Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF(toxin)
Location 6346765..6347391 Replicon chromosome
Accession NZ_CP034437
Organism Paenibacillus albus strain 18JY67-1

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag EJC50_RS28695 Protein ID WP_090581240.1
Coordinates 6346765..6347115 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag EJC50_RS28700 Protein ID WP_178075161.1
Coordinates 6347119..6347391 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EJC50_RS28680 6343171..6345051 - 1881 WP_126019574.1 sensor histidine kinase -
EJC50_RS28685 6345223..6345897 - 675 WP_126019576.1 hypothetical protein -
EJC50_RS28690 6345908..6346600 - 693 WP_126019578.1 hypothetical protein -
EJC50_RS28695 6346765..6347115 - 351 WP_090581240.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
EJC50_RS28700 6347119..6347391 - 273 WP_178075161.1 ribbon-helix-helix protein, CopG family Antitoxin
EJC50_RS28705 6347639..6348823 - 1185 WP_126019581.1 alanine racemase -
EJC50_RS28710 6348989..6350302 - 1314 WP_126019583.1 DUF4367 domain-containing protein -
EJC50_RS28715 6350477..6351451 - 975 WP_126019585.1 undecaprenyl/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-110)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12832.80 Da        Isoelectric Point: 5.1284

>T116030 WP_090581240.1 NZ_CP034437:c6347115-6346765 [Paenibacillus albus]
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAALHGFDRDSVLLLEQI
RTIDKQRLTDKITHLDDETMRKVDEALQISVGLIDF

Download         Length: 351 bp

>T116030 NZ_CP034437:c6347115-6346765 [Paenibacillus albus]
TTGATCGTTAAACGCGGCGATGTGTTTTTTGCTGATTTGTCACCTGTTGTCGGTTCTGAACAGGGAGGAGTGCGTCCTGT
TCTCGTTATTCAAAATGATATTGGCAACCGCTTTAGTCCAACCGTCATTGTAGCTGCGATTACAGCTCAAATACAGAAGG
CTAAGCTGCCGACGCATGTAGAGATTGATGCGGCGCTTCATGGGTTTGACCGTGATTCCGTCCTTCTTCTCGAACAGATT
CGCACGATTGATAAACAGCGTCTTACCGACAAGATCACACACCTCGACGATGAAACGATGCGCAAAGTAGACGAGGCGCT
GCAGATCAGCGTTGGCCTTATTGATTTTTGA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10354.95 Da        Isoelectric Point: 7.0150

>AT116030 WP_178075161.1 NZ_CP034437:c6347391-6347119 [Paenibacillus albus]
MQNTKRIMISLPDHLLEEVDGIVARENSNRSEFIRQAMKLYLIERKKRQIRDSMQRGYLEMAKINLVMASEAFQAEEDAG
DTLGRLVSGV

Download         Length: 273 bp

>AT116030 NZ_CP034437:c6347391-6347119 [Paenibacillus albus]
ATGCAAAACACCAAAAGGATTATGATCAGCTTACCGGATCATTTGCTGGAGGAAGTCGACGGAATCGTCGCCAGAGAAAA
CTCGAACCGGAGCGAATTTATTCGTCAGGCAATGAAATTGTACTTGATTGAACGGAAGAAACGTCAGATTCGCGATTCGA
TGCAGCGCGGCTATTTGGAAATGGCCAAAATCAACTTAGTGATGGCGTCGGAAGCTTTTCAAGCGGAGGAAGATGCCGGC
GATACGCTCGGCCGACTCGTAAGCGGGGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References