACGCACGCGTTCTGGACTGGCTGGA
CGGGCTTGATGAGGACCGCTCATTCATCAGCGTCGTGTCAATCGCCGAGATCCGGCGTGGCGTCGCCCTCATGGATGAGG
GCCGGAAACGCGAGGCACTGGCCGAATGGCTAGCTCAGGATCTGCCGCAGCGCTTCGAGCAGAGGGTTCTTCCGGTGGAC
GAACCGGTTGCCTTGGCTTGGGGCGACCTGATGGGCCTTGCGAAGCGCCGGGGTCGCGGTCTGTCGTCAATGGACGGCCT
GATCGCAGCCACCGCGATTGCGCGGCAGCTCACCTTGGCAACGCGCAATATGAAGGATTTCGAAGGCTTTGGATTTGAAC
TCTTCGATCCCTGGACTGCGTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9787.07 Da        Isoelectric Point: 10.1756

>AT116056 WP_126043799.1 NZ_CP034443:c1786564-1786298 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
MQSAPKEGTNWTVAGAKARLSEVIERAQSSPQTITRNGKPSVVVVSAEEWQRKTARKGTLAEFLMESPLRGADLNLERQR
DEPRDLPL

Download         Length: 267 bp

>AT116056 NZ_CP034443:c1786564-1786298 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
ATGCAGTCTGCGCCTAAAGAGGGTACCAACTGGACGGTCGCCGGGGCAAAAGCCCGGCTCTCGGAGGTTATCGAGCGCGC
GCAGTCTTCGCCGCAGACGATCACCAGAAACGGCAAACCAAGCGTGGTTGTCGTCTCGGCCGAGGAATGGCAGCGCAAGA
CCGCGCGCAAGGGTACGCTTGCGGAGTTCCTGATGGAGTCGCCGCTGCGCGGCGCCGATCTCAACCTTGAGCGTCAGCGC
GACGAACCGCGTGATCTGCCGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References