Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 755175..755848 Replicon chromosome
Accession NZ_CP034443
Organism Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag EJ066_RS03745 Protein ID WP_126035021.1
Coordinates 755426..755848 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag EJ066_RS03740 Protein ID WP_126035019.1
Coordinates 755175..755429 (+) Length 85 a.a.

Genomic Context

EJ066_RS03700EJ066_RS03720EJ066_RS03725EJ066_RS03740EJ066_RS03745EJ066_RS03750EJ066_RS03770EJ066_RS03705EJ066_RS03710EJ066_RS03715EJ066_RS03730EJ066_RS03755EJ066_RS03760EJ066_RS03765
Location: 750447..751172 (726 bp)
Type: Others
Protein ID: WP_126035010.1
Location: 752978..753889 (912 bp)
Type: Others
Protein ID: WP_126035015.1
Location: 753998..754792 (795 bp)
Type: Others
Protein ID: WP_126035017.1
Location: 755175..755429 (255 bp)
Type: Antitoxin
Protein ID: WP_126035019.1
Location: 755426..755848 (423 bp)
Type: Toxin
Protein ID: WP_126035021.1
Location: 755929..756117 (189 bp)
Type: Others
Protein ID: WP_126035023.1
Location: 759331..760311 (981 bp)
Type: Others
Protein ID: WP_189644426.1
Location: 751192..751800 (609 bp)
Type: Others
Protein ID: WP_126035011.1
Location: 751813..752283 (471 bp)
Type: Others
Protein ID: WP_065009936.1
Location: 752319..752870 (552 bp)
Type: Others
Protein ID: WP_126035013.1
Location: 754819..754956 (138 bp)
Type: Others
Protein ID: Protein_721
Location: 756327..756944 (618 bp)
Type: Others
Protein ID: WP_126035025.1
Location: 757088..758035 (948 bp)
Type: Others
Protein ID: WP_126035027.1
Location: 758188..759156 (969 bp)
Type: Others
Protein ID: WP_189644425.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
EJ066_RS03700750447..751172+726WP_126035010.1YdcF family protein-
EJ066_RS03705751192..751800-609WP_126035011.1pyridoxamine 5'-phosphate oxidase family protein-
EJ066_RS03710751813..752283-471WP_065009936.1DUF1348 family protein-
EJ066_RS03715752319..752870-552WP_126035013.1carboxymuconolactone decarboxylase family protein-
EJ066_RS03720752978..753889+912WP_126035015.1LysR family transcriptional regulator-
EJ066_RS03725753998..754792+795WP_126035017.11-acyl-sn-glycerol-3-phosphate acyltransferase-
EJ066_RS03730754819..754956-138Protein_721LysE family translocator-
EJ066_RS03740755175..755429+255WP_126035019.1plasmid stabilization proteinAntitoxin
EJ066_RS03745755426..755848+423WP_126035021.1type II toxin-antitoxin system VapC family toxinToxin
EJ066_RS03750755929..756117+189WP_126035023.1hypothetical protein-
EJ066_RS03755756327..756944-618WP_126035025.1LysE family translocator-
EJ066_RS03760757088..758035-948WP_126035027.1aldo/keto reductase-
EJ066_RS03765758188..759156-969WP_189644425.1helix-turn-helix domain-containing protein-
EJ066_RS03770759331..760311+981WP_189644426.1zinc-binding dehydrogenase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-122)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 14706.81 Da        Isoelectric Point: 5.5423

>T116054 WP_126035021.1 NZ_CP034443:755426-755848 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
MIVLDTNVVSEAMKPEPAPIVRGWLDEQAAETLYLSSVTIAELLFGTGALPDGRRKQKLATTLDGLLGLFDGRILPFDTD
AARHYADLAVAAHNAGKGFPTPNGYIAAIATAHGFAVATRDASAFIAAGVPVIDPWKPGH

Download         Length: 423 bp

>T116054 NZ_CP034443:755426-755848 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
ATGATCGTTCTGGACACGAATGTCGTCTCCGAGGCGATGAAGCCAGAGCCGGCCCCCATCGTTCGCGGCTGGCTGGACGA
GCAGGCTGCTGAAACCCTCTATCTCTCCAGCGTGACCATCGCCGAACTGCTGTTCGGCACCGGTGCGCTACCTGATGGGC
GACGCAAGCAGAAGCTCGCGACGACGCTAGACGGGCTTCTCGGCCTCTTCGACGGCAGAATCCTCCCTTTCGATACAGAT
GCCGCCCGTCATTATGCCGACCTGGCCGTCGCAGCCCACAACGCGGGCAAGGGTTTTCCCACGCCCAACGGATATATCGC
GGCCATCGCGACGGCCCACGGCTTCGCGGTTGCGACCCGCGACGCCAGTGCCTTCATTGCGGCAGGCGTCCCGGTGATTG
ACCCTTGGAAGCCCGGACACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9110.23 Da        Isoelectric Point: 6.2207

>AT116054 WP_126035019.1 NZ_CP034443:755175-755429 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
MPAVTIRNLSEEAHRALKVRAAHHGRSTEAEIRDILEAAVRPANRIRIGSALSALSRDAGLTNADFEALEEGCDRTPATP
MSFE

Download         Length: 255 bp

>AT116054 NZ_CP034443:755175-755429 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
ATGCCCGCCGTCACCATTCGTAACCTGTCCGAGGAAGCACACCGCGCCCTCAAGGTGCGCGCGGCCCATCATGGTCGTAG
CACCGAGGCCGAAATACGCGACATTCTGGAAGCGGCGGTTCGCCCCGCCAACCGCATTCGTATCGGCTCCGCCTTGTCGG
CGTTGAGCCGCGACGCCGGGCTGACCAATGCCGATTTCGAGGCGCTGGAAGAGGGCTGCGACAGGACGCCCGCCACGCCG
ATGAGCTTCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References