Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VagC |
| Location | 221510..222138 | Replicon | chromosome |
| Accession | NZ_CP034443 | ||
| Organism | Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | EJ066_RS01145 | Protein ID | WP_126034431.1 |
| Coordinates | 221510..221896 (-) | Length | 129 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | EJ066_RS01150 | Protein ID | WP_126034432.1 |
| Coordinates | 221893..222138 (-) | Length | 82 a.a. |
Genomic Context
Location: 217021..218112 (1092 bp)
Type: Others
Protein ID: WP_126034428.1
Type: Others
Protein ID: WP_126034428.1
Location: 218361..220550 (2190 bp)
Type: Others
Protein ID: WP_126034429.1
Type: Others
Protein ID: WP_126034429.1
Location: 220556..221503 (948 bp)
Type: Others
Protein ID: WP_126034430.1
Type: Others
Protein ID: WP_126034430.1
Location: 223386..223823 (438 bp)
Type: Others
Protein ID: WP_126034434.1
Type: Others
Protein ID: WP_126034434.1
Location: 223892..224692 (801 bp)
Type: Others
Protein ID: WP_126034435.1
Type: Others
Protein ID: WP_126034435.1
Location: 224739..225047 (309 bp)
Type: Others
Protein ID: WP_126034436.1
Type: Others
Protein ID: WP_126034436.1
Location: 225120..226208 (1089 bp)
Type: Others
Protein ID: WP_126034437.1
Type: Others
Protein ID: WP_126034437.1
Location: 221510..221896 (387 bp)
Type: Toxin
Protein ID: WP_126034431.1
Type: Toxin
Protein ID: WP_126034431.1
Location: 221893..222138 (246 bp)
Type: Antitoxin
Protein ID: WP_126034432.1
Type: Antitoxin
Protein ID: WP_126034432.1
Location: 222215..223288 (1074 bp)
Type: Others
Protein ID: WP_126034433.1
Type: Others
Protein ID: WP_126034433.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EJ066_RS01130 | 217021..218112 | + | 1092 | WP_126034428.1 | succinylglutamate desuccinylase/aspartoacylase family protein | - |
| EJ066_RS01135 | 218361..220550 | + | 2190 | WP_126034429.1 | anthranilate synthase | - |
| EJ066_RS01140 | 220556..221503 | + | 948 | WP_126034430.1 | cation diffusion facilitator family transporter | - |
| EJ066_RS01145 | 221510..221896 | - | 387 | WP_126034431.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| EJ066_RS01150 | 221893..222138 | - | 246 | WP_126034432.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
| EJ066_RS01155 | 222215..223288 | - | 1074 | WP_126034433.1 | hypothetical protein | - |
| EJ066_RS01160 | 223386..223823 | + | 438 | WP_126034434.1 | DsrE family protein | - |
| EJ066_RS01165 | 223892..224692 | + | 801 | WP_126034435.1 | SDR family oxidoreductase | - |
| EJ066_RS01170 | 224739..225047 | + | 309 | WP_126034436.1 | antibiotic biosynthesis monooxygenase | - |
| EJ066_RS01175 | 225120..226208 | + | 1089 | WP_126034437.1 | AbrB family transcriptional regulator | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 129 a.a. Molecular weight: 14381.43 Da Isoelectric Point: 8.4337
>T116053 WP_126034431.1 NZ_CP034443:c221896-221510 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
VIYLLDTNAVIAIMKGDADLQARLKPYRPQDFALSAIVVHELYYGAQKSQRKADNLARIEALQFPVLEFDREDARHAGEI
RATLATSGTPIGPYDALIGGQARARNLTLITRNAREFERIKNLTIETW
VIYLLDTNAVIAIMKGDADLQARLKPYRPQDFALSAIVVHELYYGAQKSQRKADNLARIEALQFPVLEFDREDARHAGEI
RATLATSGTPIGPYDALIGGQARARNLTLITRNAREFERIKNLTIETW
Download Length: 387 bp
>T116053 NZ_CP034443:c221896-221510 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
GTGATCTATCTGCTCGACACCAATGCGGTCATCGCGATCATGAAAGGTGACGCAGATCTGCAGGCACGGCTCAAGCCATA
CAGGCCGCAGGATTTCGCACTTTCGGCCATTGTCGTGCACGAACTCTACTACGGTGCTCAAAAGAGCCAGCGAAAGGCCG
ACAATCTGGCGCGCATCGAAGCGCTCCAGTTCCCGGTACTCGAATTCGATCGGGAAGATGCAAGGCATGCCGGCGAGATT
CGGGCGACGCTTGCGACGTCAGGGACCCCGATTGGTCCCTATGATGCGCTGATTGGTGGGCAGGCGCGGGCCCGGAACCT
CACGCTGATAACCCGCAATGCACGGGAATTCGAGCGGATCAAAAACCTCACAATCGAGACCTGGTGA
GTGATCTATCTGCTCGACACCAATGCGGTCATCGCGATCATGAAAGGTGACGCAGATCTGCAGGCACGGCTCAAGCCATA
CAGGCCGCAGGATTTCGCACTTTCGGCCATTGTCGTGCACGAACTCTACTACGGTGCTCAAAAGAGCCAGCGAAAGGCCG
ACAATCTGGCGCGCATCGAAGCGCTCCAGTTCCCGGTACTCGAATTCGATCGGGAAGATGCAAGGCATGCCGGCGAGATT
CGGGCGACGCTTGCGACGTCAGGGACCCCGATTGGTCCCTATGATGCGCTGATTGGTGGGCAGGCGCGGGCCCGGAACCT
CACGCTGATAACCCGCAATGCACGGGAATTCGAGCGGATCAAAAACCTCACAATCGAGACCTGGTGA
Antitoxin
Download Length: 82 a.a. Molecular weight: 9382.58 Da Isoelectric Point: 4.5257
>AT116053 WP_126034432.1 NZ_CP034443:c222138-221893 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
MEKAKVFWSGRSQAVRLPKEFRFETDEVSIRRHGQSIILEPLAKDWAWLDQVIGPLDDDFAEAALERPAEQDRPALDDVF
K
MEKAKVFWSGRSQAVRLPKEFRFETDEVSIRRHGQSIILEPLAKDWAWLDQVIGPLDDDFAEAALERPAEQDRPALDDVF
K
Download Length: 246 bp
>AT116053 NZ_CP034443:c222138-221893 [Mesorhizobium sp. M9A.F.Ca.ET.002.03.1.2]
ATGGAAAAAGCAAAGGTGTTCTGGTCAGGCCGCTCGCAGGCGGTGCGGCTGCCAAAGGAATTCCGTTTCGAAACCGATGA
GGTTTCGATTCGCCGCCATGGCCAGAGTATAATCCTCGAACCGCTCGCGAAGGACTGGGCCTGGCTCGACCAGGTGATAG
GTCCGCTTGACGATGATTTCGCCGAGGCAGCACTGGAACGTCCAGCTGAGCAGGACCGGCCGGCTTTGGATGACGTTTTC
AAGTGA
ATGGAAAAAGCAAAGGTGTTCTGGTCAGGCCGCTCGCAGGCGGTGCGGCTGCCAAAGGAATTCCGTTTCGAAACCGATGA
GGTTTCGATTCGCCGCCATGGCCAGAGTATAATCCTCGAACCGCTCGCGAAGGACTGGGCCTGGCTCGACCAGGTGATAG
GTCCGCTTGACGATGATTTCGCCGAGGCAGCACTGGAACGTCCAGCTGAGCAGGACCGGCCGGCTTTGGATGACGTTTTC
AAGTGA